Clinical trials: Diving Medicine
Healthy Volunteers
Effects of Levocetirizine and Hydroxyzine on Cognitive and Psychomotor Functioning During Simulated Diving
Antihistamines are commonly used and currently levocetirizine is most frequently prescribed in the Netherlands. They are commonly used by divers, to solve ear, nose and throat problems, especially to open tubal passage.
- Trial name
- NCT01496911
- Testing
- Levocetirizine, Hydroxyzine
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
Saturation Exposure, Decompression Injury
Inflammatory and Cerebrospinal Biochemical Markers in Blood During Prolonged Hyperbaric Exposure
Research hypothesis Prolonged hyperbaric exposure will affect the central nervous system Prolonged hyperbaric exposure will induce inflammatory changes Prolonged hyperbaric exposure will affect fluid regulation in the body…
- Trial name
- Mättnad2017 (NCT03192930)
- Testing
- Hyperbaric exposure
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Sahlgrenska University Hospital
Oxygen Toxicity, Oxidative Stress
Effect of Hydrogen Gas on Hyperbaric Oxygen Toxicity
The goal of this trial is to investigate whether adding a small fraction of hydrogen gas to an oxygen-enriched breathing mixture can reduce pulmonary oxygen toxicity (POT) in healthy and active divers from the Swedish Armed…
- Conditions
- Oxygen Toxicity, Oxidative Stress, Hyperoxia, Hyperbaric Oxygen
- Trial name
- NCT07263399
- Testing
- Inhaled Hydrogen-Enriched Oxygen Gas, Inhaled Nitrogen-Enriched Oxygen Gas
- Where
- 2 sites in Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Diabetes Mellitus, Type 2
A Study Based on Data From German Registries That Looks at Characteristics of People Who Take the Medicine Empagliflozin for Type 2 Diabetes
Description of the real-life treatment of adult patients with type-2 diabetes mellitus (T2DM) receiving Empagliflozin, comparing the characteristics of patients starting Empagliflozin in three time intervals
- Trial name
- EDCOS (NCT04098575)
- Testing
- Empagliflozin
- Where
- Germany
- Volunteers
- 9,571 people
- Sponsor
- Boehringer Ingelheim
Hyperbaric, Diving Medicine
Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air
Primary objective: Assessment of venous gas emboli load post diving when breathing normobaric oxygen compared to air. Secondary objective: Assessment of fluid markers of central nervous system injury in blood post diving…
- Conditions
- Hyperbaric, Diving Medicine, Decompression Sickness, Central Nervous Injury
- Trial name
- NCT02468752
- Testing
- Oxygen, Air
- Where
- 2 sites in Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Diving Medicine, Inflammation
Inflammatory and Cerebrospinal Biochemical Markers in Blood After Trimix Diving
Research hypothesis Diving to depths up to 90msw with an oxygen partial pressure of 130kPa in the breathing gas will affect the central nervous system.
- Conditions
- Diving Medicine, Inflammation, Central Nervous System Injury
- Trial name
- TriMix17-18 (NCT03190252)
- Testing
- Exposure to oxygen partial pressure of 130 kPa, Exposure to ambient pressure of maximum 11 ATA
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital