Clinical trials: Dreams
Multiple Sclerosis
DreaMS - Validation Study 1
Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) causing focal lesions of demyelination and diffuse neurodegeneration in the grey and white matter of the brain and spinal cord, leading…
- Trial name
- NCT05009160
- Testing
- dreaMS App R2.1
- Where
- 6 sites in Switzerland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Research Center for Clinical Neuroimmunology and Neuroscience Basel
Impaired Glucose Tolerance, Cardiovascular Disease
The DREAM (Diabetes Reduction Assessment With Ramipril and Rosiglitazone Medication) Trial
The purpose of this study is to determine if ramipril and/or rosiglitazone prevent the onset of type 2 diabetes.
- Conditions
- Impaired Glucose Tolerance, Cardiovascular Disease, Glucose Metabolism Disorders
- Trial name
- NCT00095654
- Testing
- Ramipril, Rosiglitazone
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Gerstein, Hertzel, MD
Breast Cancer
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Anastrozole vs Exemestane/Letrozole
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- NCT05635357
- Testing
- Anastrozole, Exemestane/Letrozole
- Where
- United States
- Volunteers
- 16,989 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Healthy Volunteers
Induction of Dreaming With EEG and Anesthesia in Healthy Adults
This open-label, randomized crossover study in healthy adults tests two propofol protocols to produce distinct experiential states.
- Trial name
- IDEA (NCT07198711)
- Testing
- Propofol - Emergence-from-LOR Protocol, Propofol - Light Sedation Protocol
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Stanford University
Diabetes
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Semaglutide v DPP4 Inhibitors
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- NCT05768945
- Testing
- Semaglutide, DPP-4 inhibitor
- Where
- United States
- Volunteers
- 742,670 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Neuroscience of Dreaming, Healthy
The Impact of the Opiate Antagonist Naltrexone on the Emotional Valence of Dreams
In this study, the investigators pose the question which influence the opioid circuit has on positive valent situations in dreams.
- Trial name
- NCT02792140
- Testing
- Naltrexone
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Bern
Psychedelic Effects in Healthy Volunteers
Psilocybin Administration With 5-HT1a Blockade
The purpose of this study is to assess the effects of 5-HT1A receptor blockade on the acute subjective effects of psilocybin, as measured through subjective survey measures and acute electroencephalography (EEG).
- Trial name
- PsilBlock1 (NCT07565493)
- Testing
- Pindolol, Psilocybin
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Chronic Heart Failure
Randomized Controlled Trial of Home Telemonitoring for Elderly People
The DREAMING clinical trial is part of the DREAMING project, which has the objective to demonstrate that the DREAMING platform consisting of integrated health monitoring, alarm handling and videoconferencing services produces…
- Conditions
- Diabetes Mellitus, Chronic Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- Dreaming (NCT00893685)
- Testing
- Wireless monitors for disease specific clinical parameters.
- Where
- 6 sites in Denmark, Estonia and 4 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Health Information Management, Belgium
Chronic Obstructive Pulmonary Disease
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Salbutamol vs Long-acting Muscarinic Antagonists
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- NCT05457868
- Testing
- Salbutamol, LAMA
- Where
- United States
- Volunteers
- 124,117 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Disturbance, Mental Health Issue
Sweet Scents to Sweet Dreams
The purpose of this study is to determine the effect of herbal pillows on sleep and quality of life in a healthy population using actigraphy, validated questionnaires and daily diary logs.
- Trial name
- SSS (NCT06247696)
- Testing
- Herbal Pillows
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Blood Pressure, Sleep
Multidimensional Sleep Health Intervention for Couples
The goal of this pilot dyadic study is to adapt a multidimensional sleep health (MDSH) intervention, previously disseminated at the individual level, for relationship partners, determine whether it improves sleep health and…
- Conditions
- Blood Pressure, Sleep, Cardiovascular Health
- Trial name
- DREAM-COUPLES (NCT07603245)
- Testing
- Multidimensional Sleep Health Promotion Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Columbia University
Schizophrenia and Other Psychotic Disorders, Healthy Adult
Dysfunction of Respiratory Enzymes in Adults With Mental Illness (DREAM)
This study tested whether intravenous methylene blue changes brain activity during a working-memory task differently in adults with schizophrenia taking stable antipsychotic medication and healthy volunteers.
- Trial name
- DREAM (NCT07866833)
- Testing
- Methylene Blue
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- King's College London
Rheumatoid Arthritis
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Tocilizumab vs Abatacept
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- DREAM (NCT04529863)
- Testing
- Tocilizumab, Abatacept
- Where
- United States
- Volunteers
- 30,432 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hypertension
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Amiloride vs Triamterene
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- NCT05125237
- Testing
- Amiloride, Triamterene
- Where
- United States
- Volunteers
- 155,963 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
REM Sleep Behavior Disorder
Prodromal Markers in Recurrent Dream Enactment Behaviors Without REM Sleep Without Atonia
REM sleep behavior disorder is a novel and distinct parasomnia characterized by recurrent dream enactment behaviors (DEBs) and REM sleep without atonia (RSWA) during polysomnographic assessment, with a male predominance and…
- Trial name
- NCT05353881
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Competency, Confidence, Self
The DREAM-VR Study: Does a Virtual Reality Tool Help Dental Students Master Acute Medical Emergencies Better?
The goal of this prospective educational cross-over study is to compare the competency and self-reported confidence in managing acute medical emergencies in fourth year dental students at the Academic Centre for Dentistry (ACTA)…
- Conditions
- Competency, Confidence, Self, Medical Emergency Calls, Dentistry
- Trial name
- DREAM-VR (NCT07811349)
- Testing
- DentEmergencyVR tool, Mannikin group
- Where
- Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Denise van Diermen
Chronic Obstructive Pulmonary Disease
Dream Analysis in COPD Patients
Sleep is a fundamental period in life. In a previous work, the investigators have shown that COPD patients presented on the EEG figures found in patients with chronic pain: Alpha-Delta.
- Trial name
- Rêve BPCO (NCT05263349)
- Testing
- Typical Dreams Questionnaire, HAD Questionnaire, Dream Booklet
- Where
- France
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dream Disorder
Prevalence of a Phenomenon of Epic Dream Disorder
A single-center, cross-sectional, non-interventional study based on the sleep department of the Kozhevnikov Clinic for Nervous Diseases at Sechenov University. A.Y.
- Trial name
- NCT05872594
- Testing
- Online questionnaire
- Where
- Russia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Primary Adrenal Insufficiency, Secondary Adrenal Insufficiency
Dual RElease Hydrocortisone Versus conventionAl Glucocorticoid replaceMent Therapy in Hypocortisolism (DREAM)
This is a randomized, controlled, open, three-armed, multi-centre study designed to compare the effects of dual-release hydrocortisone preparations versus conventional glucocorticoid therapy on anthropometric parameters…
- Trial name
- DREAM (NCT02277587)
- Testing
- Plenadren, Conventional glucocorticoid therapy
- Where
- Italy
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Sleep, Postpartum Depression
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Insufficient and disrupted sleep are rarely addressed in expectant and new mothers, despite evidence that disturbed sleep is a modifiable risk factor for negative health outcomes for mothers and their children.
- Conditions
- Sleep, Postpartum Depression, Pregnancy Related, Insomnia
- Trial name
- NCT06737055
- Testing
- Education about behavioral strategies to improve sleep
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital