Clinical trials: Drains
Wound Contamination
Prospective Randomised Study for Use of CHG Dressing at Entry Site of EVD's to Reduce EVD-associated Infections
The objective of this study is to assess the efficacy of 3M™ Tegaderm™ CHG I.V. Securement Dressing at the entry-site of a EVD in reducing quantity of microorganisms (CFU/cm2) after a time period of 5 days as a surrogate marker…
- Trial name
- EVDAI (NCT02078830)
- Testing
- 3M™ Tegaderm™ CHG I.V. Securement Dressing
- Where
- Switzerland
- Volunteers
- 57 people
- Sponsor
- University Hospital, Basel, Switzerland
Pancreatic Fistula
Study of Pancreatic Enzymes in the Drains as Early Biomarkers of Post-operative Pancreatic Fistula and Its Clinical Repercussions
Surgery is the principal treatment for benign and malignant pancreatic tumours. This surgery can be accompanied by complications among which the main one is pancreatic fistula, which leads to the flow of pancreatic juices into…
- Trial name
- LIPA-DRAIN (NCT02784990)
- Testing
- Lipase, amylase and CRP (C-reactive protein) dosages
- Where
- 10 sites in France
- Volunteers
- 770 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Breast Cancer, Seroma
Seroma Reduction and Drain Free Mastectomy
To prove that omitting drains after mastectomy and flap fixation does not contribute to higher incidence of seroma formation and therefore reducing patient disutility such as seroma aspirations and visits to the outpatient…
- Conditions
- Breast Cancer, Seroma, Wound Complication
- Trial name
- SARA (NCT04035590)
- Testing
- No drain, With drain
- Where
- Netherlands
- Volunteers
- 250 people
- Sponsor
- Zuyderland Medisch Centrum
Cerebrospinal Fluid Drainage
Evaluation of Outcomes Related to Cerebrospinal Fluid Drain Placement
The purpose of this study is to compare the rate and severity of complications associated with CSFD placement either with or without fluoroscopic guidance.
- Trial name
- NCT04505423
- Testing
- Blind CSF Drain Placement, Fluoroscopy-guided Drain Placement
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- University of North Carolina, Chapel Hill
Seroma
Arista for ALT Donor Sites to Reduce Drain Output
This is a single-blinded multi-institutional randomized controlled trial to evaluate the effectiveness of Arista hemostatic matrix powder (Arista® AH, C. R. Bard, Inc.
- Trial name
- NCT02477774
- Testing
- ARISTA
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Ascites Hepatic
Prospective Evaluation of PleurX Drain for Treatment of Cirrhotic Refractory Ascites
Refractory ascites (fluid build up in the abdomen that can not bet managed by medications) occurs in at least 10% of patients with end stage liver disease (cirrhosis).
- Trial name
- NCT04569565
- Testing
- PleurX catheter
- Volunteers
- 12 people
- Sponsor
- University of Alberta
Presence of Ileostomy
Need for Subcutaneous Wound Drains in Ileostomy Reversal
The purpose of this study is to find out whether the insertion of subcutaneous wound drains has an influence on postoperative hospital stay in ileostomy reversal.
- Trial name
- DRASTAR (NCT01050686)
- Testing
- insertion of subcutaneous wound drain, no insertion of subcutaneous wound drain
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- Charite University, Berlin, Germany
Subdural Hematoma
Augmented Reality for Subdural Drain Placement
This study involves using a augmented reality (AR) system to assist in the placement of a subdural evacuating portal system (SEPS).
- Trial name
- NCT06052124
- Testing
- Augmented Reality Device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Perforated Peptic Ulcer, Fast Track Surgery
Impact of Abdominal Drains on the ERAS Pathway in Peptic Perforation
This study plans to assess the effect of placement of abdominal drains on the outcomes of ERAS (Enhanced recovery after surgery) protocol in the perioperative management of peptic perforation.
- Conditions
- Perforated Peptic Ulcer, Fast Track Surgery, Perforated Bowel, Post-Op Complication
- Trial name
- TUBELESS (NCT05368233)
- Testing
- ERAS protocol
- Where
- India
- Volunteers
- 92 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Aneurysm, Ruptured, Hyperglycemia
Shunt-dependency After aSAH - Role of Early Hyperglycaemia in CSF and Blood
The goal of this study is to confirm the association of early increased glucose levels in cerebro-spinal fluid (CSF) and ventriculo-peritoneal-shunt (VPS)-dependency also evaluating the influence of blood glucose on VPS…
- Conditions
- Aneurysm, Ruptured, Hyperglycemia, Hydrocephalus
- Trial name
- HCP-Glc (NCT06486909)
- Testing
- Cerebrospinal Fluid (CSF) Sample, Blood Serum Sample
- Where
- 3 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Isabel Hostettler
Cesarean Section
Subcutaneous Drains And Cesarean Section
A randomized controlled trial that aimed at studying the values (if any) of subcutaneous drains use in lean women during Cesarean section.
- Trial name
- NCT03114332
- Testing
- Subcutaneous Drain
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Menoufia University
Subarachnoid Hemorrhage.
Use of Lumbar Drain to Remove Clots in Patients Admitted to the Neuro-ICU After Subarachnoid Hemorrhage.
Recently, a clinical trial showed that the use of lumbar drains compared to ventricular drain in patients suffering from subarachnoid hemorrhage resulted in less delayed ischemic neurological deficits but failed to show a…
- Trial name
- NCT01886521
- Testing
- Lumbar drain, Ventricular drain
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Acute Ischemic Stroke
Effects of Cerebrospinal Fluid Drainage on Cerebral Hemodynamics
This pilot interventional study investigates whether continuous cerebrospinal fluid (CSF) drainage via lumbar drain can improve cerebrovascular reactivity (CVR) in patients with acute ischemic stroke and hemodynamic failure, as…
- Trial name
- NCT07056907
- Testing
- Lumbar drain placement
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Safety Issues
he Safety Research of Timing of the Removal of Abdominal Drains After Pancreatic Surgery
Randomized, open, single-center, controlled prospective studies were designed to obtain reliable level I evidence in evidence-based medicine.Based on the premise of at least a 6-fold reduction in pancreatic fistula, as observed…
- Trial name
- NCT04892615
- Testing
- drainage tube was removed on 5th days after surgery., drainage tube was removed on 7th days after surgery.
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Xian-Jun Yu
Hematoma Intracranial, Hydrocephalus
Subgaleal Drains in Decompressive Craniectomies
This research is about the use of subgaleal drains to prevent accumulation of blood under the skin in patients undergoing surgery to remove part of the skull(craniectomy) and its associated complications.
- Conditions
- Hematoma Intracranial, Hydrocephalus, Surgical Site Infection, Wound Breakdown
- Trial name
- VADER (NCT03777774)
- Testing
- Passive Redon subgaleal drains, Vacuum Redon subgaleal drains, No Redon subgaleal drains
- Where
- 2 sites in Malaysia
- Volunteers
- 78 people
- Sponsor
- Universiti Sains Malaysia
Pancreaticoduodenectomy, Distal Pancreatectomy
Randomized Controlled Trial Comparing Closed-suction Drain Versus Passive Gravity Drain Following Pancreatic Resection
Pancreatic resection is the only potentially curative modality of treatment for pancreatic neoplasm. The mortality associated with this procedure decreased rapidly in the past decades.
- Trial name
- DRAPA (NCT01988519)
- Testing
- Closed gravity drain, closed suction drain
- Where
- 2 sites in Czechia
- Volunteers
- 223 people
- Sponsor
- University Hospital Hradec Kralove
Colorectal Cancer, Diverticulitis
A T Drain Approach Treating Anastomotic Leaks After Gastrointestinal Surgery
Assessing the use of a T drain approach for an anastomotic leak after gastrointestinal surgery. The study's aim is to retrospectively assess the safety and benefits of this approach.
- Trial name
- TDRAIN (NCT03974672)
- Testing
- Re-laparotomy
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Breast Cancer
Quilting Sutures After Mastectomy
The use of wound drains after mastectomy is common practice in Belgium. However, placement of suction drainage has several disadvantages.
- Trial name
- BE-Quilt (NCT06415032)
- Testing
- Mastectomy with Quilting sutures without drain placement, Mastectomy with Conventional sutures with drain placement
- Where
- Belgium
- Volunteers
- 296 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Breast Cancer
Drain-Less Abdominally Based Breast Reconstruction Using Lysine-Derived Urethane Adhesive
Drains are routinely utilized in breast reconstruction when using abdominal tissue of the patient to remove fluid buildup while the body heals after surgery.
- Trial name
- NCT03159598
- Testing
- Tissue Glu, Drain, Questionnaires
- Sponsor
- Case Comprehensive Cancer Center
Pleural Effusion
A Feasibility and Safety Study of the Use of a Dedicated Ballooned Intercostal Drain
Drainage of air and fluid from the chest cavity using plastic tubes (chest drains) is an essential tool in Chest Medicine. A common complication of drain insertion is accidental removal of the drain, usually as a result of…
- Trial name
- NCT01869504
- Testing
- Balloon-tipped intercostal drain
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Sherwood Forest Hospitals NHS Foundation Trust