Clinical trials: Drug Application
Onychomycosis
Pharmacokinetics and Safety Study of ME1111 in Moderate to Severe Onychomycosis Patients
This study is Randomized, Double-Blind, Vehicle-Controlled, Multiple-Dose Study. The purpose is to determine the safety, tolerability, systemic exposure and pharmacokinetics of ME1111 after repeated daily topical application of…
- Trial name
- NCT01841996
- Testing
- ME1111 solution, Vehicle Solution
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Meiji Seika Pharma Co., Ltd.
Seasonal Allergic Rhinitis
New Nasal Applicator / New Formulation - User Study
The purpose of this study is to compare the efficacy of once daily dosing with Rhinocort Aqua (new formulation) against Rhinocort Aqua (current formulation) and placebo in reliving the symptoms of seasonal allergic rhinitis (SAR).
- Trial name
- NCT00641979
- Testing
- budesonide
- Volunteers
- 200 people
- Sponsor
- AstraZeneca
Mastitis Acute Female
The Effect of Chinese Herbal Medicine for Reducing the Application of Antibiotics in the Treatment of Acute Mastitis
The object of the study is to evaluate the effect of Pugongying (Herba Taraxaci) Granules to reduce the application of antibiotics for women with acute mastitis.
- Trial name
- NCT03756324
- Testing
- CHPM (Chinese Herbal Patent Medicine ), Antibiotics Cefdinir Capsules, Education
- Where
- 3 sites in China
- Volunteers
- 306 people
- Sponsor
- Beijing University of Chinese Medicine
Healthy
Clinical Adhesion Study Between ZTlido 1.8% and Three Over-the-counter External Analgesic Lidocaine-containing Patches
The study is designed to evaluate and compare the clinical adhesion performance of the ZTlido (Lidocaine Topical System) 1.8% of Scilex Pharmaceuticals Inc.
- Trial name
- NCT05106400
- Testing
- ZTlido (Lidocaine Topical System) 1.8%, Salonpas (Lidocaine Patch 4%), Aspercreme (Lidocaine Patch 4%)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Scilex Pharmaceuticals, Inc.
Asthma
Monitoring of Patients With Asthma Performed by a Clinical Pharmacist Using a Mobile Application
Asthma is a chronic inflammatory disease that affects the lungs. In Brazil it is responsible for about 4 to 8 deaths per day. Pharmacotherapeutic follow-up programs for people with asthma have a positive impact on treatment…
- Trial name
- NCT05503342
- Testing
- Mobile Application, Asthma control assessment
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Rafael Stelmach
Healthy
From FAST to FAST BEE - Video-Based Stroke Mnemonic Pilot
This online study evaluates immediate learning outcomes after viewing a short animated FAST BEE stroke-education video (1 minute 51 seconds).
- Trial name
- FAST BEE (NCT07440602)
- Testing
- FAST BEE Stroke Education Video (1 minute 51 seconds)
- Where
- India
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Acne Vulgaris
Effect of Samples on Acne Treatment With Epiduo® Gel
The purpose of this study is to compare adherence to treatment and efficacy with Epiduo® Gel in patients with mild to moderate acne who receive a medication sample and instructions on proper application with their stock size…
- Trial name
- NCT01504204
- Testing
- Adapalene + benzoyl peroxide samples, Adapalene + benzoyl peroxide from standard tube
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wake Forest University
Prostate Cancer, Health Knowledge, Attitudes, Practice
Developing and Validating Health Education Module for Prostate Cancer Prevention Behavior in Iraqi Male University Staff
Research Objectives To compare the effectiveness of the education modules on the knowledge, attitude, and practice of male university staffs towards prostate cancer prevention behaviors by comparing the pre- and post-test of…
- Trial name
- NCT07878663
- Testing
- Web Application Health Education Module
- Where
- Iraq
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Chronic Disease
Effects of the Clinical Application of Traditional, Complementary and Integrative Medicine (TCIM) Procedures During Inpatient Stays in Germany
The aim of this healthcare research project is to evaluate the effects of routine inpatient TCIM (Traditional, Complementary and Integrative Medicine) care in Germany.
- Trial name
- Minerva (NCT07040475)
- Testing
- Inpatient TCIM therapy
- Where
- 3 sites in Germany
- Volunteers
- 2,500 people
- Sponsor
- Charite University, Berlin, Germany
Medication Overuse Headache
Personalized Pulsed Radiofrequency of the Greater Occipital Nerve for Medication Overuse Headache
This study evaluates a novel treatment approach for medication overuse headache (MOH) using greater occipital nerve pulsed radiofrequency (GONPRF).
- Trial name
- PRIMOGON (NCT07360782)
- Testing
- Greater Occipital Nerve Pulsed Radiofrequency, Standard care
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Critical Illness, Infections, Respiratory
Using Telemedicine to Optimize Teamwork and Infection Control of Critical and Highly-infectious Patients in an Emergency Department
Since 2000, various emerging infectious diseases have repeatedly caused serious impact on the health of the global population and the healthcare systems.
- Conditions
- Critical Illness, Infections, Respiratory, Emergency Service, Hospital, Telemedicine
- Trial name
- NCT04591873
- Testing
- telemedicine, traditional communication tools
- Where
- Taiwan
- Volunteers
- 74 people
- Sponsor
- National Taiwan University Hospital
Rotator Cuff Tear
Application of Shock Wave Technique in Conservative Treatment of Rotator Cuff Tear
This study is a prospective cohort study and is a single-center clinical trial. Sample: This study will enroll about 22 patients from the Department of Sports Medicine and rehabilitation outpatient department of Beijing Third…
- Trial name
- NCT06587009
- Testing
- Shock wave therapy, Conventional conservative treatment
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Peking University Third Hospital
Epilepsy
Pharmacogenetics-Based Study on Individualized Use of Sodium Valproate
Sodium valproate (VPA) is a first-line prescription drug widely used in the treatment of epilepsy. However, in clinical applications, it has been found that there is a large individual variation in the blood concentration of VPA.
- Trial name
- NCT07046676
- Testing
- sodium valproate
- Where
- China
- Volunteers
- 312 people
- Sponsor
- The First Affiliated Hospital of University of South China
Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ), Oxygen
Topical Oxygen Therapy for BRONJ
A randomized clinical trial comparing Blue®m oral gel and autologous PRF membrane as adjuncts to surgical debridement in BRONJ/MRONJ patients.
- Conditions
- Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ), Oxygen, Topical Administration, Wound Healing
- Trial name
- OXY-BRONJ Tria (NCT07725107)
- Testing
- Topical Blue®m application, PRF membrane placement
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Mansoura University
Cancer
CAM in Hospice Palliative Care in Taiwan
The study aims to explore the effects of silver spike point (SSP) treatment on common symptoms including pain, breathlessness, nausea/vomiting, dry mouth etc. of terminal cancer patients.
- Trial name
- NCT02663063
- Testing
- SSP treatment
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Arthroscopy
Comparison the Effects of 3 Different Intraarticular Ketamine Doses on Postoperative Pain.
the aim is to compare the effects of two different doses of intraarticular ketamine on postoperative pain scores and analgesic requirements.in knee artroscopy
- Trial name
- NCT03955809
- Testing
- Ketamine 0.5, Ketamine 1, % 0.9 NaCl
- Volunteers
- 75 people
- Sponsor
- Balikesir University
Tooth Extraction Status Nos, Post Operative Pain
A Mobile Application for Post-op Analgesic Consumption
Surgical extraction of third molars is one of the most common outpatient procedures performed by oral surgeons. The prescription of postoperative narcotic and NSAID analgesics is the standard of care practice to relieve symptoms…
- Conditions
- Tooth Extraction Status Nos, Post Operative Pain, Patient Satisfaction, Narcotic Use
- Trial name
- NCT03197311
- Testing
- Mobile app
- Where
- United States
- Sponsor
- Boston University
Respiration Disorders
To Identify if a COPD Self-management App Can Safety and Appropriately Identify When Patients Are Not on the Best Medication Plan for Their COPD Symptoms and Support Their COPD Management.
Although COPD cannot be cured, managing COPD can help reduce symptoms control, slows progression of the disease, and may improve the quality of life.
- Trial name
- mySmartCOPD (NCT07797985)
- Testing
- MMH-LAB1 app
- Where
- United Kingdom
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Oral Cancer, Health Education, Community
Testing and Comparing the Impacts of Mhealth-Based and Web-Based Education on Oral Cancer
Introduction: Oral cancer is a malignant neoplastic disease affecting the lip, oral cavity (mouth) and/or the oropharynx. Despite the intense and diverse public health interventions on oral cancer prevention, the global…
- Conditions
- Oral Cancer, Health Education, Community, Digital Intervention, MHealth Application
- Trial name
- NCT06711848
- Testing
- A web-based educational intervention on oral cancer, A mobile health app-based educational intervention on oral cancer
- Where
- 5 sites in India, Nigeria and 2 more
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Rwanda
Traditional Chinese Medicine
the Effect of Acupoint Application Combined With Ear Acupoint Embedding in Patients After Esophageal Cancer Surgery
To study the effect of acupoint application combined with ear acupoint seeding on the discomfort symptoms of nasal catheter in patients after esophageal cancer surgery
- Trial name
- NCT05151068
- Testing
- traditional nursing method, Precise acupoint application combined with ear acupoint embedding nursing program
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital of Soochow University