Clinical trials: Driving
Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil
Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans
Alcohol is abused commonly, but there is no remedy for alcohol intoxication. This project is looking at the substance iomazenil and its effect on alcohol intoxication and alcohol's effects on driving using a driving simulator.
- Conditions
- Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil, Placebo Ethanol and Active Iomazenil, Placebo Ethanol and Placebo Iomazenil
- Trial name
- NCT01590277
- Testing
- Active Ethanol, Active Iomazenil
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Driving While Intoxicated
WayToServePlus: Improving Responsible Alcohol Service Ph I
Responsible beverage service (RBS) training for alcohol servers is a promising intervention for reducing driving while intoxicated (DWI) by alcohol.
- Trial name
- NCT05146024
- Testing
- Way To Serve Plus: Improving Responsible Alcohol Service
- Where
- 2 sites in United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Gout
Assessing the Role of the NLRP3 Inflammasome in Intercritical Gout
Gout is an autoinflammatory disease characterized by flares of painful joint inflammation. This inflammation occurs in response to uric acid that crystallizes.
- Trial name
- NCT04125459
- Testing
- Joint Biopsy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Attune Health Research, Inc.
Surgery
Esophageal Balloon Measurements to Better Characterize Thoraco-abdominal Interrelationship Mechanics.
Esophageal pressure measurements in surgical patients requiring mechanical ventilation during abdominal laparoscopic or robotic surgeries requiring intra-abdominal insufflation.
- Trial name
- NCT03624491
- Testing
- Esophageal pressure measurement guided ventilation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Trauma Prevention
Effectiveness of Distracted Driving Campaign
The study will measure the effectiveness of a distracted driving campaign in the emergency department in teenagers, 15 to 18 years old, to determine if it changes their attitudes towards texting while driving.
- Trial name
- NCT02437149
- Testing
- Video, Power Point, Brochure
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Injury
Preventing Motor Vehicle Crashes Among Young Drivers: Evaluation of the Checkpoints Program Presented by the American Automobile Association
Background: Automobile crash risks are highest right after licensure and decline rapidly for about 6 months and then gradually for years, regardless of the amount of supervised practice driving or age at licensure.
- Trial name
- NCT00920049
- Testing
- Persuasion
- Where
- United States
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Mental Health, Geriatrics
Impact of Cholinesterase Inhibitors on Driving Ability in Healthy Older Adults
The goal of the study is to assess the role of cholinesterase inhibitors in affecting the driving ability of cognitively intact seniors using driving simulators.
- Trial name
- NCT00482001
- Testing
- donepezil
- Where
- 2 sites in Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Alcoholism
Effects of Alcohol on Simulated Driving
Previous studies have shown that alcohol significantly impairs driving performance. Acute alcohol administration also has a detrimental effect on secondary task performance during dual-tasks.
- Trial name
- NCT00477984
- Testing
- alcohol
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
Driving Under the Influence, Cannabis-impaired Driving
In-Vehicle Real-Time Cannabis Influenced Driving Detection
The goal of this clinical trial is to evaluate whether in-vehicle sensor data can be used to detect cannabis-impaired driving in healthy adult recreational cannabis users.
- Trial name
- REVELIO (NCT07401628)
- Testing
- Cannabis (THC)
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Bern
Skin Diseases, Photoaging
Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida.
- Conditions
- Skin Diseases, Photoaging, Skin Hydration
- Trial name
- DCHA-FL-25-65 (NCT07764809)
- Testing
- BT-Analyze bioimpedance skin hydration measurement
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IAS Skin Care
Automobile Driving
Development of a Valid Test Battery for Assessing Driving Ability When Influenced by Drugs.
The purpose of the validation study is to develop a valid test battery for assessing driving ability in a driving simulator when influenced by drugs.
- Trial name
- VALIDAD (NCT00967421)
- Testing
- ethanol
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Drunk Driving, Alcohol Drinking
Design and Evaluation of an In-Vehicle Real-Time Drunk Driving Detection System
To analyze driving behavior of individuals under the influence of alcohol while driving in a real car. Based on the in-vehicle variables, the investigators aim at establishing algorithms capable of discriminating sober and drunk…
- Conditions
- Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT05796609)
- Testing
- Driving under the influence of alcohol
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Homonymous Hemianopia
Assessment of Homonymous Visual Loss and Its Impact on Visual Exploration, Activities of Daily Living (ADL) and Quality of Life (QoL)
The purpose of this explorative study, targeting subjects with homonymous visual field loss, is threefold: (i) to identify the perimetric / psychophysical method, that is most closely correlated with an individually assessed…
- Trial name
- Hemi-Drive (NCT01372332)
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Cannabis
Detection of Cannabis Impairment With ISBRG's SpotLight-THC
Subjects will participate in a 2-visit study protocol in which they will be administered cannabis of pre-determined concentrations and asked to complete a simulated drive in a driving simulator.
- Trial name
- NCT05276232
- Testing
- Cannabis(THC) inhaled
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- ISBRG Corp
Distracted Driving, Driving Impaired
Reducing Cell Phone Use While Driving Among High Risk UBI Auto Policy Holders
Insurance User Based Insurance (UBI) users will be invited to participate in a randomized control trial where they will be randomized into 1 of 4 arms: (Arm 1) standard UBI, (Arm 2) Standard UBI + Free phone mounts (Arm 3)…
- Trial name
- NCT04587609
- Testing
- Free Phone Mounts, Commitment Contract, Personalized Habit Tips
- Where
- United States
- Volunteers
- 1,668 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cannabis, Driving Under the Influence
Cannabis Edibles and Simulated Driving
The goal of this human laboratory experiment is to determine the acute and residual effects of a range of doses of orally administered cannabis edibles on driving simulator performance in people who use cannabis recreationally.
- Trial name
- NCT06595576
- Testing
- Cannabis - Low Dose (2 mg), Cannabis - Medium Dose (10 mg), Cannabis - High Dose (20 mg)
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Cognitive Measures, Driving Simulator Performance
Phenytoin and Driving Safety: A Randomized, Controlled Cross-Over Study
Automobile driving is a crucial aspect of everyday life, yet vehicular crashes represent a serious public health problem. Patients with epilepsy are at elevated risk for automobile crashes, causing great personal suffering and…
- Trial name
- NCT00581893
- Testing
- Phenytoin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Drunk Driving
Leveraging Transdermal Alcohol Monitoring to Reduce Drinking Among DWI Defendants
The current study will evaluate the efficacy of contingency management (i.e., reinforcement for avoiding heavy drinking) among adults arrested for drunk driving and who are at risk for ongoing heavy drinking.
- Trial name
- NCT03638596
- Testing
- Contingency Management, Control
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Anesthesia, Psychomotor Status
Driving Skills Recovery Following Procedural Sedation for Gastrointestinal Endoscopy
This is a prospective cohort study that will analyze psychomotoric recovery using a commercially available driving simulator following sedation for endoscopic procedures in subjects undergoing elective outpatient endoscopic…
- Trial name
- NCT04350424
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Healthy
Fermented Papaya and Driving Simulator Older Adult Study
Yes, this additional detail will refine the original template content to emphasize the study's specific aims and hypotheses. Here's an updated version: The goal of this clinical trial is to assess if Fermented Papaya Preparation…
- Trial name
- FPP (NCT06672874)
- Testing
- Fermented Papaya Preparation (FPP)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida