Clinical trials: Donor
Cardiac Allograft Vasculopathy, Antibody Mediated Rejection
Endothelial Injury and Development of Coronary Intimal Thickening After Heart Transplantation
Coronary allograft vasculopathy (CAV) is the leading cause of late graft failure and second leading cause of late mortality after heart transplantation.
- Trial name
- NCT01848301
- Testing
- Optical Coherence Tomography, Acetylcholine, Brachial Artery Flow Mediated Dilation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Gladwin, Mark, MD
Free Gingival Graft
The Use of Flowable Resin Composite Stent in Reduction of Donor Site Morbidity After Free Gingival Graft Harvesting
After harvesting free gingival graft from the hard palate, Postoperative pain as well as bleeding are the most common complications.Different agents were used to protect the denuded areas on the palate as gelatin sponge…
- Trial name
- NCT05779800
- Testing
- Flowble resin composite stent, periodontal pack
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hematological Malignancies, Haploidentical Stem Cell Transplantation
Impact of Donor-recipient ABO Matching on Haploidentical Stem Cell Transplantation
the impact of donor-recipient ABO matching on outcome of peripheral blood stem cell haploidentical hematopoietic stem cell transplantation
- Trial name
- NCT05103995
- Testing
- no intervention
- Where
- 2 sites in China
- Volunteers
- 510 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Fertility
Human Sperm Markers of Cryodamage Resistance
Sperm freezing has been employed for decades for male fertility preservation in cases of foreseeable or unexpected loss of fertility to guarantee future paternity, and also as a complement of assisted reproduction techniques.
- Trial name
- NCT02535377
- Testing
- Sperm cryopreservation
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI Alicante
Tissue and Organ Procurement, Alcohol Abstinence
Intervention to Motivate Teens to be a Designated Organ Donor on Driver's License
This study will test the effectiveness of a multimedia campaign to educate ethnic minority teens about the choice to become a designated organ donor on their first driver's license.
- Trial name
- Idecide (NCT00810901)
- Testing
- Organ Donor, Alcohol Prevention
- Where
- United States
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Autism Spectrum Disorder, Autism
Safety and Efficacy of the Transfusion of UCB in Patients With an ASD Depending on the Degree of HLA Compatibility.
Autism is one of those disorders in Autism spectrum disorders (ASD), which characterized by social interaction abnormalities, impaired verbal and non-verbal communication, and repetitive, obsessive behavior, while the therapeutic…
- Trial name
- ASD-HLA2019 (NCT04099381)
- Testing
- ASD CB-MNC infusion low level HLA compatibility., ASD CB-MNC infusion high level HLA compatibility., Standard therapy.
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- State-Financed Health Facility "Samara Regional Medical Center Dinasty"
Laparoscopic Donor Nephrectomy, Perioperative Pain Management
Comparison of Spinal Anesthesia Adjuvant and Quadratus Lumborum Block on the Opioid Requirement and Perioperative Pain of Laparoscopic Kidney Transplant Donor
This study aims to compare the effectiveness of spinal anesthesia adjuvant and quadratus lumborum block on the opioid requirement and perioperative pain on patients undergoing laparoscopic kidney transplant donor.
- Trial name
- NCT06764667
- Testing
- Spinal anesthesia adjuvant, Quadratus Lumborum Block (QLB), General Anesthesia
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Living Donor Liver Transplantation
Effect of Ascites Replacement Strategy on Time to 1st Flatus After LDLT
The aim of this study is to evaluate difference in the rate of recovery of intestinal motility according to different ascites replacement strategy after living donor liver transplantation.
- Trial name
- NCT04184401
- Testing
- Ascites replacement with albumin and hartmann's solution, Ascites replacement with hartmann's solution
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Seoul National University Hospital
Delayed Graft Function
Renaparin® in Kidney Transplantation
This study evaluates the safety and tolerability of Renaparin in adult patients receiving a deceased donor kidney treated ex-vivo with Renaparin prior to transplantation.
- Trial name
- NCT03773211
- Testing
- Renaparin
- Where
- 3 sites in Sweden
- Volunteers
- 16 people
- Sponsor
- Corline Biomedical AB
Cellular Immunotherapy, Adoptive, Genetic Therapy
Long-Term Follow up of Patients Undergoing Hematopoietic Stem Cell Transplantation, Cellular Therapy, or Gene Therapy
Background: People who have had an allogeneic hematopoietic stem cell transplant (HCT), cellular therapy (CT), or gene therapy (GT) have bone marrow or an immune system that is damaged.
- Conditions
- Cellular Immunotherapy, Adoptive, Genetic Therapy, Tissue Donors, Hematopoietic Stem Cell Transplantation
- Trial name
- NCT03000244
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Living Donor Kidney Transplantation
Multidisciplinary Support to Access Living Donor Kidney Transplant (MuST AKT)
For people living with kidney failure, the two active treatment options are dialysis or kidney transplantation. Transplantation is optimal, and especially from a living donor - offering patients longer survival, a better quality…
- Trial name
- MuST AKT (NCT05459337)
- Testing
- MuST AKT
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University of Alberta
Leukemia, Lymphoblastic (Acute)
Administration of Donor MultiTAA-Specific T Cells for ALL
This study uses special blood cells called multiple tumor-associated antigen (TAA)-specific T cells to treat patients with acute lymphoblastic leukemia (ALL) which has come back, or may come back, or has not gone away after…
- Trial name
- STELLA (NCT02475707)
- Testing
- MultiTAA-specific T cells
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Hematopoietic Cell Transplantation Recipient, Refractory B-Cell Non-Hodgkin Lymphoma
Gemcitabine Hydrochloride, Clofarabine, and Busulfan Before Donor Stem Cell Transplant in Treating Patients With Refractory B-Cell or T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma
This phase I/II trial studies the side effects and best dose of gemcitabine hydrochloride, clofarabine, and busulfan before donor stem cell transplant and to see how well it works in treating patients with B-cell or T-cell…
- Conditions
- Hematopoietic Cell Transplantation Recipient, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Hodgkin Lymphoma, Refractory T-Cell Non-Hodgkin Lymphoma
- Trial name
- NCT01701986
- Testing
- Allogeneic Bone Marrow Transplantation, Allogeneic Hematopoietic Stem Cell Transplantation, Anti-Thymocyte Globulin
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Hematologic Malignancy
ATG Plus Low-dose PT-Cy for GVHD Prevention
During the past decades, the wider application of easily available haploidentical donor hematopoietic cell transplant (haplo-HCT) has been made possible through the T cell-replete (TCR) regimens including T cell regulation with…
- Trial name
- NCT06108739
- Testing
- Cyclophosphamid, ATG
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Peking University People's Hospital
Fertility
Evaluate Educational Interventions for Increasing Fertility Knowledge and Awareness
Fertility knowledge and awareness is considered insufficient in women of reproductive age from developed countries. The objective of this study is to evaluate if educational interventions in oocyte donors increase on their level…
- Trial name
- QUESE2 (NCT02364739)
- Testing
- Written information, Written and oral information
- Where
- Spain
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Fundació Privada Eugin
Leukemia, Lymphoma
CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant
CD34+ stem cell selection in children, adolescents and young adults receiving partially matched family donor or matched unrelated adult donor allogeneic bone marrow or peripheral blood stem cell transplant will be safe and well…
- Conditions
- Leukemia, Lymphoma, Bone Marrow Failure, Immunodeficiencies
- Trial name
- NCT01049854
- Testing
- Full Intensity with TBI, Full Intensity, Reduced Intensity
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- New York Medical College
Liver Transplant; Complications, Liver Transplant Rejection
Mortality, Morbidity and Risk Factors of Liver Retransplantation
This study aims to compare the short and long term outcomes of living donor and deceased donor liver retransplantation. Bearing that in mind, the investigators will retrospectively analyze the files of patients whom underwent a…
- Conditions
- Liver Transplant; Complications, Liver Transplant Rejection, Liver Transplant Failure, Liver Diseases
- Trial name
- NCT04789213
- Testing
- Liver Transplantation
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Memorial Bahçelievler Hospital
Bone Marrow Transplant
Pneumonia Vaccine in Bone Marrow Transplant Recipients: Usefulness of Donor Vaccination
Streptococcus pneumoniae, also known as Pneumococcus, is a common cause of pneumonia in transplant patients. There has been a vaccine available for this infection called Pneumovax.
- Trial name
- NCT00143780
- Testing
- The polysaccharide vaccine used is Pneumovax (Merck vaccines), The conjugate vaccine used is Prevnar (Wyeth-Ayerst vaccines)
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University Health Network, Toronto
Outcome During r-hFSH Stimulation, Outcome During r-hFSH and r-hLH Stimulation
Use of r-hLH (Luveris) in Donors Previously Treated With r-hFSH (Gonal F)
The purpose of the study is to compare the safety and efficacy of r-hLH to r-hFSH in the late follicular phase of young women undergoing controlled ovarian stimulation for oocyte donation.
- Trial name
- NCT01223079
- Testing
- r-hFSH, r-hFSH and r-hLH
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
HIV Infections
HIV Assessment in Fuyang, Anhui Province, China
The purpose of this study was to examine the needs, concerns, stigmas, and social networks of HIV infected former plasma donors (FPDs) and their relatives in Fuyang, Anhui Province, China.
- Trial name
- NCT00094354
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
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