Clinical trials: Drug Application
Medication Adherence, Retention in Care
An Avatar-based Mobile Phone Intervention to Promote Health in African American MSM
The investigators propose to determine the efficacy of "My Personal Health Guide," a theory-based innovative talking relational human Avatar mobile phone application to engage HIV-positive AAMSM in adherence and retention in…
- Trial name
- NCT04217174
- Testing
- My Personal Health Guide, My Personal Food Guide
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- University of Illinois Chicago
Palmar-Plantar Erythrodysesthesia
The Topical Application of Vitamin B6 in Palmar-Plantar Erythrodysesthesia
The study is designed to test the effectiveness of topical B6 cream in patients that developed Palmar-Plantar Erythrodysesthesia (Hand foot syndrome).
- Trial name
- HFSB6 (NCT02625415)
- Testing
- Vitamin B6 cream
- Where
- 2 sites in Cyprus
- Volunteers
- 54 people
- Sponsor
- Cyprus University of Technology
Knowledge, Attitudes, Practice, Injection Site Reactions
Study to Evaluate the Need of Needle Change for Application of Intramuscular, Subcutaneous and Intradermal Injection.
Comparing the pain intensity on a numeric scale (0-10) with intramuscular and subcutaneous injection between a retractable fixed syringe needle and the technique involving needle exchange; Comparing bruise formation following…
- Trial name
- NCT01271608
- Testing
- needle exchange
- Where
- Brazil
- Volunteers
- 1,240 people
- Sponsor
- Hospital M'Boi Mirim
Antibiotics
Standardized Clinical Application of Antibacterial/Anitifungal Drugs
The purpose of this real world study is to observe the clinical status for standardized using of antibacterial/anitifungal drugs in patients with infection,and to evaluate the efficacy and safety of anti-infection therapy.
- Trial name
- NCT04966390
- Volunteers
- 5,000 people
- Sponsor
- Peking University People's Hospital
Renal Insufficiency, Chronic, Hypertension
Mobile Health Technology for Chronic Kidney Disease Patients: Medication Management
Patients with complex, long-lasting conditions such as chronic kidney disease (CKD) often take multiple medications and frequently have serious medication problems, arising from poor communication between doctors and patients.
- Conditions
- Renal Insufficiency, Chronic, Hypertension, Medication Reconciliation, Mobile Applications
- Trial name
- NCT02905474
- Testing
- Usual Care, Integrated mobile medication app, Commercially available mobile medication app
- Where
- Canada
- Volunteers
- 182 people
- Sponsor
- University Health Network, Toronto
Myasthenia Gravis
TCM Tongue Diagnosis and Syndrome Differentiation in Myasthenia Gravis Compared to Healthy Controls
Myasthenia gravis primarily results from neuromuscular junction dysfunction and damage, leading to chronic muscle weakness. While combined traditional and Western medicine treatments are now common, TCM tongue diagnosis remains a…
- Trial name
- NCT06754020
- Testing
- Heart Rate Variability,HRV - ANSWatch, Traditional Chinese Medicine Tongue Imaging
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yi Ting Yeh
Epilepsy, Seizure
AI-Based Mobile Intervention on Medication Non-Adherence and Transition
This study aims to examine whether the AI-personalized version of the Medilepsy® app is more effective than the non-AI (standard version without AI personalization) can improve key outcomes, such as medical adherence and…
- Trial name
- NCT07445074
- Testing
- Medilepsy® Chatbot AI-Enhanced, Medilepsy® Chatbot Standard
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Central Florida
Peripheral Arterial Disease
PacLitaxel Eluting Balloon Application In Sfa In Stent Restenosis
Nowadays, stenting is became a standard of care in revascularization for superficial femoral artery (SFA) atherosclerotic lesions. However, the Achilles' heel of this technique remains in-stent restenosis (ISR).
- Trial name
- PLAISIR (NCT01587482)
- Testing
- PacLitaxel Eluting Balloon Application
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Nantes University Hospital
Foot Ulcer, Diabetic Foot
EZCast-DFU Study With Portal for Application of Topical Medications
This study is designed to evaluate the ability to modify a contact cast system so that topical medications can be applied daily to an underlying wound in patients with diabetic plantar ulcers.
- Trial name
- EZCast-DFU (NCT02131961)
- Testing
- Collagenase ointment, Modified Contact Cast System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Miami
Acute Pancreatitis
Tongfu Qinghua Decoction Enema and Ruyi Jinhuang Powder for Acute Pancreatitis
Acute pancreatitis is an inflammatory condition that commonly causes abdominal pain, abdominal distension, impaired gastrointestinal function, and elevated pancreatic and inflammatory biomarkers.
- Trial name
- NCT07712081
- Testing
- Tongfu Qinghua Decoction Enema, Ruyi Jinhuang Powder External Application, Conventional Medical Treatment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Third Affiliated Hospital of Wenzhou Medical University
Atopic Dermatitis (AD)
Topical Chinese Medicine and Exosome Mechanisms for Atopic Dermatitis
The goal of this clinical trial is to learn if menthol works to relieve pruritus in atopic dermatitis. The primary objectives are to evaluate the safety and clinical efficacy of menthol-containing gloves and foot-covers…
- Trial name
- NCT07693400
- Testing
- menthol-based hand and foot gloves
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Taiwan Municipal An-Nan Hospital-China Medical University
PreDiabetes
The Effect of Traditional Chinese Medicine Regimen-based Lifestyle Mobile Health APP in Prediabetes
Prediabetes is a major risk factor for diabetes. The Lifestyle Modification Mobile Health Application (APP) could not only help to decrease blood sugar among individuals with prediabetes but it could also prevent a later…
- Trial name
- NCT04096989
- Testing
- Traditional Chinese medicine regimen-based lifestyle mobile health APP, Lifestyle mobile health APP
- Where
- Taiwan
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Human Immunodeficiency Virus, Tuberculosis
Usability Study of IeHS in Indonesia
Technology that has a particular focus on patients' needs and ease-of-use and -access plays a significant role in the development of e-health and m-health.
- Conditions
- Human Immunodeficiency Virus, Tuberculosis, Interpersonal Relations, Mobile Phone Use
- Trial name
- NCT04179344
- Testing
- Integrated e-healthcare services (IeHS) web-based app
- Where
- 3 sites in Indonesia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bekasi City Public Hospital
Adherence to Medication Regime, Cancer
Mobile Application for Improving Symptoms and Adherence to Oral Chemotherapy in Patients With Cancer
Many people treated for cancer receive oral chemotherapy medications for their illness. This means that much of their cancer care occurs at home, away from a traditional oncology care setting.
- Trial name
- NCT02157519
- Testing
- Mobile Application Intervention
- Where
- 3 sites in United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Psychosis, Schizophrenia
ReMindCare App for Patients From First Episode of Psychosis Unit.
ReMindCare is an app designed by the Unit of Psychiatry at the Clinical Hospital of Valencia in liaison with the Polytechnic University of Valencia.
- Conditions
- Psychosis, Schizophrenia, Psychotic Disorders, Delirium
- Trial name
- NCT03807388
- Testing
- ReMindCare Intervention Group, Treatment as Usual
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Instituto de Investigacion Sanitaria INCLIVA
Tympanic Membrane Perforation
Insulin Intratympanic Application
The objective of the present study was to study the impact of insulin insitu-gel formulation on healing progress after surgical procedures for treatment of dry tympanic membrane perforation for at least three consecutive months.
- Trial name
- NCT07535827
- Testing
- Insulin (Humulin), foam
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Deraya University
Breast Cancer, Narrative Medicine
New Digital Person-based Care Model in Patients With HER2-negative Advanced Breast Cancer
The goal of the InPerson study is to employ all resources in a digital listening platform to benefit the quality of life of patients (QoL) with advanced HER2-negative breast cancer.
- Conditions
- Breast Cancer, Narrative Medicine, HER2-negative Breast Cancer, Patient Satisfaction
- Trial name
- InPERSON (NCT06348654)
- Testing
- introduction of digital listening may improve the quality of life of patients withe breast cancer
- Volunteers
- 50 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Inhibition, Induction
Pharmacokinetic Interactions of Metamizole (Dipyrone) in Healthy Subjects
Investigators conducted a single center, two-phased, open, controlled pharmacokinetic study to investigate the drug-drug interaction potential of metamizole. For this reason, healthy male volunteers were screened.
- Conditions
- Inhibition, Induction, Drug-Drug Interaction
- Trial name
- NCT03990129
- Testing
- Metamizole
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Complications, Antibiotic Reaction
Complications After Lower Third Molar Surgery
Surgical removal of impacted mandibular wisdom teeth is a frequent intervention, usually accompanied by unpleasant sequelae (pain, swelling and trismus) in the postoperative period, sometimes even with possibly serious…
- Conditions
- Postoperative Complications, Antibiotic Reaction, Antibiotic Side Effect, Antibiotic Resistant Infection
- Trial name
- NCT05027893
- Testing
- Moxifloxacin 400 mg Oral Tablet, Cefixime 400 mg Oral Tablet
- Where
- Serbia
- Volunteers
- 157 people
- Sponsor
- University of Novi Sad
HIV Infection, HIV Infections
Integration of Family Planning and HIV Services in Tanzania
HIV positive women and couples have broad reproductive health needs that are not always met within HIV services. The integration of family planning (FP) services into Tanzania's HIV Care and Treatment Clinics (CTC) will address…
- Trial name
- NCT00941876
- Testing
- Facilitated Referral
- Where
- Tanzania
- Volunteers
- 864 people
- Sponsor
- FHI 360