Clinical trials: Dreams
Rheumatoid Arthritis
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Tofacitinib vs Abatacept
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- DREAM (NCT04529876)
- Testing
- Tofacitinib, Abatacept
- Where
- United States
- Volunteers
- 29,464 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Chronic Obstructive Pulmonary Disease
Dream Analysis in COPD Patients
Sleep is a fundamental period in life. In a previous work, the investigators have shown that COPD patients presented on the EEG figures found in patients with chronic pain: Alpha-Delta.
- Trial name
- Rêve BPCO (NCT05263349)
- Testing
- Typical Dreams Questionnaire, HAD Questionnaire, Dream Booklet
- Where
- France
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sleep Disturbance, Mental Health Issue
Sweet Scents to Sweet Dreams
The purpose of this study is to determine the effect of herbal pillows on sleep and quality of life in a healthy population using actigraphy, validated questionnaires and daily diary logs.
- Trial name
- SSS (NCT06247696)
- Testing
- Herbal Pillows
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Hypertension
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Amiloride vs Triamterene
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- NCT05125237
- Testing
- Amiloride, Triamterene
- Where
- United States
- Volunteers
- 155,963 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Impaired Glucose Tolerance, Cardiovascular Disease
The DREAM (Diabetes Reduction Assessment With Ramipril and Rosiglitazone Medication) Trial
The purpose of this study is to determine if ramipril and/or rosiglitazone prevent the onset of type 2 diabetes.
- Conditions
- Impaired Glucose Tolerance, Cardiovascular Disease, Glucose Metabolism Disorders
- Trial name
- NCT00095654
- Testing
- Ramipril, Rosiglitazone
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Gerstein, Hertzel, MD
Cancer
Discovering Cancer Risks From Environmental Contaminants and Maternal/Child Health
The DREAM Cohort is a longitudinal observational study developed to enhance our understanding of how multiple exposures to environmental chemicals and pollutants across a diverse population of pregnant women and their offspring…
- Trial name
- NCT05746169
- Testing
- Health Questionnaires, Specimen sample collection
- Where
- 3 sites in United States
- Volunteers
- 1,576 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Head Injury, Sport Injury
Dynamic Vision Testing and Concussion Management Dream Team 65
The purpose of this study is to determine the value of including dynamic vision testing into California State University, Northridge (CSUN) Athletics' established concussion protocol.
- Conditions
- Head Injury, Sport Injury, Concussion, Brain
- Trial name
- NCT05326555
- Testing
- Dynamic Vision Testing (Bertec Vision Advantage System) and Balance Error Scoring System
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- California State University, Northridge
Sleep, Morning Alertness
Investigating the Effects of Dairy Phospholipids on Sleep and Daytime Function in Healthy Adults.
The aim of the study is to investigate the effects of 6- and 12- week supplementation of a bioactive whey protein concentrate drink containing dairy phospholipids on sleep and daytime function parameters in healthy adults.
- Conditions
- Sleep, Morning Alertness, Evening Alertness, Diurnal Cortisol
- Trial name
- NCT06663865
- Testing
- Active
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Rheumatoid Arthritis
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Tocilizumab vs Abatacept
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- DREAM (NCT04529863)
- Testing
- Tocilizumab, Abatacept
- Where
- United States
- Volunteers
- 30,432 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Anastrozole vs Exemestane/Letrozole
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- NCT05635357
- Testing
- Anastrozole, Exemestane/Letrozole
- Where
- United States
- Volunteers
- 16,989 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Dream Disorder
Prevalence of a Phenomenon of Epic Dream Disorder
A single-center, cross-sectional, non-interventional study based on the sleep department of the Kozhevnikov Clinic for Nervous Diseases at Sechenov University. A.Y.
- Trial name
- NCT05872594
- Testing
- Online questionnaire
- Where
- Russia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Parenting Stress, Mental Health
Development & Validation of a Life Balance Program for Parents of Preschoolers: A Pilot Study
This study aims to examine the relationships among life balance, parenting stress, and mental health in parents of preschool children, and to develop an individualized life balance promotion program for this population.
- Conditions
- Parenting Stress, Mental Health, Occupational Balance
- Trial name
- NCT07669896
- Testing
- Occupational Balance Promotion Program
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
HIV/AIDS, HIV Prevention
Tenofovir Rectal Douche to Prevent HIV Transmission Among Adolescents (ATN DREAM)
ATN DREAM is an early phase-1, open label study to examine the safety, pharmacokinetics (PK), pharmacodynamics (PD), and acceptability of a one-dose tenofovir (TFV) medicated douche.
- Trial name
- NCT04686279
- Testing
- Tenofovir Douche
- Where
- 3 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Healthy Volunteers
Induction of Dreaming With EEG and Anesthesia in Healthy Adults
This open-label, randomized crossover study in healthy adults tests two propofol protocols to produce distinct experiential states.
- Trial name
- IDEA (NCT07198711)
- Testing
- Propofol - Emergence-from-LOR Protocol, Propofol - Light Sedation Protocol
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Stanford University
Glaucoma Patients, Retina Patients
Performance Evaluation of Dream OCT: AP Study
This study will evaluate the clinical performance of a new swept-source OCT imaging device, the VG200D, and to evaluate substantial equivalence with a predicate device, the Cirrus 5000.
- Conditions
- Glaucoma Patients, Retina Patients, Eyes With Corneal Abnormality, Normal Healthy Eyes
- Trial name
- NCT07355491
- Testing
- This is an observational study only, all patients are imaged on the investigational device
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Intalight, Inc
Multiple Sclerosis
DreaMS - Validation Study 1
Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) causing focal lesions of demyelination and diffuse neurodegeneration in the grey and white matter of the brain and spinal cord, leading…
- Trial name
- NCT05009160
- Testing
- dreaMS App R2.1
- Where
- 6 sites in Switzerland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Research Center for Clinical Neuroimmunology and Neuroscience Basel
Psychedelic Effects in Healthy Volunteers
Psilocybin Administration With 5-HT1a Blockade
The purpose of this study is to assess the effects of 5-HT1A receptor blockade on the acute subjective effects of psilocybin, as measured through subjective survey measures and acute electroencephalography (EEG).
- Trial name
- PsilBlock1 (NCT07565493)
- Testing
- Pindolol, Psilocybin
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Competency, Confidence, Self
The DREAM-VR Study: Does a Virtual Reality Tool Help Dental Students Master Acute Medical Emergencies Better?
The goal of this prospective educational cross-over study is to compare the competency and self-reported confidence in managing acute medical emergencies in fourth year dental students at the Academic Centre for Dentistry (ACTA)…
- Conditions
- Competency, Confidence, Self, Medical Emergency Calls, Dentistry
- Trial name
- DREAM-VR (NCT07811349)
- Testing
- DentEmergencyVR tool, Mannikin group
- Where
- Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Denise van Diermen
Diabetes
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Semaglutide v DPP4 Inhibitors
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- NCT05768945
- Testing
- Semaglutide, DPP-4 inhibitor
- Where
- United States
- Volunteers
- 742,670 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Rheumatoid Arthritis
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Methotrexate vs Hydroxychloroquine
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- NCT04691505
- Testing
- Methotrexate, Hydroxychloroquine
- Where
- United States
- Volunteers
- 133,553 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital