Clinical trials: Driving Impaired
Alcohol Drinking, Alcohol Intoxication
Smartphone-paired Breathalyzers and Loss- and Gain-framed Texts for Reducing Drinking and Driving
This project aims to demonstrate the feasibility of a scalable behavioral intervention using smartphone-paired breathalyzers and text message aimed at reducing drinking and driving among individuals who report heavy drinking.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Impairment, Drive
- Trial name
- BESAFE (NCT03335735)
- Testing
- Loss-framed text message, Gain-Framed text message
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cannabis
Detection of Cannabis Impairment With ISBRG's SpotLight-THC
Subjects will participate in a 2-visit study protocol in which they will be administered cannabis of pre-determined concentrations and asked to complete a simulated drive in a driving simulator.
- Trial name
- NCT05276232
- Testing
- Cannabis(THC) inhaled
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- ISBRG Corp
Marijuana Impairment, Alcohol Impairment
Examine the Feasibility of a Standardized Field Test for Marijuana and Alcohol Impairment: Laboratory Evaluations
Alcohol and Cannabis (CNB) are two of the most widely used intoxicants. The effects of driving while intoxicated on alcohol are well documented, resulting in numerous drunken driving laws and regulations.
- Trial name
- Alc-NHTSA (NCT04856566)
- Testing
- Low Marijuana, Hash, THC, or Grass, High Marijuana, Hash, THC, or Grass, 0.05 BAC Alcohol
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Yale University
Cannabis Use, Impaired Driving
Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance
The purpose of this research is to determine the extent to which oculomotor function accurately detects THC-impairment, if cannabis use experience impacts this detection threshold, and to examine how the oculomotor index…
- Conditions
- Cannabis Use, Impaired Driving, Cognitive Impairment
- Trial name
- NCT06351540
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Psychomotor Impairment
Cannabis Effects on Driving-related Skills of Young Drivers
Motor vehicle collisions are the leading cause of death for young people. The investigators have recently found that driving after using cannabis is more common among young Canadian drivers than driving after drinking.
- Trial name
- NCT01592409
- Testing
- delta-9-tetrahydrocannabinol
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Marijuana Impairment
Examine the Feasibility of a Standardized Field Test for Marijuana Impairment: Laboratory Evaluations
Marijuana is one of the most widely used substances. This study will characterize the persistence of cannabis' (CNB's) acute effects on cognitive test performance and simulated driving over a several hour time period.
- Trial name
- NCT03191084
- Testing
- Low Dose THC Marijuana, High Dose THC Marijuana
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Yale University
Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil
Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans
Alcohol is abused commonly, but there is no remedy for alcohol intoxication. This project is looking at the substance iomazenil and its effect on alcohol intoxication and alcohol's effects on driving using a driving simulator.
- Conditions
- Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil, Placebo Ethanol and Active Iomazenil, Placebo Ethanol and Placebo Iomazenil
- Trial name
- NCT01590277
- Testing
- Active Ethanol, Active Iomazenil
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Shift-Work Sleep Disorder, Insomnia
Fire Fighter Fatigue Management Program: Operation Healthy Sleep
Firefighters work some of the most demanding schedules known under highly stressful and demanding conditions. The need to work frequent extended shifts and long work weeks leads to acute and chronic partial sleep deprivation as…
- Conditions
- Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT01988129
- Testing
- Sleep disorders education and screening
- Where
- United States
- Volunteers
- 1,189 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Impairment, Cognitive, Impairment of Attention
High Confusion: Cannabis & Driving
This study is being done to assess the feasibility of administrating Δ9-THC and Δ8-THC isolates and simultaneously adopting several data harmonization measures to generate uniquely translatable data.
- Conditions
- Impairment, Cognitive, Impairment of Attention, Impairment, Psychomotor
- Trial name
- NCT06236815
- Testing
- Delta-9-THC, Delta-8-THC
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Driving Performance, Cognitive Impairment
The Effects of Cannabidiol on the Driving Ability of Healthy Adults
A randomized, parallel-group, double-blind, exploratory two-arm trial to assess the effects of CBD on driving ability along with changes in psychological status (i.e. mood, drowsiness, sedation) and cognitive function.
- Conditions
- Driving Performance, Cognitive Impairment, Sedation Complication, Mood
- Trial name
- NCT04590495
- Testing
- 300 mg Cannabidiol (CBD) oil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Driving, Intoxication
Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving
The proposed study will validate and determine sensitivity of our new driving simulator, created to evaluate driving ability in a related study to show similar driving performance between patients on chronic opioid treatment and…
- Conditions
- Driving, Intoxication, Impairment, Alcohol Impaired Driving
- Trial name
- ALCDrive (NCT00559819)
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Distracted Driving, Impaired Driving
Increasing Seat Belt Wearing and Decreasing Handheld Phone Use While Driving
The study team is proposing to conduct a randomized controlled trial to determine the effectiveness of behavioral and financial incentives on phone use while driving and seat belt adherence.
- Conditions
- Distracted Driving, Impaired Driving, Driving Behaviors
- Trial name
- NCT05469477
- Testing
- Persuasive education, WOOP (aka, mental contrasting with implementation intentions., Wish, Outcome, Obstacle, Plan), Customized Habit Tips
- Where
- United States
- Volunteers
- 1,139 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cannabis Smoking, Driving Impaired
Cannabis Consumption and Driving Impairment Assessment on a Closed Course
In a true experiment, roughly 300 volunteer participants will smoke active cannabis, a corresponding placebo, or no substance at all (control).
- Trial name
- NCT06059677
- Testing
- Active smoked cannabis
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bayliss J. Camp, PhD
Psychomotor Impairment
Alcohol Effects on Driving-related Skills of Young Drivers
Given the known driving behavior of Driving Under the Influence of Alcohol and some of its parallel to driving under the influence of cannabis, this supplemental study aims to validate the sensitivity of the primary and secondary…
- Trial name
- NCT02710578
- Testing
- Alcohol
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Marijuana Impairment
Neuroscience of Marijuana Impaired Driving
Marijuana is one of the most widely used substances. However, marijuana intoxication is not fully understood in relation to driving.
- Trial name
- MJDriving (NCT02757313)
- Testing
- Low dose THC marijuana, High dose THC marijuana
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yale University