Clinical trials: Drinking
Alcohol Consumption, PrEP Uptake
Enhancing HIV Prevention and Reducing Alcohol Use Among People Receiving STI Care in Lilongwe, Malawi
Purpose: To evaluate short-term efficacy and implementation of Treat4All, an alcohol reduction evidence-based intervention, for decreasing heavy drinking and optimizing HIV outcomes (viral suppression among People with HIV (PWH)…
- Conditions
- Alcohol Consumption, PrEP Uptake, Recent Heavy Drinking, HIV Prevention
- Trial name
- Treat4All (NCT06668363)
- Testing
- Treat4All, Standard of care (control arm)
- Where
- Malawi
- Volunteers
- 130 people
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol Use Disorder
Study of Sunobinop on Alcohol Consumption in Alcohol Use Disorder
The purpose of this study is to evaluate the efficacy of sunobinop compared to placebo on alcohol consumption in subjects with alcohol use disorder.
- Trial name
- NCT06545916
- Testing
- Sunobinop
- Where
- 7 sites in United States, Romania
- Volunteers
- 209 people
- Sponsor
- Knoa Pharma LLC
Healthy
Safety, Tolerability and Pharmacokinetics of BI 44370 TA Oral Drinking Solution in Healthy Male Volunteers
To evaluate the safety, tolerability and pharmacokinetics of single rising oral doses of BI 44370 TA in healthy male volunteers, to compare a drinking solution vs.
- Trial name
- NCT02215018
- Testing
- BI 44370 TA solution, BI 44370 TA tablet
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Diarrhea
Solar Water Disinfection Intervention Trial in Bolivia
The importance of waterborne gastrointestinal illness throughout the developing world, the existence of a cheap and effective intervention (SODIS), the concurrent limited dissemination program for SODIS, the need for a controlled…
- Trial name
- SODIS_Bolivia (NCT00731497)
- Testing
- Solar Water Disinfection (SODIS)
- Where
- 2 sites in Bolivia
- Volunteers
- 1,163 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Postpartum Depression (PPD), Alcohol Use
Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms.
- Conditions
- Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
- Trial name
- MOMS-AD (NCT07485036)
- Testing
- Contingency Management & Problem Solving Therapy, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois at Chicago
HIV Infection
Clinical Trial to Reduce Drinking in Women With HIV
The primary objective of this study is to evaluate whether an intervention that involves the medication naltrexone, will reduce drinking and improve health outcomes in women with HIV infection and hazardous drinking.
- Trial name
- WHATIF (NCT01625091)
- Testing
- Naltrexone
- Where
- 2 sites in United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Florida
Driving While Intoxicated, Driving Under the Influence
A Web Application to Reduce Heavy Drinking in First-time DWI Offenders
The overall objective of this project is to develop, evaluate, and disseminate a web application for first-time DWI offenders that will provide them with an age-appropriate brief motivational intervention (BMI) to motivate them…
- Conditions
- Driving While Intoxicated, Driving Under the Influence, Heavy Drinking, Alcohol Abstinence
- Trial name
- NCT02071836
- Testing
- Right Turns web application, Treatment as usual
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Behavior Therapy Associates, LLP
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Consumption
Pilot of an Intervention to Reduce Alcohol Use and Improve ART Adherence Among Men Living With HIV With Pregnant Partners in Uganda.
Hazardous alcohol use, which is common among men in Uganda, is a primary driver of both HIV risk and intimate partner violence (IPV) in this setting.
- Trial name
- Kisoboka Amaka (NCT06900634)
- Testing
- Kisoboka Amaka, Screening and Referral
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- San Diego State University
Bladder Cancer, Smoking
Intensive Smoking and Alcohol Cessation Intervention in Bladder Cancer Surgery Patients
Radical cystectomy provides the best cancer-specific survival for muscle-invasive urothelial cancer. However the postoperative morbidity remains at 11-68 %.
- Conditions
- Bladder Cancer, Smoking, Alcohol Consumption
- Trial name
- STOP-OP (NCT02188446)
- Testing
- Educational programme for smoking and alcohol cessation
- Where
- Denmark
- Volunteers
- 105 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Alcohol Drinking
Imaging Glutamate Release From Alcohol
The goal of this research project is to determine the sensitivity of PET radioligands specific for targets in the glutamate system to an alcohol challenge.
- Trial name
- NCT04159688
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Consumption
Health Behavior Change for Hospitalized Veterans
Veterans drink, binge drink, and drive under the influence of alcohol at higher rates than non-Veterans do. Addressing alcohol misuse, the range of alcohol consumption from risky drinking to alcohol abuse and alcoholism, is a…
- Trial name
- NCT01602172
- Testing
- Brief Alcohol Intervention, Lifestyle brochures
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- VA Office of Research and Development
Pancreatitis, Alcohol Drinking
Continuous Alcohol Monitoring for Pancreatitis
The purpose the research is to demonstrate the feasibility of using a transdermal alcohol sensing device (BACtrack Skyn), and to correlate biological and self-reported alcohol measures with the transdermal alcohol measures in…
- Trial name
- CAMP (NCT04350996)
- Testing
- Wearable alcohol sensor
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Cedars-Sinai Medical Center
Alcohol Abuse, Alcohol Use Disorder
Skills-training for Reducing Risky Alcohol Use in App Form
This study evaluates the efficacy of a skills training web-based mobile phone application, Telecoach among individuals in the general population seeking help for their risky alcohol consumption on the Internet.
- Conditions
- Alcohol Abuse, Alcohol Use Disorder, Alcohol Drinking, Alcohol Dependence
- Trial name
- NCT03696888
- Testing
- Telecoach, TeleCoach control
- Where
- Sweden
- Volunteers
- 678 people
- Sponsor
- Karolinska Institutet
Alcohol Dependence, Alcohol Abuse
Medication and Counseling for Controlled Drinking
Problem drinking gay and bisexual men who try to quit drinking are at risk for relapse to heavy or problematic drinking because their social lives and social outlets are often strongly associated with alcohol.
- Trial name
- ProjectSMART (NCT01115894)
- Testing
- Naltrexone, Modified Behavioral Self-Control Psychotherapy, Brief Behavioral Compliance Enhancement Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Alcohol Abuse
PARTNER Recruitment and Brief Intervention Pilot Study
Purpose of the study: This is a pilot randomized controlled trial to identify methods of involving underage youth in interventions to reduce alcohol use through the primary health care system.
- Trial name
- PARTNER (NCT00735956)
- Testing
- Counseling
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Duke University
Heavy Drinking
Exploring the Effects of Brief Mindfulness Training With Vagal Nerve Stimulation on Alcohol Cue Reactivity Among Young Adult Heavy Drinkers
The present study will assess the acceptability and feasibility of a brief intervention designed to help young heavy drinkers reduce their alcohol consumption.
- Trial name
- NCT07516873
- Testing
- Active RAVANS, Brief Mindfulness-Based Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cambridge Health Alliance
Arthritis Knee
The Effect of Stress on the Residual Gastric Volume
In our institution, many patients undergo staged bilateral total knee arthroplasty at weekly intervals, and most of the patients are older adults with degenerative arthritis.
- Trial name
- NCT05406245
- Testing
- Carbohydrate drinking
- Where
- South Korea
- Volunteers
- 53 people
- Sponsor
- Seoul National University Bundang Hospital
Alcohol Consumption, Alcohol Use Disorder
Effectiveness of an Intervention in Patients With Excessive Alcohol Consumption
Main objective: to verify the effectiveness of a brief intervention, based on the motivational interview (MI), in patients with excessive alcohol consumption assisted in Primary Care (PC).
- Trial name
- ALCO-AP20 (NCT04811729)
- Testing
- Motivational interview, Medical advice
- Where
- Spain
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Alcohol Use, Unspecified
Risk Factors for Stress-induced Alcohol Misuse: Genetic Predictors and Mediation by Personality Type
To examine whether variation in 'risk-taking' personality and linked genetic variants predicts susceptibility to, and resilience against, stress-induced alcohol misuse.
- Trial name
- RISK (NCT04533802)
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Alcohol Drinking, Violence
SafERteens M-Coach
This study will use a SMART (Sequential, Multiple Assignment Randomized Trial) design to optimize adaptive interventions (AIs) for adolescents reporting alcohol misuse and violent behaviors.
- Trial name
- NCT03344666
- Testing
- Step 1 Treatment BI+HC, Step 1 Treatment BI+TM, Step 2 Treatment Responders
- Where
- 4 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Michigan