Clinical trials: Drug Application
Dentinal Hypersensitivity
Research on Oral Tolerability and Product Application/Response of Two Oxalate Products for Dental Patients With Risk of Dentinal Hypersensitivity
This study will assess the oral tolerability and immediate post-treatment safety of topical application for two marketed oxalate products as initial care in dental patients to treat or prevent tooth sensitivity pain that may be…
- Trial name
- NCT02613117
- Testing
- Potassium Oxalate Gel, Potassium Oxalate Liquid, Stannous fluoride paste
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Asthma
Effects of the Kata® Inhalations-App on Inhaler Handling Errors, Adherence, and Asthma Control in Patients With Asthma.
The Kata® App is a digital therapy assistant for patients with asthma who need to inhale their therapy. Kata features inhalation trainers that shows patients in a simple and understandable way how to improve their inhalation…
- Trial name
- NCT06178341
- Testing
- Kata Inhalations-App
- Where
- 13 sites in Germany
- Volunteers
- 146 people
- Sponsor
- VisionHealth GmbH
Pelvic Floor Awareness
The Effect of Training Based on the Transtheoretical Model on Pelvic Floor Muscle Strength
The study was designed to evaluate the effect of training based on the transtheoretical model on pelvic floor muscle strength in women.
- Trial name
- NCT07443423
- Testing
- TRAINING BASED ON THE TRANSTEOROTİK MODEL, Not providing training
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Aynur Erçek Karci
Electrode Site Reaction, Therapy
Functional Electrostimulation on the Upper Lip in Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune disease where immune cells attack the body, triggering an inflammatory response. A study comparing multifield FES and conventional FES on upper extremity motor skills and functional…
- Conditions
- Electrode Site Reaction, Therapy, Directly Observed Therapy
- Trial name
- EM/2024 (NCT06638775)
- Testing
- Fesia Grasp, GLOBUS ELITE
- Volunteers
- 30 people
- Sponsor
- Universidad de Burgos
Cardiovascular Diseases, Cardiac Rehabilitation
SMART to Optimize an Intervention to Maintain Health Improvements After Cardiac Rehabilitation
The study is sponsored by the National Heart, Lung, and Blood Institute, which is part of the National Institutes of Health. The study expects to enroll 400 subjects.
- Trial name
- EMPOWER ME (NCT06886789)
- Testing
- Text Messaging, Fully Automated Online Program, Low-Intensity Cardiac Rehabilitation Maintenance Program
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- The Miriam Hospital
Warts
An up to Twelve Week Safety and Efficacy Study With a Topical Gel to Treat Common Warts in Pediatric Subjects
The primary purpose of this study is to evaluate the effectiveness in pediatric subjects of three different strengths of resiquimod gel applied to common wart(s) three times a week for up to twelve weeks.
- Trial name
- NCT00116662
- Testing
- Resiquimod
- Where
- 10 sites in United States
- Volunteers
- 84 people
- Sponsor
- Graceway Pharmaceuticals, LLC
Schizophrenia, Schizo Affective Disorder
Feasibility and Acceptability of Mobile Mental Health App for SZ and SZA
A new mental health application will be developed for persons with schizophrenia and schizoaffective disorder. The aim is to look at whether it is feasible to use a mobile health application for improving medication adherence in…
- Trial name
- NCT06474325
- Testing
- Intervention via mobile application
- Where
- India
- Volunteers
- 44 people
- Sponsor
- University of Pittsburgh
Bronchial Asthma, Adherence, Medication
Efficacy of a Phone Application on Treatment Adherence in Asthmatic Patients in Upper Egypt
asthma adherence is mandatory for disease control
- Trial name
- NCT06233123
- Testing
- the Medisafe android application (https://www.medisafe.com).
- Volunteers
- 180 people
- Sponsor
- Assiut University
HIV Infections, Gonorrhea
Cellulose Sulfate (CS) Gel and HIV in Nigeria
This is a Phase 3, multi-center, randomized, placebo-controlled trial to determine the effectiveness and safety of the 6% cellulose sulfate (CS) vaginal gel for the prevention of HIV infection.
- Conditions
- HIV Infections, Gonorrhea, Chlamydia Infections
- Trial name
- NCT00120770
- Testing
- Cellulose Sulfate Vaginal Gel (Microbicide)
- Where
- 2 sites in Nigeria
- Volunteers
- 2,160 people, healthy volunteers welcome
- Sponsor
- FHI 360
Myasthenia Gravis
Application of Artificial Intelligence in Precision Medicine and Healthcare
This study aims to propose an intelligent health robot that utilizes remote intelligent robots to assist patients with disease-related issues, enabling them to address their problems promptly.
- Trial name
- NCT06879210
- Testing
- Mobile device.(phone)
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Yi Ting Yeh
Pediatric Nursing, Drugs, Investigational
Pediatric Drug Application
The aim of this study was to evaluate the effectiveness of jigsaw, metaverse and classical learning models in developing self-efficacy in medication administration of students taking pediatric nursing courses.
- Trial name
- NCT06836674
- Testing
- Jigsaw, Metaverse, Classical Education
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Fissure Sealant, Deproteinization
Evaluation of the Survival of Fissure Sealants Applied With Different Pretreatment Methods on Permanent First Molars: A One-Year Follow-Up
Objective: This study aims to evaluate the effect of two different pretreatment protocols-enamel deproteinization and bonding agent application-on the one-year survival of fissure sealants applied to permanent first molars in…
- Conditions
- Fissure Sealant, Deproteinization, Bonding Agent, Molar Teeth
- Trial name
- NCT07136051
- Testing
- Ethcing, Deproteinization, Bonding
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Handan Vural
Injection Site Reaction, Injection Site Bruising
Effectiveness of Mechano-Analgesia and Cold Application on Ecchymosis, Pain and Satisfaction at Subcutaneous Heparin Injection
Fifty-five patients received three subcutaneous heparin injections (165 injections) by the same investigator using additional techniques such as mechano-analgesia and cold application, and without any additional techniques.
- Trial name
- NCT03645369
- Testing
- ShotBlocker, Ice pack
- Volunteers
- 165 people
- Sponsor
- Istanbul Saglik Bilimleri University
Point of Care Ultrasound (POCUS), Ultrasound Exam in Emergency/Medical Care
Evaluation of an Online Application for Point of Care Ultrasound Training in General Internal Medicine Residents
This study compares Point of Care Ultrasound (POCUS) training in two hospitals, one that uses an online application for supervision and one that does not use the application.
- Conditions
- Point of Care Ultrasound (POCUS), Ultrasound Exam in Emergency/Medical Care, Ultrasound Evaluation
- Trial name
- NCT07372053
- Where
- 2 sites in Switzerland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Baden
Mental Disorder
Early Identification of Mental Disorders: Application of a Multi-modal & Domains System
This study aims to build a multi-modal collection template and establish a multi-modal database of seven mental disorders including depressive disorders, bipolar disorders, schizophrenia, obsessive-compulsive disorder, anxiety…
- Trial name
- NCT05939154
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obesity and Type 2 Diabetes
Stem Cell Isolation From Femoral Heads Post Total Hip Arthroplasty
Femoral heads will be collected at University Hospital (London, ON, Canada) from individuals with type-2 diabetes, obesity, and no T2D/no obesity controls.
- Trial name
- NCT06775600
- Testing
- Hip Replacement
- Volunteers
- 30 people
- Sponsor
- David Hess
Substance Use Disorders
Repetitive Transcranial Magnetic Stimulation in Drugs Addiction
This study also aims to develop and apply a standard repetitive transcranial magnetic stimulation (rTMS) protocol on drug users.
- Trial name
- NCT06244329
- Testing
- Transcranial magnetic stimulation
- Where
- Hong Kong
- Volunteers
- 48 people
- Sponsor
- The Hong Kong Polytechnic University
Mild Cognitive Impairment, Alzheimer's Disease
A Validation Study of the Novel Application of Telehealth in Clinical Drug Development in Subjects With Mild Cognitive Deficits
REINVENT is a non-interventional, multi-center, research network-based cross-over study evaluating the potential utility of a telehealth platform in improving the efficiency of clinical trials.
- Trial name
- REINVENT (NCT02778438)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Quintiles, Inc.
Periodontal Pocket
The Proposed Study Aims to Investigate the Impact of Adjunctive Vitamin D Gel Application on Gingival Crevicular Fluid Levels of Alkaline Phosphatase and Interleukin-8 in Periodontitis Patients Undergoing Phase 1 Periodontal Therapy. By Elucidating the Molecular Mechanisms Underlying the Therapeutic
The proposed study aims to investigate the impact of adjunctive vitamin D gel application on gingival crevicular fluid levels of alkaline phosphatase and interleukin-8 in periodontitis patients undergoing phase 1 periodontal…
- Trial name
- NCT06669026
- Testing
- vitamin D loaded Poly lactic-co-glycolic acid nanoparticles gel, vitamin D3 gel (regular non-nanoparticle form), only mechanical debridement
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Kidney Transplant, Drug-Related Side Effects and Adverse Reactions (MeSH Term)
The Effect of the 5th Sign Intervention on Medication Adherence in Kidney Transplant Recipients
The goal of this randomized controlled trial is to evaluate the effectiveness of the "5th Sign" intervention program-a multi-component strategy based on the Socio-Ecological Model that incorporates goal setting, action planning…
- Conditions
- Kidney Transplant, Drug-Related Side Effects and Adverse Reactions (MeSH Term), Medication Adherence, Mobile Applications
- Trial name
- NCT07851142
- Testing
- 5th Sign Intervention Program
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dokuz Eylul University