Clinical trials: Disturbed Sleep
Attention-Deficit/Hyperactivity Disorder, Attention Deficit Disorder
Effect of Guanfacine Extended-Release on Attention Deficit Hyperactivity Disorder (ADHD)-Associated Insomnia
This study seeks to determine, using special sleep tests (polysomnography and actigraphy) if guanfacine extended release is able to improve nighttime sleep in children with ADHD - associated insomnia while improving daytime ADHD…
- Conditions
- Attention-Deficit/Hyperactivity Disorder, Attention Deficit Disorder, Insomnia, Sleep Disorders
- Trial name
- NCT01156051
- Testing
- Guanfacine extended-release tablets
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Children's Specialized Hospital
Cancer Pain
An Efficacy and Safety Study of Hydromorphone Oral Osmotic System (OROS) in Korean Participants With Cancer Pain
The purpose of this is study to evaluate improvement of sleep disorder caused by cancer pain after the administration of Hydromorphone Oral Osmotic System (OROS) in Korean participants with cancer.
- Trial name
- NCT00766831
- Testing
- Hydromorphone
- Volunteers
- 190 people
- Sponsor
- Janssen Korea, Ltd., Korea
Rheumatic Diseases
A Study on Health - Related Quality of Life in Patients With Rheumatic Diseases Taking Tramadol 37.5mg/Acetaminophen 325mg Tablets
The objective of this observational study is to assess improvement of quality of life in the patients who are administered Tramadol 37.5mg/Acetaminophen 325mg tablets for 10~14 weeks according to the investigator's discretion in…
- Trial name
- NCT00642837
- Testing
- Tramadol/acetaminophen
- Volunteers
- 982 people
- Sponsor
- Janssen Korea, Ltd., Korea
Skin Condition, Sleep Disturbance
Efficacy Testing of Collagen Drink on Skin Beauty and Sleep Aid
To assess Collagen Drink on skin condition and sleep quality improvement
- Trial name
- NCT05182814
- Testing
- Collagen Juice Drink
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Moderate-to-severe Psoriasis
The Relationship Between Moderate-to-severe Psoriasis and Sleep Disturbance
Psoriasis is a common chronic and systemic immune-mediated disease, induced by a combination of genetic and environmental effects.
- Trial name
- NCT06165887
- Testing
- No intervention
- Where
- China
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Nocturia, Hypertension
Sleep, Hypertension, and Nocturia: a Multicomponent Approach for Comorbid Illnesses
In this study the investigators target three common and comorbid illnesses among older adults namely nocturia or waking at night to void, poor sleep and hypertension.
- Conditions
- Nocturia, Hypertension, Sleep Disturbance
- Trial name
- SHyN (NCT05419830)
- Testing
- BBTI, PM antihypertensive dosing or Chronotherapy, AM antihypertensive dosing
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Cocaine Use Disorder, Sleep Disturbance
Subjective Sleep Quality in CUD TMS-Treated
Sleep disruptions are prevalent complaints in cocaine use disorder (CUD) subjects, either during consumption or withdrawal. Repetitive transcranial magnetic stimulation (rTMS) seem to be a promissing strategy in the treatment of…
- Trial name
- NCT03733821
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Fondazione Novella Fronda
Alzheimer's Disease
Effects of Light-therapy in Alzheimer's Disease
Background: Management of patients with Alzheimer's disease associated with behavioral disturbances is difficult especially in those with agitation/aggression and insomnia and nighttime behaviors.
- Trial name
- ALZ-Light (NCT02686190)
- Testing
- Luxtherapy
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fatigue, Depression
Adaptive Symptom Care Using Fish-Based Nutritional Directives Post Breast Cancer
Inflammation has been consistently associated with psychoneurological symptoms (PNS) among breast cancer survivors (BCS). Evidence supporting interventional strategies promoting symptom-self management in reducing…
- Conditions
- Fatigue, Depression, Pain, Sleep Disturbance
- Trial name
- NCT04293874
- Testing
- Personalized Meal Plan, Dietary Omega-3LC intervention
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Connecticut
Postoperative Pain, Acute, Postoperative Depression
REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss
The purpose of this research study is to learn how two different supportive programs may help women feel better after surgery. This study will measure if one type of supportive program is more useful than the other for improving…
- Conditions
- Postoperative Pain, Acute, Postoperative Depression, Anxiety, Sleep Disturbance
- Trial name
- NCT05625360
- Testing
- eHealth Mindful Movement and Breathing, Life Impacts Reflection, PROMIS Questionnaires
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Sleep Disorder, Healthy
Effects of Experimental Sleep Disturbances on Receptor Function of Study Drug
The overall goal of this project is to determine whether common sleep disturbance patterns, sleep continuity disturbance (SCD) and Sleep Fragmentation (SF), alter cerebral study drug receptor availability, drug-based analgesia…
- Trial name
- Sleep-MOR (NCT04299490)
- Testing
- Sleep Fragmentation, Sleep Continuity Disruption, Undisturbed Sleep
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Short-term Insomnia
Pilot Study of a Combination Drug Product for Treatment of Short-term Insomnia
The purpose of this study is to evaluate the effect of a combination drug product containing diphenhydramine, zolpidem and lorazepam on total sleep time.
- Trial name
- NCT02671760
- Testing
- SM-1, Comparator
- Volunteers
- 39 people
- Sponsor
- Sequential Medicine Ltd
Depressive Symptoms, Sleep Disturbance
Effects of Exercise Intervention on Sleep Quality and Emotional Problems in College Students With Depressive Symptoms
This exploratory randomized controlled trial aims to investigate the immediate and long-term effects of exercise on sleep quality, emotional problems, executive function, and neurophysiological characteristics in college students…
- Trial name
- NCT07738809
- Testing
- Archery Exercise, Non-exercise Control
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Capital University of Physical Education and Sports, China
Transcutaneous Electric Nerve Stimulation, Rheumatoid Arthritis
Effect of Transcutaneous Auricular Electroacupuncture on Sleep Disturbances in Patients With Rheumatoid Arthritis: A Randomized Double-Blind Clinical Trial
The purpose of this clinical trial is to determine whether transcutaneous auricular vagus nerve stimulation (taVNS) is suitable for improving sleep disorders in patients with rheumatoid arthritis (RA).
- Conditions
- Transcutaneous Electric Nerve Stimulation, Rheumatoid Arthritis, Sleep Quality
- Trial name
- NCT06527547
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Juan Jiao
Sleep Disturbance, Nursing Care
The Effect of Progressive Relaxation Exercises on Sleep Quality
This study; In order to investigate the effect of progressive relaxation exercises on sleep quality, serotonin and melatonin levels in cardiac patients with sleep problems, a pretest/posttest experimental design study will be…
- Trial name
- NCT05647148
- Testing
- Progressive Relaxation Exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Sleep, Pain
Acupuncture for Pain and Sleep Disturbance in Knee Osteoarthritis
The hypotheses of this study are: In the older population with knee OA, When acupoints are chosen for both sleep and pain, there are additive effects on sleep improvement and pain relief (i.e. no interaction).
- Trial name
- NCT00694447
- Testing
- Acupuncture
- Where
- United States
- Sponsor
- Emory University
Sleep Initiation and Maintenance Disorders, Stress Disorders, Posttraumatic
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
Post-traumatic stress disorder (PTSD) is a common consequence of combat that can result in trauma-related hyperarousal and sleep disturbances.
- Trial name
- NCT03642028
- Testing
- Suvorexant
- Where
- 4 sites in United States
- Volunteers
- 190 people
- Sponsor
- VA Office of Research and Development
Sleep Disturbance, Amnestic Mild Cognitive Impairment
Sleep Interventions and Neurocognitive Outcomes
This protocol focuses on the effect of sleep interventions on improving sleep and building cognitive/brain resilience in older adults with amnestic mild cognitive impairment and sleep disturbance.
- Trial name
- SINA (NCT05987007)
- Testing
- Acoustic slow-wave activity enhancement, Cognitive behavioral therapy for insomnia
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- New York State Psychiatric Institute
Parkinson Disease
Parkinson's Disease Progression Study
Disease Progression Study
- Trial name
- NCT06219629
- Where
- 10 sites in United States
- Volunteers
- 82 people
- Sponsor
- Koneksa Health
Alzheimer Disease, Dementia
Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase
This study seeks to improve clinical outcomes for an important, growing, and vulnerable population-nursing home residents with Alzheimer's disease or related dementias-by testing an evidence-based intervention to improve these…
- Conditions
- Alzheimer Disease, Dementia, Sleep Disorder, Sleep Disturbance
- Trial name
- 40Winks (NCT05820919)
- Testing
- LOCK Sleep Program, No intervention (control period/baseline data collection)
- Where
- 3 sites in United States
- Volunteers
- 456 people
- Sponsor
- University of Alabama, Tuscaloosa