Clinical trials: Drainage
Pulmonary Air Leaks
Spiration Valves Against Standard Therapy
VAST is a multicenter, prospective, randomized, controlled study designed to evaluate treatment of persistent air leak with the SVS as compared to standard chest tube drainage management and other standard-of-care interventions…
- Trial name
- VAST (NCT02382614)
- Testing
- Spiration Valve System
- Where
- 20 sites in United States
- Volunteers
- 75 people
- Sponsor
- Olympus Corporation of the Americas
Malignant Melanoma
Suction Drain in Axillary Lymph Node Dissection for Malignant Melanoma
Postoperative complications like seroma formation and wound site infection readily occur following completion axillary lymph node dissection (ALND) for malignant melanoma.
- Trial name
- NCT04648163
- Where
- Austria
- Volunteers
- 118 people
- Sponsor
- Medical University of Graz
Chest Injury Trauma
Under Water Seal Versus Negative Pleural Suction in Chest Trauma Patients
:The investigators aim to provide trauma patient with the best and most efficient managment options and long-term stability with the least complications by comparing the effect of under water seal alone of chest tube in one…
- Trial name
- NCT04673084
- Testing
- negative pleural suction
- Volunteers
- 80 people
- Sponsor
- Assiut University
Linear Closure, Surgery
Evaluating the Impact of Video Discharge Instructions for Mohs Surgery Post-Operative Care
The purpose of this research is to look at how educational videos provided by doctors might affect patients knowledge, satisfaction, confidence, and anxiety with post-operative Mohs surgery care.
- Trial name
- NCT02970435
- Testing
- Video Discharge Instructions, Telecommunication Reminders, Standard of Care
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Case Comprehensive Cancer Center
Total Knee Arthroplasty
Low Versus High Pressure Suction Drainage After Total Knee Arthroplasty
Principal hypothesis: A low suction drainage (-50 mmHg) reduce a 25% the blood loss with respect a standard closed drainage (-700 mmHg) following total knee arthroplasty.
- Trial name
- NCT00866268
- Testing
- low pressure suction drainage, High pressure suction drainage
- Where
- 2 sites in Spain
- Volunteers
- 169 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Patient Deterioration, Patient Monitoring
Wireless Assessment of Respiratory and Circulatory Distress - Europe
Hospital patient monitoring in Europe is often intermittent, which can delay detection of clinical deterioration during hospitalization and after discharge.
- Conditions
- Patient Deterioration, Patient Monitoring, Clinical Deterioration
- Trial name
- WARD-EU (NCT07451249)
- Testing
- WARD-CSS (Wireless Assessment of Respiratory and Circulatory Distress - Clinical Support System)
- Where
- 5 sites in Denmark, Netherlands and 2 more
- Volunteers
- 1,240 people, healthy volunteers welcome
- Sponsor
- Eske Kvanner Aasvang
Sepsis
Long-term Assessment of Patients Treated in the ICU for Sepsis
This study is a prospective, observational cohort clinical registry designed to describe clinical and epidemiological characteristics and outcomes of adult patients hospitalized with sepsis.
- Trial name
- LAPTUS (NCT07502794)
- Testing
- Usual Care
- Where
- Brazil
- Volunteers
- 760 people
- Sponsor
- Hospital Israelita Albert Einstein
Glaucoma, Blindness, Acquired
Laminar Drainage Implant: Safety of a Novel Surgical Treatment for Refractory Glaucoma.
Purpose: To assess the feasibility of a surgical technique and present the preliminary safety results of a new glaucoma device devoid of a tube in painful blind eyes.
- Conditions
- Glaucoma, Blindness, Acquired, End-Stage Glaucoma, Glaucoma Traumatic
- Trial name
- NCT03166566
- Testing
- Laminar drainage implant surgery.
- Volunteers
- 15 people
- Sponsor
- Federal University of Minas Gerais
Prostate Cancer
Postoperative Patient Comfort and Quality of Micturition in Suprapubic Tube vs. Transurethral Catheterization After RARP
The purpose of the study is to determine, whether the postoperative quality of micturition and continence can be improved depending on the urinary drainage catheter and retention after robot assisted radical prostatectomy.
- Trial name
- MPH (NCT02812173)
- Testing
- suprapubic tube ex 2 day, suprapubic tube ex 5 day, transurethral catheter ex 5 day
- Where
- Germany
- Volunteers
- 234 people
- Sponsor
- St. Antonius Hospital Gronau
Obstructive Jaundice
Investigating the Efficacy and Safety of the Combination Treatment of Huaier Granule and Biliary Drainage for MOJ
This study is designed to evaluate the efficacy and safety of the combination treatment of Huaier granule and biliary drainage for malignant obstructive jaundice.
- Trial name
- NCT03491254
- Volunteers
- 852 people
- Sponsor
- zhaoyu liu
Analgesia After ED Discharge for Extremity Injuries
Comparing the Efficacy of Oral Opioids for Outpatient Acute Pain Management After ED Discharge Discharge
There will be 3 randomized, double-blinded clinical trials to help determine which of commonly prescribed oral opioid combination is most effective in managing acute extremity pain after discharge from the adult emergency…
- Trial name
- NCT01402375
- Testing
- Hydrocodone (first trial), Codeine (first trial), Oxycodone (for second trial)
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- Montefiore Medical Center
All Conditions Treated at the Heart Centres
DenHeart - Self-reported Health and Quality of Life at Hospital Discharge From a Heart Centre in Denmark
The objective of this study is to describe: 1) Differences in perceived health at hospital discharge between diagnostic groups and in-hospital predicting factors.
- Trial name
- DenHeart (NCT01926145)
- Where
- 5 sites in Denmark
- Volunteers
- 16,712 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Blood Loss, Surgical
Suction Drainage in the Management of Peri-operative Bleeding in Total and Unicomcompartmental Knee Arthroplasty
Although, suction drainage is routinely used in orthopedic clinical practice, there are still no precise guidelines on its use in total joint arthroplasty, particularly in total as well as unicompartmental knee arthroplasty.
- Trial name
- NCT04508101
- Volunteers
- 153 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Jaundice, Obstructive, Klatskin Tumor
Process Optimization of Preoperative Biliary Drainage in Patients With Malignant Obstructive Jaundice
The purpose of this study is to evaluate the safety and effectiveness of different methods of preoperative biliary drainage in patients with extrahepatic bile duct neoplasms with obstructive jaundice (hilar cholangiocarcinoma…
- Trial name
- NCT03527875
- Testing
- PTBD group, ENBD group, EBS group
- Volunteers
- 564 people
- Sponsor
- Shanghai Zhongshan Hospital
Anesthesia; Adverse Effect, Spinal and Epidural
Comparative Study Between Bilateral and Unilateral Spinal Anaesthesia
The purpose of this study is to compare unilateral spinal anesthesia using hyperbaric Prilocaine with "classical bilateral spinal anesthesia" using plain Prilocaine according to block characteristics and quality of micturition…
- Trial name
- NCT01877356
- Testing
- bilateral spinal anesthesia, unilateral spinal anesthesia
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- University Hospital, Antwerp
Premature Birth of Newborn, Family
GPS (Giving Parents Support): Parent Navigation After NICU Discharge
BACKGROUND: Annually >400,000 US newborns require neonatal intensive care unit (NICU) care.1/3 will require ongoing or specialty care after discharge.
- Conditions
- Premature Birth of Newborn, Family, Immature Newborn, Newborn Morbidity
- Trial name
- GPS (NCT02643472)
- Testing
- Parent Navigator, Care Notebook
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Children's National Research Institute
ALL, Adult
Video-recOrded hospItal dischaRge (VOIR)
This study evaluates the suitability and acceptability of video-recorded discharge via the Patient Knows Best app. Through a randomized control trial, patients receive either standard discharge care or standard care supplemented…
- Trial name
- VOIR (NCT06512272)
- Testing
- Video recorded shared using a mobile application
- Volunteers
- 60 people
- Sponsor
- Anglia Ruskin University
Critical Illness
Evaluation of Clinical Implementation of Machine Learning Based Decision Support for ICU Discharge
Unexpected intensive care unit (ICU) readmission is associated with longer length of stay and increased mortality. Bedside decision support may prevent readmission and mortality and may allow optimizing ICU capacity.
- Trial name
- MIRACLE (NCT05497505)
- Testing
- Pacmed Critical
- Where
- 2 sites in Netherlands
- Volunteers
- 1,500 people
- Sponsor
- Patrick J. Thoral
Postoperative Recovery
Esketamine-propofol Versus Propofol for Flexible Bronchoscopy
Bronchoscopy is a promising technology for lung and bronchus disease detection and therapy. However, this procedure is associated with a relatively high risk of hypoxemia, coughing, wheezing, and dyspnea.
- Trial name
- NCT05643066
- Testing
- 0.1 mg/kg esketamine, 0.2 mg/kg esketamine, 0.9% saline
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Fujian Provincial Hospital
Foot Reflexology
Effect of Foot Reflexology on Pain Associated With Mediastinal Chest Drain Removal
Cardiovascular diseases (CVDs) remain the leading cause of death worldwide and significantly affect patient quality of life and socioeconomic status.
- Trial name
- NCT05631522
- Testing
- foot reflexology
- Volunteers
- 80 people
- Sponsor
- Mansoura University