Clinical trials: Drug Application
Breast Cancer, Breast Neoplasm
Evaluating an AI-Based Mobile Application for Chemotherapy Support in Breast Cancer Patients
The goal of this clinical trial is to learn if an Arabic-language mobile application that uses artificial intelligence (AI) can help women with breast cancer during chemotherapy.
- Conditions
- Breast Cancer, Breast Neoplasm, Chemotherapy-Related Toxicities, Medication Adherence
- Trial name
- AI-ChemoApp (NCT07273812)
- Testing
- AI-Based Mobile Application for Personalized Chemotherapy Support, Usual Care
- Where
- Iraq
- Volunteers
- 130 people
- Sponsor
- Dena h. Al-Tameemi
Endometriosis
Ultra-Safe Hormonal Strategy: Transdermal Estradiol Added to Progestins for Endometriosis
Endometriosis is a chronic, estrogen-dependent disease affecting women of reproductive age, associated with pelvic pain, infertility, and reduced quality of life.
- Trial name
- TAEDIUMVITAE (NCT07204093)
- Testing
- Drospirenone 4 mg orally, Dienogest 2 mg orally
- Where
- Italy
- Volunteers
- 138 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
GERD (Gastroesophageal Reflux Disease)
Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of the Smartphone Application GERDCare
Adherence to GERD treatment, including medication, diet, and lifestyle, is essential for symptom control and complication prevention, yet adherence rates remain low due to various demographic and clinical factors.
- Trial name
- AppGERD (NCT07125521)
- Testing
- GERCCare mobile app
- Where
- Vietnam
- Volunteers
- 380 people
- Sponsor
- Institute of Gastroenterology and Hepatology, Vietnam
Macular Edema
A Study to Evaluate an Updated Dexamethasone Intravitreal (Into the Eye) Applicator in Adult Participants With Macular Edema Due to Diseases of the Retina
The Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS) Applicator is used to deliver an implant with medicine to the eye. AbbVie is updating the DEX PS DDS Applicator.
- Trial name
- NCT04976777
- Testing
- Updated DEX PS DDS Applicator, Approved DEX PS DDS Applicator, Dexamethasone
- Where
- 7 sites in United States
- Volunteers
- 54 people
- Sponsor
- AbbVie
Rational Drug Use
Rational Drug Use in Elderly People
Irrational drug use, which is an important public health problem worldwide, is common in the elderly. While irrational drug use negatively affects all age groups, it poses a significant threat to the health of the elderly.
- Trial name
- NCT05397847
- Testing
- Education, Rational Drug Use Guide, Medicine Box
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Drug Compliance, Patient Acceptance of Health Care
Effect of Mobile Application Usage on Drug Compliance After Thyroidectomy
In patients who have undergone thyroidectomy surgery, drug use will be reminded with a mobile application in the postoperative period.
- Trial name
- NCT05503576
- Testing
- reminder mobile application
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Medication Adherence
Smart About Meds (SAM) RCT
Introduction: Almost half of patients discharged from hospital are re-admitted or return to the emergency department (ED) within 90 days.
- Trial name
- NCT05371548
- Testing
- SAM mobile application
- Where
- Canada
- Volunteers
- 3,250 people
- Sponsor
- Robyn Tamblyn
Drug Use Disorders, Illicit Drug Use
An Initial Study of the Implementation of Digital Therapeutics for Substance Use Disorders in Primary Care
The DIGITS Trial addresses a critical knowledge gap: How to best implement digital treatments for opioids and other substance use disorders in primary care.
- Conditions
- Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
- Trial name
- DIGITS Pilot (NCT04907045)
- Testing
- Health Coaching, Practice Facilitation, Standard Implementation
- Where
- United States
- Volunteers
- 1,552 people
- Sponsor
- Kaiser Permanente
Warts
Four Week Safety and Efficacy Study With a Topical Gel to Treat Common Warts in Pediatric Subjects
The primary purpose of this study is to evaluate the effectiveness in pediatric subjects of three different strengths of resiquimod gel applied to common wart(s) three times a week for four weeks.
- Trial name
- NCT00116675
- Testing
- Resiquimod
- Where
- 10 sites in United States
- Volunteers
- 84 people
- Sponsor
- Graceway Pharmaceuticals, LLC
Opioid Use Disorder
Mobile Peer Support for OUD Recovery
The COVID-19 pandemic puts individuals recovering from opioid use disorders (OUDs), an already vulnerable population, at increased risk of overdose due to decreased access to treatment, decreased social support, and increased…
- Trial name
- MPS (NCT05405712)
- Testing
- Mobile Phone App
- Where
- 2 sites in United States
- Volunteers
- 1,300 people
- Sponsor
- Brown University
Rhumatoid Arthisis, Spondyloarthritis (SA)
Efficacy of a Self-Management Smartphone App to Improve Safety Skills in Patients With Inflammatory Arthritis
Rheumatoid arthritis (RA) and spondyloarthritis (SpA), including psoriatic arthritis (PsA), are chronic painful diseases that impair quality of life.
- Conditions
- Rhumatoid Arthisis, Spondyloarthritis (SA), Psoriatic Arthritis (PsA)
- Trial name
- RHUMATOSMART (NCT07460739)
- Testing
- SFR application
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension, Dyslipidemia
A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors
The investigators will conduct a feasibility and pilot efficacy randomized controlled trial to test the usability and user satisfaction of an evidence-based digital health tool the investigators developed for clinicians to use to…
- Conditions
- Hypertension, Dyslipidemia, Diabetes Mellitus, Obesity
- Trial name
- P3-EX (NCT07238556)
- Testing
- Experimental - 12 Week P3-EX Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants, Active Control - 12 Week ACSM-PAVS Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants
- Where
- 3 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Connecticut
Gastrointestinal Surgery, Mirabilite
External Application of Mirabilite to Promote Recovery in Patients After Gastrointestinal Surgery
This study evaluates the efficacy and safety of topical Mirabilite (sodium sulfate) application for managing postoperative outcomes in patients undergoing gastrointestinal cancer surgery.
- Conditions
- Gastrointestinal Surgery, Mirabilite, Surgical Site Infection, Postoperative Gastrointestinal Dysfunction
- Trial name
- NCT06696729
- Testing
- Topical Mirabilite Application for Postoperative Gastrointestinal Patients, Standard Postoperative Care for Gastrointestinal Patients
- Where
- China
- Volunteers
- 301 people
- Sponsor
- Nanchang University
Cancer
Validation of an Electronic Remote Toxicity Management System in Cancer Patients
To assess the psychometric properties (validity, reliability and responsiveness) of the QuestOnco tool, an electronic Remote Toxicity Management System, in adult cancer patients receiving an active anti-cancer treatment.
- Trial name
- eRToMSy (NCT04915274)
- Testing
- uses of an application
- Where
- France
- Volunteers
- 134 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
HIV Infections
Study of Tenofovir Disoproxil Fumarate (TDF) for Prevention of HIV
This Phase 2a study involving Tenofovir Disoproxil Fumarate (TDF) will provide extended safety data for high-risk men. Secondarily, the study will assess the feasibility of conducting the trial and evaluate the preliminary…
- Trial name
- NCT00122512
- Testing
- Tenofovir Disoproxil Fumarate
- Where
- Malawi
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- FHI 360
Orofacial Pain
The Use of tDCS in the Orofacial Pain
The trial´s main goal is to explore the use of transcranial direct current stimulation (tDCS) as a treatment option for persons suffering from orofacial pain.
- Trial name
- NCT05584384
- Testing
- Transcranial Direct Current Stimulation
- Sponsor
- Charles University, Czech Republic
Adolescent Anorexia Nervosa
Treatment Trial of Thermoregulatory Disturbances in Adolescent Anorexia Nervosa Patients With Either Ginger Powder Footbaths or Warm Water Footbaths
A study to explore whether warm water footbaths with added ginger powder can improve thermoregulatory processes in adolescent anorexia nervosa patients and provide them with an increase in subjective feeling of warmth.
- Trial name
- NCT03886207
- Testing
- ginger powder footbath, warm water only footbath
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Asthma
Assessment of a Mobile Intervention to Increase Adherence to Asthma Medication Among Adolescents
The purpose of this study is to assess the use of a mobile health intervention to improve adherence to asthma medication among adolescents.
- Trial name
- NCT02426814
- Testing
- Inhaler sensor, Mobile application for asthma adherence
- Where
- United States
- Sponsor
- CoheroHealth
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of a Mitopure Topical Product Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of multiple topically applied test articles (containing different concentrations of Mitopure), in a shared panel of healthy volunteers by…
- Trial name
- GLOW-Safety (NCT05079607)
- Testing
- Mitopure Topical Formula 1, Mitopure Topical Formula 2
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
The Study Goal is to Assess the Introduction of Sustainable Family Planning/Reproductive Health Information and Services Through, Land O' Lakes-supported Dairy Cooperatives
Family Planning Through Dairy Cooperatives
This observational study will assess a model for providing family planning through quarterly events organized by dairy cooperatives supported by Land O'Lakes in Kenya.
- Trial name
- NCT01226433
- Where
- Kenya
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- FHI 360