Clinical trials: Dorsal Pathway
Failed Back Surgery Syndrome, Chronic Pain
Patient Profiling and Outcome Assessment in Spinal Cord Stimulation for Chronic Back and/or Leg Pain
The PROSTIM study is an ongoing prospective, multicentric and observational clinical study. Patients are recruited in three different centers in Eastern Belgium from May 2018 onwards.
- Trial name
- PROSTIM (NCT05349695)
- Testing
- Spinal cord stimulation
- Where
- 3 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Studie- & Opleidingscentrum Neurochirurgie Virga Jesse
Analgesia, Scoliosis Idiopathic
Multidisciplinary Perioperative Care Pathway in Adolescents Undergoing Posterior Spinal Fusion Surgery
Posterior Spinal fusion (PSF) is one of the most invasive orthopedic surgical procedures in children and adolescents, often characterized by extensive tissue trauma, and severe postoperative pain.
- Conditions
- Analgesia, Scoliosis Idiopathic, Surgery, Postoperative Pain
- Trial name
- NCT04038229
- Testing
- Enhanced recovery pathway
- Where
- Belgium
- Volunteers
- 33 people
- Sponsor
- University Hospital, Antwerp
Chronic Low-back Pain (cLBP), High-Impact Chronic Pain (HICP)
Comparing Non-Medicine Strategies for Improving Low Back Pain
The goal of this clinical trial is to help veterans manage high-impact chronic pain (HICP) in the lower back. The trial will use a program, ENCompaSS (Education, Navigated Care, and Supported Self-Management) designed to reduce…
- Trial name
- NCT07679178
- Testing
- ENCompaSS (Education, Navigated Care, and Supported Self-Management) with VA Stepped Usual Care
- Where
- United States
- Volunteers
- 530 people
- Sponsor
- Duke University
Chronic Non-Specific Low Back Pain, Chronic Non-specific Neck Pain
Predictive Variables of Outcome in Subjects With Chronic Rachialgia Referred to Different Pathways of Physiotherapy.
The aim of this study is to investigate the predictive value of various biopsychosocial variables on the outcomes of subjects with chronic spinal pain undergoing public health rehabilitation pathways.
- Trial name
- PRE-CBP (NCT06915896)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Low Back Pain, Depression
Subgroups of Older Adults With Back Pain and Multiple Chronic Conditions
The overall goal of this study is to use the National Health and Aging Trends Study (NHATS) data to gain an understanding of how multiple chronic conditions impact the health outcomes of older adults with back pain.
- Conditions
- Low Back Pain, Depression, Anxiety, Osteoarthritis
- Trial name
- NCT03632122
- Where
- United States
- Volunteers
- 8,344 people, healthy volunteers welcome
- Sponsor
- University of Washington
Medulloblastoma
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
Historically, medulloblastoma treatment has been determined by the amount of leftover disease present after surgery, also known as clinical risk (standard vs. high risk).
- Trial name
- NCT01878617
- Testing
- Craniospinal Irradiation with boost to the primary tumor site, Cyclophosphamide, Cisplatin
- Where
- 23 sites in United States, Australia and 2 more
- Volunteers
- 660 people
- Sponsor
- St. Jude Children's Research Hospital
Low Back Pain, Triage
The Effect of Chiropractor-informed Triage on Low Back Pain Patient Outcomes and Trajectories
Almost everyone will have low back pain (LBP) at some point in their lives. LBP is a complex multifactorial condition for which diagnosis and clinical management remains a challenge.
- Trial name
- NCT04923308
- Testing
- Triage results disclosed, Triage results undisclosed
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- Université du Québec à Trois-Rivières
Low Back Pain
Alberta Back Care Pathway (ABCp)
Every year, the pain, disability, addiction, and expense associated with LBP increase in Alberta. This escalation is largely because most people with LBP seek care from family physicians who are unable to provide effective…
- Trial name
- ABCp (NCT05452876)
- Testing
- ABCp, Usual Care
- Where
- Canada
- Volunteers
- 713 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Low Back Pain, Veterans Family
Improving Veteran Access to Integrated Management of Back Pain
The purpose and objective of this pragmatic trial is to examine the effectiveness of two different quality improvement care pathways for low back pain (LBP); a sequenced, integrated care pathway (ICP) and 2) a coordinated, care…
- Trial name
- AIM-BACK (NCT04411420)
- Testing
- Pain modulation with physical pain treatment, Telephone delivered self-management counseling for increasing physical activity, Telephone delivered behavioral treatment for participants with high risk for continued disability
- Where
- United States
- Volunteers
- 1,817 people
- Sponsor
- Duke University
Failed Back Surgery Syndrome, Chronic Pain
Study on Failed Back Surgery Syndrome Pathway Optimization: A Focus on Patient Identification, Chronicization Factors and Outcome Predictors
This pilot study is part of a global project that aims to better define and understand features of FBSS/POPS "post-operative persistent syndrome patients (shortened as "FBSS" in the following project).
- Trial name
- PREDIBACK (NCT02964130)
- Testing
- No name
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Poitiers University Hospital
Lumbar Radiculopathy, Radicular Low Back Pain
R³ Rehab Pathway Versus Usual Care After Lumbar Radicular Surgery
The R³ trial is a multicentre cluster randomized controlled trial evaluating an evidence-based, person-centred rehabilitation pathway for patients undergoing lumbar surgery for radicular pain.
- Trial name
- R³ (NCT07313566)
- Testing
- R³ Rehabilitation Pathway
- Where
- 16 sites in Belgium
- Volunteers
- 480 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cervical Spondylotic Myelopathy, Ossification of Posterior Longitudinal Ligament in Cervical Region
The Application of Enhanced Recovery After Surgery Clinical Pathway in Posterior Cervical Spine Surgery
This study intends to establish a multidisciplinary collaborative ERAS clinical pathway of cervical posterior surgery,and to verify its effectiveness, safety and value in health economics.
- Trial name
- NCT05149404
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
fMRI, Dorsal Pathway
Brain Stimulation and Vision Testing
Background: -The brain has two systems for recognizing objects. One system recognizes what an object is, and the other system recognizes where the object is located.
- Conditions
- fMRI, Dorsal Pathway, Ventral Pathway
- Trial name
- NCT01617408
- Where
- United States
- Volunteers
- 665 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Low Back Pain
Implementation of P3C-LBP in Swedish Primary Care
The goal of this observational study is to evaluate the implementation of a patient centered coordination care (P3C) pathway for the management of patients with low back pain (LBP) in primary care, in Östergötland health care…
- Trial name
- P3C-LBP (NCT06240533)
- Where
- Sweden
- Volunteers
- 300,000 people
- Sponsor
- Linkoeping University
Arthropathy of Knee
Protocol for a Multicenter Study on (Cost)Effectiveness of the Back At Work After Surgery (BAAS): a Clinical Pathway for Knee Arthroplasty
Background Optimizing return to work (RTW) after knee arthroplasty (KA) is becoming increasingly important due to a growing incidence of KA and poor RTW outcomes after KA.
- Trial name
- NCT05690347
- Testing
- Back At work After Surgery (BAAS)
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Low Back Pain
Personalisation of Prosthetic Care for Lower- Limb Amputees
The global rise in lower-limb amputations is mainly due to diabetes and vascular complications. Amputations cause serious physical and psycho-social disabilities which impair locomotion and compromise patients quality of life.
- Trial name
- NCT06243549
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Bath
Nicotine Dependence
TMS-fMRI for Neural Pathway in Smokers
Cigarette smoking causes significant morbidity and mortality in the United States. Smoking cessation is difficult, with the average smoker attempting to quit five times before permanent success.
- Trial name
- NCT02665338
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Xingbao Li
Chronic Pain, Lumbar Back Pain
Effectiveness of Acupuncture Clinical Pathway
The study will be described the development and implementation of the Clinical pathway (CPW) for acupuncture treatment in the management of patients with some chronic pain conditions.
- Conditions
- Chronic Pain, Lumbar Back Pain, Osteoarthritis, Knee, Headache
- Trial name
- ACUPATHWAY (NCT04490798)
- Testing
- Electroacupuncture
- Where
- Spain
- Volunteers
- 3,245 people
- Sponsor
- Hospital Son Llatzer
Schizophrenia
Evaluation of Dorsal Visual Stream in Patients With Schizophrenia
Schizophrenia patients in comparing to normal controls show decreased ability to identify objects with decreased level of fragmentation, a task that is associated with magnocellular pathway function.
- Trial name
- NCT01378403
- Where
- Israel
- Volunteers
- 22 people
- Sponsor
- Sheba Medical Center
Back Pain, Low
Can we Improve Care Pathway in Low Back Pain?
The general objective of this pilot study is to investigate a new multi-level intervention in primary care to improve the care of patients with low back pain.
- Trial name
- DeltaDos (NCT05768516)
- Testing
- Implementation of best practice for low back pain in primary care
- Where
- 2 sites in Switzerland
- Volunteers
- 124 people
- Sponsor
- University Hospital, Geneva