Clinical trials: Driving Behaviors
Behaviors, Driving
Vehicle Automation Impact on Drivers
In the context of ever-increasing automation in surface vehicles, automation impact on drivers will be investigated through three complementary research axes undertaken under simulated driving: Axe 1 (Cognitive ergonomics), how…
- Conditions
- Behaviors, Driving, Automation, Neuroimaging
- Trial name
- AUTODRIVE (NCT03893006)
- Testing
- Level of vehicle automation
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Attention Deficit Disorder With Hyperactivity
Sleepiness and Driving Performances in Adults With Attention-Deficit/ Hyperactivity Disorder (ADHD)
The Attention Deficit/ Hyperactivity Disorder (ADHD) is a developmental disorder which affects 3 to 5 % of school age children. This disorder persists in the adulthood for 60 % of subjects.
- Trial name
- SOMTDA/H (NCT01160874)
- Testing
- Polysomnography, Maintenance Wakefulness Test, Neuropsychological evaluation
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Driving Impaired
Validation of Alcohol Level Identification Using DRIVESC
This pilot study will evaluate the feasibility and acceptability of using a commercially available DRIVESC fitness-to-drive measurement tool to detect alcohol-induced impairment in healthy adult participants.
- Trial name
- NCT07282405
- Testing
- DRIVESC, Alcohol
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Intoxication by Drug
Concentrations of Nitrous Oxide in Blood, Exhaled Air and Urine After Various Types of Exposure.
The study examines the concentrations of nitrous oxide that are achieved in blood, exhaled air, and urine after three different exposures to nitrous oxide: inhalation of three or four cartridges of nitrous oxide released in a car…
- Trial name
- NCT07690358
- Testing
- Nitrous Oxide 99 %, Nitrous Oxide + Oxygen Gas
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Type 1 Diabetes, Hypoglycemia
Identifying Driving Risk Factors in Type 1 Diabetes and Their Reduction Via Internet Program (DiabetesDriving.Com)
This study will recruit drivers with Type 1 diabetes from across the U.S. and assign them to four groups based on their presumed risk level- routine care low risk, routine care high risk, or to one of two Internet interventions…
- Trial name
- NCT01563887
- Testing
- DD.com, DD.com + MI
- Where
- United States
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Motor Vehicle Crash Injuries
Teenage Passenger Influences on Driving Performance of Teenage Drivers
This study, conducted at the University of Massachusetts at Amherst, will examine how male teenage driving performance varies in the presence or absence of male teenage passengers.
- Trial name
- NCT00716378
- Testing
- Teen Passenger Presence
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
ADHD
Amphetamine Extended Release Tablets and Driving Performance in Subjects With Attention Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to assess the effect on driving performance of a single dose of amphetamine extended-release tablets (20 mg/tablet) compared with placebo at 45 minutes and 10 hours post-dose in young adults with ADHD.
- Trial name
- NCT04027361
- Testing
- Amphetamine Extended Release (ER) Tablet 20 mg
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Tris Pharma, Inc.
Bipolar Disorder I or II, Healthy (Controls)
Decoding Emotional Dynamics in Bipolar Disorder
The goal of this neuroimaging study is to investigate how emotional states fluctuate in people with bipolar disorder (BD) compared to healthy controls, and to understand the neural mechanisms driving mood instability.
- Trial name
- NCT07221864
- Testing
- Think and Regulate Affective State Task
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Driving Behavior, Driving Under the Influence
Validation of the Drug Impaired Driving Scenario (DIDS) on the CRCDS-miniSim
Subjects will participate in a 4-visit study protocol at the National Advanced Driving Simulator, part of the University of Iowa, in which they will be asked to complete assorted questionnaires, computerized cognitive tasks, and…
- Trial name
- PDID (NCT04970342)
- Testing
- 0.75 mg Alprazolam Capsule, Cannabis (6.18% THC / <0.025% CBD), Cannabis (0%/ THC / 0% CBD)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Timothy L. Brown
Cannabis Smoking, Driving Impaired
Cannabis Consumption and Driving Impairment Assessment on a Closed Course
In a true experiment, roughly 300 volunteer participants will smoke active cannabis, a corresponding placebo, or no substance at all (control).
- Trial name
- NCT06059677
- Testing
- Active smoked cannabis
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bayliss J. Camp, PhD
ADHD - Attention Deficit Disorder With Hyperactivity
ADRIS Driving Simulator for Adolescents With Attention Deficit and Hyperactivity Disorder
This study aims to evaluate a new driving simulator, called ADRIS 2.1, developed for adolescents aged 13-18 years with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- ADRIS-ADHD (NCT07478458)
- Testing
- ADRIS-ADHD
- Where
- 2 sites in Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istituto Giannina Gaslini
Transpulmonary Pressure, Pressure.Rate Product
Measuring Lung Pressures in Critically Ill Children Who Are on Mechanical Ventilation
Typically doctors adjust the settings on the ventilator to ensure that children receive enough help to decrease the work they perform to breathe, receive enough oxygen through the machine to pass into the blood and to the organs…
- Conditions
- Transpulmonary Pressure, Pressure.Rate Product, Guide to Mechanical Ventilator Management, Extubation Readiness
- Trial name
- NCT02354365
- Testing
- Transpulmonary Pressure measurement
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Children's Hospital Los Angeles
Sleepiness, Daytime, Fatigue
Lifestyle Medicine Strategies for Combating Sleepiness and Fatigue in Professional Drivers
Sleep has a number of health benefits, including memory and learning, vitality and energy as well as high quality of life levels.
- Conditions
- Sleepiness, Daytime, Fatigue, Sleep Disorders, Circadian Rhythm
- Trial name
- HighWay2Health (NCT05096130)
- Testing
- Lifestyle Medicine Strategies
- Where
- Greece
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Thessaly
Blood Alcohol Concentration, Drunk Driving
Community-based Partnership's Efficacy in Decreasing Injury Rates At Night in Dallas, TX
According to the Centers for Disease Control and Prevention (CDC), "88,000 people die every year due to alcohol-related issues including homicide, sexual assault, intimate partner violence, and suicide".
- Trial name
- NCT06695416
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Methodist Health System
Driving Under the Influence
Combined and Separate Effects of Cannabis and Tobacco: Psychomotor, Subjective and Physiological Outcomes
Co-administration of cannabis and tobacco is a common practice, but there is little experimental evidence aimed at understanding the reasons for this prevalence.
- Trial name
- CASE-CT (NCT05526196)
- Testing
- Cannabis, Tobacco, Cannabis tobacco
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Risk Reduction Behavior, Injuries
Driver Education Research Study
This study will test the effectiveness of different types of driver training interventions for reducing young new driver crash risk early after licensure.
- Conditions
- Risk Reduction Behavior, Injuries, Accident, Traffic, Development, Adolescent
- Trial name
- DRIVER (NCT06413927)
- Testing
- Online Vehicle and Driver Safety Education, Online Driver Skills Training, Behind-the-Wheel Driver Training
- Where
- United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Attention Deficit Hyperactivity Disorder (ADHD)
Improving ADHD Teen Driving - Virtual Reality
Teens with Attention-Deficit/Hyperactivity Disorder (ADHD) have high rates of negative driving outcomes, including motor vehicle crashes, which may be caused by visual inattention (i.e., looking away from the roadway to perform…
- Trial name
- NCT06960980
- Testing
- FOCAL+, VR-FOCAL+
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Distracted Driving, Impaired Driving
Increasing Seat Belt Wearing and Decreasing Handheld Phone Use While Driving
The study team is proposing to conduct a randomized controlled trial to determine the effectiveness of behavioral and financial incentives on phone use while driving and seat belt adherence.
- Conditions
- Distracted Driving, Impaired Driving, Driving Behaviors
- Trial name
- NCT05469477
- Testing
- Persuasive education, WOOP (aka, mental contrasting with implementation intentions., Wish, Outcome, Obstacle, Plan), Customized Habit Tips
- Where
- United States
- Volunteers
- 1,139 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Depression, Drive
Depression and Driving
This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years).
- Trial name
- D&D (NCT05446805)
- Testing
- F 18 AV-1451 (Flortaucipir), [11C]-Pittsburgh Compound B ([11C]PiB)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Washington University School of Medicine
Flying Phobia
Use of Virtual Reality in the Treatment of Flying Phobia
The project aims to explore the potential of Virtual Reality Exposure Therapy (VRET) for the treatment of the fear of driving, the fear of flying and the fear of public speaking.
- Trial name
- NCT01442805
- Testing
- Virtual Reality Exposure Therapy, Exposure Therapy through Imagination
- Where
- Luxembourg
- Volunteers
- 36 people
- Sponsor
- Luxembourg Institute of Health