Clinical trials: Drains
Seroma Following Procedure, Infections
Single Versus Double Drains in the Axillary and Pectoral Regions After Modified Radical Mastectomy
Normally, after this surgery, skin is stitched in the usual simple way, with no quilting, and two drains are put in to remove serosa, one under the arm and one on the chest.
- Conditions
- Seroma Following Procedure, Infections, Pain, Postoperative
- Trial name
- SVDD (NCT07512141)
- Testing
- Double drains will be placed, A single drain will be placed
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Seroma, Hernia, Inguinal
Use of Diathermy Versus Blunt Dissection in TEP for Inguinal Hernia
There is a long debate whether monopoloar or blunt dissection should be adopted in TEP to minimise the chance of seroma formation.
- Trial name
- NCT03665883
- Testing
- Monopolar energy, Blunt dissection
- Where
- China
- Volunteers
- 103 people
- Sponsor
- The University of Hong Kong
Pancreas; Fistula
Impact of Highest Drain Fluid Amylase Levels on Surgical Outcomes and Postoperative Interventions in Patients Undergoing Pancreaticoduodenectomy
This study investigated the impact of highest drain fluid amylase (DFA) level on postoperative pancreatic fistula (POPF) severity and outcomes of patients undergoing pancreaticoduodenectomy (PD) with POPF.
- Trial name
- NCT04448795
- Volunteers
- 600 people
- Sponsor
- Chang Gung Memorial Hospital
Pharmacokinetics
Pharmacokinetics of Ceftolozane/Tazobactam in Plasma and Cerebrospinal Fluid
Ceftolozane/tazobactam is an emerging newly available antibiotic that has a broad spectrum of activity, and could be potentially useful in the management of central nervous system infections.
- Trial name
- NCT03309657
- Testing
- Ceftolozane/tazobactam
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Royal Brisbane and Women's Hospital
in Situ Breast Cancer, Invasive Breast Cancer
Suction Drain Versus the Use of Adaptive Skin Sutures After Mastectomy ± Axillary Lymphadenectomy; a Prospective Randomised Study
The objective of this prospective randomized study is to perform qualitative and quantitative comparisons between the insertion of traditional suction drains (Arm: Suction drain) versus the application of absorbable adaptive…
- Trial name
- NCT01509781
- Testing
- Insertion of suction drain(s) following mastectomy, Adaptive skin sutures.
- Where
- Hungary
- Volunteers
- 400 people
- Sponsor
- National Institute of Oncology, Hungary
Surgical Site Infection
SSI Rates in Patients Undergoing Mastectomy Without Reconstruction- A Multicenter, Double-blinded RCT.
Breast cancer is the second most prevalent malignancy in the world and an important component of treatment warrants surgical procedures such as mastectomy.
- Trial name
- NCT04577846
- Testing
- Cephalexin 500 MG
- Where
- 3 sites in Pakistan
- Volunteers
- 384 people
- Sponsor
- Aga Khan University
Goiter
Is the Use of Drain for Thyroid Surgery Realistic?
Background : The use of suction drains in thyroid surgery is common practice in order to avoid haematoma or seroma, as well as to identify promptly the onset of haemorrhaging that might compromise the patient's airway.
- Trial name
- NCT01771523
- Testing
- Thyroidectomy, use of drain
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Acute Breast Abscess
Comparison of Standard Incision and Drainage Versus Percutaneous Suction Drainage in the Management of Acute Breast Abscess
This prospective interventional study compares the effectiveness of standard incision and drainage versus percutaneous suction drain placement in the management of acute pyogenic breast abscess.
- Trial name
- I&D VS PSD (NCT07588412)
- Testing
- Incision and Drainage, Percutaneous Suction Drain
- Where
- India
- Volunteers
- 80 people
- Sponsor
- GSVM Medical College
Pain, Postoperative, Breast Cancer
Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain
in this study we are investigating the role of instillation of Bupivacaine through surgical drains at the end of mastectomy surgeries in controlling post operative pain and decreasing their pain killers requirement in the early…
- Trial name
- NCT03799757
- Testing
- 40ml of 0.25% bupivacaine, 40ml of 0.9% normal saline
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Alexandria University
Surgical Site Infections
Antibiotic Prophylaxis in Prosthetic Breast Reconstructions
The added benefit of prolonged antibiotic prophylactic treatment in patients undergoing breast reconstruction who have drains placed for several days after surgery is controversial.
- Trial name
- NCT02012517
- Testing
- Prolonged antibiotic treatment, Short antibiotic course (standard of care)
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Sheba Medical Center
ACDF Surgery
Post-operative Outcomes of Anterior Cervical Discectomy and Fusion Surgery With and Without Drain Placement
Anterior Cervical Discectomy and Fusion (ACDF) is a widely performed surgical procedure used to treat cervical spondylosis and cervical disc herniations with cervical nerve root compression and or cervical spinal cord compression…
- Trial name
- NCT06938607
- Testing
- Drain
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Nebraska
ICH - Intracerebral Hemorrhage, IVH- Intraventricular Hemorrhage
Placing External Ventricular Drains Using Assistive Augmented Reality or Image-Based Localization
The goal of this clinical trial is to assess if EVD placement using augmented reality is non inferior to image-guidance systems for assistance in adult patients needing an EVD for spontaneous ICH with IVH or severe TBI.
- Conditions
- ICH - Intracerebral Hemorrhage, IVH- Intraventricular Hemorrhage, TBI Traumatic Brain Injury
- Trial name
- PEARL (NCT07042048)
- Testing
- EVD placement - image-guidance assisted, EVD placement - AR assisted
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cooper Health System
Cancer, Breast
Prospective Clinical Investigation Comparing Standard Wound Closure Technique With Drains (Control) to Standard Wound Closure Techniques With TissuGlu® and No Drains (Test) in Mastectomy
Comparing standard wound closure technique with drains (control) to standard wound closure techniques with TissuGlu® and no drains (test) in mastectomy
- Trial name
- NCT02958449
- Testing
- Test - Standard Closure with TissuGlu Surgical Adhesive
- Where
- 10 sites in Germany, United Kingdom
- Volunteers
- 77 people
- Sponsor
- Cohera Medical, Inc.
Surgical Site Infection
Protocol Effect of Negative Pressure Drain to Reducing Surgical Site Infection in Surgical Wound of Abdominal Surgery
Surgical site infection (SSI) is one of main complication in surgery. It usually occurs within 30 days post operation. The superficial SSI is an infection of skin and subcutaneous layer, clinically presented by pus oozing.
- Trial name
- NCT05865821
- Testing
- Negative pressure drainage, No pressure drain
- Where
- Thailand
- Volunteers
- 130 people
- Sponsor
- Mahidol University
Arthroplasty, Replacement, Knee
Effect of Suction Drains in Total Knee Arthroplasty With Tranexamic Acid
Problem Suction drains during TKA present certain costs to the health system and requires additional nursing care. There is no clear evidence that supports their use, and no studies so far have compared blood loss in patients…
- Trial name
- NCT03145493
- Testing
- drainage
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pleura; Effusion, Esophageal Adenocarcinoma
Outcomes of a Single Chest Drain vs Two Drains
Esophagectomy is a major surgical procedure done for carcinoma of esophagus. Usually bilateral chest tubes are placed in surgery for prevention of fluid accumulation in chest.
- Conditions
- Pleura; Effusion, Esophageal Adenocarcinoma, Esophageal Anastomotic Leak
- Trial name
- NCT07125248
- Testing
- Bilateral chest tube placement, Single drain placement
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Khyber Teaching Hospital
Breast Reconstruction, Breast Cancer
Comparison of PEAK PlasmaBlade™ to Conventional Diathermy in Abdominal Based Free Flap Breast Reconstruction
Electrosurgery allows for dissection with simultaneous haemostasis. One of its disadvantages is that the heat production can cause injury to the surrounding tissue which may result in wound healing problems and an increased rate…
- Trial name
- NCT04350411
- Testing
- Conventional diathermy, PEAK PlasmaBlade™
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Anglia Ruskin University
Prostate Cancer
Non-inferiority Trial Omitting Drainage After Robot-assisted Radical prostatectomY
This is a multicenter, prospective, randomized, controlled, open-label, assessor-blinded, non-inferiority trial evaluating whether pelvic drainage can be safely omitted after robot-assisted radical prostatectomy (RARP).
- Trial name
- POND-RARP (NCT07887321)
- Testing
- No Pelvic Drain Placement, Pelvic Drain Placement
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Shanghai East Hospital
Critical Illness, Burns
Effect of Active Drain Line Clearance on Catheter-Associated Bacteriuria
Catheter-associated urinary tract infections (CAUTI) are the most common nosocomial infections in critically ill patients and are responsible for high morbidity rates, increased hospital stays and associated costs.
- Conditions
- Critical Illness, Burns, Surgery, Urinary Tract Infections
- Trial name
- CAB (NCT03816384)
- Testing
- Standard of Care, DLC Group, DLCS Group
- Sponsor
- Potrero Medical
Paraumbilical Hernia
Comparison of Extended Totally Extra-peritoneal Repair (ETEP) and Subcutaneous On-lay Endoscopic Approach (SCOLA) for Para-umbilical Hernia (PUH).
The goal of this clinical trial is to learn if one of two surgical techniques works better for treating paraumbilical hernias in adult men and women between 18 and 65 years old.
- Trial name
- NCT07434687
- Testing
- Extended Totally Extra Peritoneal Repair, Subcutaneous On-Lay Endoscopic Approach
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- King Edward Medical University