Clinical trials: Drug Application
Psoriasis
Evaluating the Efficacy and Tolerability of Application of Metaderm Product for the Treatment of Psoriasis
Psoriasis vulgaris is a common inflammatory condition of the skin that results in well-demarcated, scaly, erythematous, itchy plaques.
- Trial name
- NCT03597620
- Testing
- Metaderm
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Alabama at Birmingham
Stable Angina Pectoris
Acupoint Application in Patients With Stable Angina Pectoris (AASAP)
Hypothesis: acupoint application is effective for managing chronic stable angina pectoris. Aim: to evaluate the efficacy and safety of acupoint application on the specific acupoints for chronic stable angina pectoris.
- Trial name
- AASAP (NCT02029118)
- Testing
- Herbal plaster ( styrax, borneol, frankincense, santalum,trichosanthes kirilowii Maxim, allium macrostemon Bunge, leech), acupoint, Aspirin: 100mg qd; Metoprolol：25mg bid; Ramipril:5mg qd; Atorvastatin:20mg qn.
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Advanced Cancer, Solid Tumor, Adult
Molecular Services and EMR-Lab Integration Application (ELIA) for Reducing Healthcare Disparities in Cancer Patients
The goal of this observational study is to measure and try to reduce leakage in precision medicine care in the community cancer clinic.
- Conditions
- Advanced Cancer, Solid Tumor, Adult, Myeloid Malignancy
- Trial name
- NCT06090513
- Testing
- Comprehensive Genomic Profile testing; ELIA software; Molecular Genetic Pathologist consultation, limited genetic testing or no testing
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Bien-Willner Physicians Group PA
Mechanical Ventilation, Acute Respiratory Distress Syndrome
Ventilation's Parameters Applied in Emergency Medicine. A Prospective Observational Study
To prospectively assess the mechanical ventilation management when its provided by Emergency Physicians in French Hospital, and to assess complications and outcome of these patients.
- Conditions
- Mechanical Ventilation, Acute Respiratory Distress Syndrome, Protective Ventilation, Survival
- Trial name
- PARAVENT (NCT03351920)
- Testing
- mechanical ventilation
- Where
- 7 sites in France
- Volunteers
- 229 people
- Sponsor
- Poitiers University Hospital
Intraoperative Bleeding
Adjunctive Application of BioFoam Surgical Matrix in Liver Surgery
This is a prospective, multicenter, randomized, controlled investigation. Subjects in which bleeding from the exposed parenchymal surface is observed intraoperatively following the ligature of vessels visible with the unaided eye…
- Trial name
- BARRIER (NCT01458561)
- Testing
- BioFoam Surgical Matrix, Gelfoam Plus
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- CryoLife, Inc.
Hypertension, Diabetes Mellitus, Type 2
Use and Acceptability of an AI-Assisted Health Application for Individuals Living With a Chronic Condition
The SOFIA study evaluates a web-based health application for people living with one or more chronic conditions. The study aims to find out whether the SOFIA application is useful, easy to use, and used over time by participants.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Obesity
- Trial name
- SOFIA (NCT07916753)
- Testing
- SOFIA application
- Where
- Switzerland
- Volunteers
- 1,600 people
- Sponsor
- Fondation Net-Care.ch
Skin Flora Bacterial Reduction Post-product Application
In-vivo Efficacy Study of Patient Preoperative Preps
The purpose of this study is to evaluate the antimicrobial efficacy of the 3M CHG/IPA Prep on skin flora of the abdominal and inguinal regions of human subjects.
- Trial name
- NCT01968356
- Testing
- 3M CHG/IPA Prep Colorless, 3M CHG/IPA Prep Tint, ChloraPrep
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Androgenetic Alopecia
Efficacy and Safety of CosmeRNA-ARI Anti Hair Loss Tonic in Adults With Androgenetic Alopecia
This study evaluated the efficacy and safety of two concentrations of CosmeRNA-ARI Anti Hair Loss Tonic in adults with androgenetic alopecia.
- Trial name
- NCT07898566
- Testing
- Low-Concentration CosmeRNA-ARI Anti Hair Loss Tonic, High-Concentration CosmeRNA-ARI Anti Hair Loss Tonic, Vehicle Control Tonic Without CosmeRNA-AR
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- BIONEER Corporation
Bioequivalence Study
Bio-equivalence Vasoconstriction Activity Study for Topically Applied Clocortolone Pivalate 0.1% Cream
To compare pharmacodynamic vasoconstriction response profile of Clocortolone Pivalate 0.1% Cream and Cloderm® (Clocortolone Pivalate) 0.1% Cream in normal skin of healthy male and female adults
- Trial name
- NCT04358770
- Testing
- Clocortolone Pivalate
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Perioperative Medication Errors, Perioperative Adverse Medication Events
RCT: The Effect of an Electronic Clinical Decision Support Application on Perioperative Medication Errors.
The purpose of this study is to assess the effect of a novel clinical decision support application on the rate of perioperative medication errors and preventable adverse medication events.
- Trial name
- NCT04342013
- Testing
- Electronic Clinical Decision Support Application
- Volunteers
- 300 people
- Sponsor
- Karen C. Nanji,M.D.,M.P.H.
Lower Gastrointestinal Neoplasms Benign, Pancreas Cancer
The Effects of Perioperative Painting Art Therapy (LOM® Solution Centered Art Therapy) in Surgical Patients
The investigators want to study whether the use of painting art therapy has an influence on the quality of life, the complication rate and the general outcome of major abdominal surgery.
- Conditions
- Lower Gastrointestinal Neoplasms Benign, Pancreas Cancer, Posttraumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT04524260
- Testing
- perioperative painting art therapy (LOM® solution centered art therapy), perioperative painting art therapy (LOM® solution centered art therapy) - control
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Satisfaction, Personal
Participant Satisfaction With the BUILD Mobile Application
This study explores user satisfaction with the BUILD mobile application.
- Trial name
- NCT05948670
- Testing
- DISC-MVP, DISC-CON
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Woebot Health
Pharmacokinetics of CBD Extract, Oral and Topical Administrations
Pharmacokinetic Evaluation of a Natural CBD Extract
The present cross-over study investigated whether cannabidiol (CBD) or its metabolites and delta-9-tetrahydrocannabinol (THC) can be detected in the systemic circulation following a single topical application of a natural hemp…
- Trial name
- NCT07359976
- Testing
- CBD extract
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obese Adults, BMI/Body Composition
Precision Lifestyle Medicine Program for IFHAS Participants
The goal of this clinical trial is to evaluate whether a precision lifestyle medicine intervention can improve cardiometabolic health in Emirati adults aged 25 to 50 years living in Abu Dhabi with obesity (BMI 30-35 kg/m²) who…
- Conditions
- Obese Adults, BMI/Body Composition, Cardiometabolic Risk, Cardiovascular Disease Risk
- Trial name
- NCT07742917
- Testing
- Precision Lifestyle Medicine Program, Standard IFHAS Care
- Where
- United Arab Emirates
- Volunteers
- 150 people
- Sponsor
- Institute for Healthier Living Abu Dhabi
Drug Abuse
An Explorative Pilot Study of a New Mobile Phone Application Measuring Eye Parameters of Eyes in Patients With SUD
This will be a pre-market, explorative, early feasibility, pilot, controlled clinical investigation designed to collect initial clinical data for Previct Drugs.
- Trial name
- NCT05737550
- Testing
- Previct Drugs
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Kontigo Care AB
Ischemic Heart Disease (IHD)
XTR003 PET Radiotracer for the Detection of Viable Myocardium
The study was designed to explore the clinical feasibility of XTR003, a PET myocardial fatty-acid tracer, for the detection of viable myocardium in patients with ischemic heart disease (IHD).
- Trial name
- NCT05885854
- Testing
- XTR003
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Sinotau Pharmaceutical Group
Burnout, Professional, Depression
Does a Phone-based Meditation Application Improve Mental Wellness in Emergency Medicine Personnel?
Emergency medicine is notorious for its high rate of burnout and mental health issues. The emergency department (ED) is a high paced work environment dealing with life and death issues.
- Conditions
- Burnout, Professional, Depression, Anxiety, Stress
- Trial name
- NCT03811990
- Testing
- Cleveland Clinic Stress Free Now Meditations For Healers
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Leptomeningeal Metastasis From Lung Cancer
Exploration of the Application of Methotrexate-loaded Drug Vesicles in Intrathecal Injection for Meningeal Metastasis of Lung Cancer
This is a phase I/II, single-arm, open-label, single-center clinical trial to evaluate the safety, tolerability, and preliminary efficacy of intrathecal injection of methotrexate-loaded autologous tumor cell-derived…
- Trial name
- NCT07559097
- Testing
- Methotrexate-loaded vesicles
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Henan Cancer Hospital
Expression of Integrin ανβ3 in Lung Cancer
Identification of Integrin ab Expression in Lung Cancer Patients
It has been reported that the expression rates of integrin αvβ3 and integrin αvβ5 in NSCLC are 89% and 100%, respectively. Among RGD (Arg-Gly-Asp) peptides, cRGDyK peptide (cRGD) known as integrin ανβ3 and ανβ5 antagonist has…
- Trial name
- NCT06167941
- Testing
- Lung cancer types
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- Korea University Guro Hospital
Pain
Treatment of the Symptomatic Sacral Perineurial Cysts
There are very few data and analysis in the literature regarding the symptomatic sacral perineurial cysts. Most studies are case reports or small retrospective sample, which rarely more than 20 cases.
- Trial name
- TSSPC (NCT02595190)
- Testing
- sacral canal cyst microscopic tamponade, gabapentin + tramadol, resting state functional magnetic resonance imaging (rfMRI)
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Southwest Hospital, China