Clinical trials: Drug Application
Lymphatic Filariasis Elimination by Mass Drug Administration, Monitoring and Evaluation of Mass Drug Administration for Lymphatic Filariasis
East New Britain Province Monitoring & Evaluation
While tremendous progress towards elimination of lymphatic filariasis (LF) has been made in the 20 years since the 1997 Fiftieth World Health Assembly, it is unlikely the goal of eliminating LF as a public health problem by 2020…
- Conditions
- Lymphatic Filariasis Elimination by Mass Drug Administration, Monitoring and Evaluation of Mass Drug Administration for Lymphatic Filariasis, Acceptability of Mass Drug Administration for Lymphatic Filariasis
- Trial name
- ENBP M&E (NCT04124250)
- Testing
- Observational
- Where
- Papua New Guinea
- Volunteers
- 12,930 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Acne
Pilot Study to Evaluate Tea Tree Oil Gel for Facial Acne
Mild to moderate facial acne is an extremely common disease of teenagers and young adults. This pilot study will investigate whether treatment with a gel containing tea tree oil reduces numbers of acne lesions and improves acne…
- Trial name
- NCT01657110
- Testing
- Tea tree oil
- Where
- 2 sites in Australia
- Volunteers
- 18 people
- Sponsor
- The University of Western Australia
Cigarette Smoking
Mobile App Based Personalized Solutions and Tools for Medication Adherence of Rx Pills
The primary aim of this study is to conduct a 9-patient feasibility and acceptability study of mSMART (with future studies focusing on improved medication adherence).
- Trial name
- mSMART (NCT02072005)
- Testing
- mSMART smartphone application
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Duke University
Diabetes Mellitus
A Smartphone Application to Improve Medication Adherence Among People With Type 2 Diabetes Mellitus in Singapore
Background: Diabetes mellitus (DM) is a major cause of morbidity and mortality worldwide. Long-term glycemic control is important to prevent or delay the onset of DM related complications.
- Trial name
- iADHERE (NCT02105597)
- Testing
- Mobile application
- Where
- Singapore
- Sponsor
- Singapore General Hospital
Surgery, Nurse's Role
Effects of Aromatic Solution Applied After Surgery
Today, surgical applications are used to solve many health problems. In order for the surgical intervention to take place, anesthesia applications are often required.
- Conditions
- Surgery, Nurse's Role, Throat, Sore, Thirst
- Trial name
- NCT05522023
- Testing
- group treated with aromatic solution, group treated with drinking water
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Adrenergic Beta-Antagonists, Stable Angina Pectoris
A Randomized, Two-arm, Open Label Study to evalUate the Effect of a Smart Phone-based Patient Support Tool On Patient AdheRence of Treatment in Stable Angina Patients Prescribed Beta-blockers in China (SUPPORT)
The present study aims to enhance the adherence of beta-blockers by Patient Support Tool through a smart phone application and a wristband, subsequently reduce the risk of angina attacks in patients with stable angina pectoris.
- Conditions
- Adrenergic Beta-Antagonists, Stable Angina Pectoris, Medication Adherence, Mobile Applications
- Trial name
- NCT03794713
- Testing
- Patient support tool
- Volunteers
- 432 people
- Sponsor
- Shenyang Northern Hospital
Schizophrenia, Schizoaffective Disorder
Therapeutic Improvement in People With Schizophrenia Undergoing tACS/CBTp (Transcranial Alternating Current Stimulation Applied Pre-cognitive Behavioral Therapy for Psychosis) Associated to Usual Medication Regimen
The investigators are proposing a new, non-invasive therapeutic model using transcranial alternative current stimulation (tACS), to augment cognitive behavioral therapy for psychosis (CBTp) efficacy in individuals with…
- Trial name
- tACS/CBTpSZ (NCT06889025)
- Testing
- Experimental: tASC/CBTp: gamma band electric stimulation for 20 minutes at the beginning of the CBTp session
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Felicia Iftene
Hemostasis, Surgical Blood Loss
Hemocoll, Avitene, or Bone Wax for Cancellous Bone Bleeding After Single-Ray Amputation
This is a multicentre, prospective, three-arm, parallel-group randomized controlled superiority trial evaluating fibrillar Type-I collagen haemostat (Hemocoll®) FTC, Avitene™ Microfibrillar Collagen Hemostat (MCH), and…
- Conditions
- Hemostasis, Surgical Blood Loss, Amputation Stump, Hemorrhage
- Trial name
- CANHAEM-Ray (NCT07788846)
- Testing
- Hemocoll® Fibrillar type-I collagen haemostat, Bone wax, Avitene™ Microfibrillar Collagen Hemostat
- Where
- 3 sites in India
- Volunteers
- 135 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Drug-induced Liver Injury
Establishment of Drug-induced Liver Injury Databases and Application of Circulating microRNA(miRNA)
The purpose of the study is to establish drug-induced liver injury databases in China, make criteria for Chinese drug-induced liver injury patients and evaluate the application of certain circulating miRNA in diagnosis or…
- Trial name
- NCT02061826
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Beijing Ditan Hospital
Opioid-use Disorder, IV Drug Usage
AWAITS: A Web-based E-health Application for Active Illicit Opioid Users
The purpose of this research study is to: 1. assess how participants like the AWAITS e-health application as measured by their feedback on the intervention 2.
- Conditions
- Opioid-use Disorder, IV Drug Usage, Overdose, Drug Addiction
- Trial name
- AWAITS (NCT03402672)
- Testing
- self-administered, e-health application
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Cincinnati
Hip Fractures (ICD-10 72.01-72.2)
Traumatologic Acute Pain Management With Fentanyl Transdermal Therapeutic System (TTS)
Aim of the study is an examination whether a modified perioperative pain management system, that integrates the 2017 European Society of Anaesthesiology (ESA) guidelines for treatment of postoperative Delirium, can improve…
- Trial name
- NCT04026022
- Testing
- Fentanyl Transdermal System
- Where
- Austria
- Volunteers
- 145 people
- Sponsor
- Medical University of Graz
Contraception
Acceptability of Depo-subQ in Uniject
This is an observational study to assess the experience of current depot medroxyprogesterone acetate (DMPA) intramuscular (IM) clients and providers when they try Depo-subQ in Uniject and offer recommendations for the…
- Trial name
- NCT01667276
- Where
- 2 sites in Senegal, Uganda
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- FHI 360
Colorectal Cancer
Drug Trial to Investigate the Safety and Efficacy of Niclosamide Tablets in Patients With Metastases of a Colorectal Cancer Progressing After Therapy
Phase II trial evaluating the safety and efficacy of oral appliqued niclosamide in patients who are progressive with metachronous or synchronous metastases of colorectal cancer among the previous therapy (Nikolo).
- Trial name
- Nikolo (NCT02519582)
- Testing
- Niclosamide
- Where
- Germany
- Volunteers
- 37 people
- Sponsor
- Charite University, Berlin, Germany
Obesity and Metabolic Syndrome
Auricular Acupressure Integrated With a Smartphone Application for Weight Reduction
The goal of this clinical trial is to learn whether self-administered auricular acupressure integrated with a smartphone application works to reduce weight in patients with obesity accompanied with obesity-related comorbid…
- Trial name
- NCT06744933
- Testing
- Self-administered auricular acupressure integrated with a smartphone application
- Where
- 2 sites in Hong Kong
- Volunteers
- 220 people
- Sponsor
- Tung Wah College
Infertility
The Effect of Telehealth Applications on the Level of Anxiety in the Treatment of Infertility
It is expected that 84% natural pregnancy will occur at the end of the first 12 months of sexual intercourse without the use of contraceptive methods.The lack of natural fertility is under the influence of multiple factors.
- Trial name
- NCT05148273
- Testing
- telenursing
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Perioperative Medication Errors, Perioperative Adverse Medication Events
Usability of a Perioperative Medication-Related Clinical Decision Support Application
The goal of this study is to compare the usability of a novel, medication-related clinical decision support (CDS) application to the current standard medication administration and documentation workflow.
- Trial name
- NCT04988737
- Testing
- Electronic Clinical Decision Support Application
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Intracranial Infection, Central Infection
Concentration Monitoring of Anti-infective Drugs in Human Cerebrospinal Fluid and Its Clinical Application
At least 50 patients with intracranial infection receiving anti-infective drugs such as vancomycin, meropenem, linezolid, cefoperazone sulbactam, ceftazidime and avibactam were included in each group for pharmacokinetic study…
- Trial name
- NCT06729619
- Testing
- The concentration of anti-infective drugs in blood and cerebrospinal fluid will be determined.
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xueyan Cui
Low Back Pain, Mechanical
Effectiveness of Chiropractic Application for Acute Low Back Pain
The aim of this project is to investigate the effectiveness of chiropractic application on patients who have undergone routine medication as a standard hospital treatment for mechanical low-back pain as described in the Clinical…
- Trial name
- NCT04110119
- Testing
- diclophenac sodium (75 mg, IM) and thiocolchicoside (4 mg, IM), Chiropractic Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Medipol University
Tinea Versicolor
Clinical Assessment of Itraconazole Self Nano Emulsifying Drug Delivery System Intermediate Gel
Clinical study for the developed Itraconazole self nano emulsifying drug delivery system intermediate gel was conducted on 30 patients with tinea versicolor infection.
- Trial name
- NCT04110834
- Testing
- itraconazole gel once daily, itraconazole gel twice daily
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sara Botros
Atopic Dermatitis (AD)
Exploratory Clinical Investigation on Neurosensory Responses Via EEG Headband in Adults With Mild to Moderate Atopic Dermatitis After Application of Marketed Product Compared With Placebo (Water Application).
This is a prospective, exploratory, double-blind, single-visit internal validation study designed to evaluate neurosensory responses using electroencephalography head band (EEG) in adult subjects with mild to moderate atopic…
- Trial name
- NCT07333300
- Testing
- Marketed Test Product
- Where
- India
- Volunteers
- 20 people
- Sponsor
- NovoBliss Research Pvt Ltd