Clinical trials: Drug Application
Ulcerative Colitis
Improving Knowledge of Medication in Ulcerative Colitis With an Iphone Application
The purpose of this study is to assess an iPhone application to increase adherence to maintenance medications in subjects with ulcerative colitis.
- Trial name
- NCT02120391
- Testing
- iPhone Application
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Wisconsin, Madison
Wound Healing, Diabetic Foot
Clinical Study Evaluating Wound Closure With Endoform™ and Symphony™
Study will evaluate the performance and safety of Endoform™ Natural and Endoform™ Antimicrobial in conjunction with Symphony™ in the treatment of chronic non-healing diabetic foot ulcers after 12 weeks of treatment.
- Conditions
- Wound Healing, Diabetic Foot, Chronic Foot Ulcer, Foot Ulcer
- Trial name
- NCT06035523
- Testing
- Endoform™ Antibacterial, Endoform™ Natural, Symphony™
- Where
- 4 sites in United States
- Volunteers
- 44 people
- Sponsor
- Aroa Biosurgery Limited
Metastatic Castration-resistant Prostate Cancer
[Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application
Phase 1: The objective of the Phase 1 part of the clinical trial is to verify safety and tolerability (dose-limiting toxicity [DLT], maximum tolerated dose [MTD]) of a single 3.7 Giga-Becquerel (GBq) dose with the potential for…
- Trial name
- LUCIDA (NCT05458544)
- Testing
- [177Lu]Ludotadipep 3.7 GBq
- Where
- 4 sites in United States
- Volunteers
- 26 people
- Sponsor
- FutureChem
Pressure Injury
Mobile Education for Pressure Injury Prevention and Caregiver Support
This study is a randomized controlled trial designed to evaluate the effectiveness of a nurse-led, mobile health (mHealth) education program for informal caregivers of bedridden patients receiving home healthcare services.
- Trial name
- MOBILE-PIP (NCT07565233)
- Testing
- Mobile Life Without Pressure Injury Application
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Gündem Yakan Şahin
Dentin Sensitivity
Comparison of Dentin Hypersensitivity Reduction Over a 1-month Period
Here we assessed the clinical effectiveness of Gluma, fluoride varnish, and the Tetric N-Bond one-step self-etch system in alleviating DH instantly and over 1 month, after a single topical application.A randomized, double-blind…
- Trial name
- NCT04351412
- Testing
- Gluma, fluoride varnish, Tetric N-Bond self-etch adhesive
- Where
- Saudi Arabia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Atherosclerosis
Improving Adherence to Statin Therapy Through a Medication Management Application
Interventional study to compare standard of care vs standard of care plus the use of a medication therapy management smartphone app (mediteo m+, Mediteo GmbH, Heidelberg) in patients with atherosclerotic cardiovascular disease…
- Trial name
- STAPP (NCT05777655)
- Testing
- Medication management app (mediteo m+, Mediteo GmbH, Heidelberg)
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- University Hospital, Essen
Digital Technology, Technology Addiction
The Effect of Health Education Based Laughter Yoga Applied to Adolescents on Stress and Digital Gaming Habits
Adolescents may turn to digital games as a coping mechanism for stress, which can lead to addiction and various health problems.
- Conditions
- Digital Technology, Technology Addiction, Internet Addiction Disorder, Laughter Yoga
- Trial name
- Digital Habits (NCT07032090)
- Testing
- Health education, Laughter Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Radiation Disease, Cognitive Impairment
Early Application of Memantine and Pioglitazone to Protect Cognitive Function After Radiotherapy
This clinical trial aims to evaluate the efficacy of early intervention with Memantine and Pioglitazone in preventing Radiation-Induced Brain Injury (RIBI) in patients undergoing cranial radiotherapy.
- Conditions
- Radiation Disease, Cognitive Impairment, Drug Effect
- Trial name
- NCT06594172
- Testing
- Memantine Oral Tablet, Pioglitazone 15mg, Hippocampal avoidance whole-brain radiotherapy (HA-WBRT)
- Volunteers
- 67 people
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Bleeding After GI Endoscopy
Endoscopic Application of Hemostatic Drug Powder in Lower Gastrointestinal Bleeding: A Pilot Study
This clinical trial will enroll patients at National Cheng Kung University Hospital. All patients who are hospitalized for lower gastrointestinal bleeding and undergo colonoscopy will be invited to participate.
- Trial name
- NCT07679139
- Testing
- Tranexamic acid and sucralfate powder spray, Standard endsocopic hemostasis
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Incontinence-associated Dermatitis
How Wet Pads Affect Elderly Skin: Measuring Changes in the Skin Barrier
The main aim of this study is to describe the effects of dry or wet incontinence pad material on the skin barrier function by measuring the changes of the stratum corneum on healthy participants due to the application of pads…
- Trial name
- DROPBOX (NCT07164898)
- Testing
- Test patches
- Where
- Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Essity Hygiene and Health AB
Gestational Diabetes Mellitus in Pregnancy, Type 2 Diabetes
Mobile App Logging for Diabetes in Pregnancy
To determine the effect of using a mobile app versus paper logs on compliance and percentage in range blood sugars in monitoring blood sugar in pregnant women with diabetes.
- Trial name
- NCT06005987
- Testing
- OneTouch Reveal application
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Carolyn Zahler-Miller
Type 2 Diabetes Mellitus (T2DM), Obesity (Disorder)
Digital Dietary Intervention for Patients Receiving GLP-1 Receptor Agonist Therapy
The goal of this clinical trial is to learn whether adding the NutriSteppe digital dietary intervention to routine medical care improves metabolic health in adults aged 21 to 65 years with type 2 diabetes mellitus, obesity, or…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Obesity (Disorder), Overweight, Metabolic Syndrome
- Trial name
- NutriSteppe (NCT07728669)
- Testing
- NutriSteppe Digital Dietary Intervention
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- Kazakh Academy of Nutrition
Increased Production of Tears
Will a Hands on Technique Applied to the Face Increase the Tear Production in Participants
The goal of this interventional study is to learn if a hands on technique will increase tear production in patients aged 45 and younger, without a history of eye issues.
- Trial name
- NCT07632183
- Testing
- sphenopalatine ganglion release
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Dementia, Alzheimer Disease
Long-term Use of Galantamine Versus Nootropics (Memory Enhancing Drugs) in Patients With Alzheimer's Dementia Under Conditions of Daily Routine
The main objective of this non-interventional study was to document the long-term application of galantamine and nootropics (memory enhancing drugs) over a period of 1 year under conditions of daily routine.
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular
- Trial name
- NCT01009476
- Testing
- Galantamine, Nootropics (ginkgo biloba, nicergoline, piracetam, or others)
- Volunteers
- 1,134 people
- Sponsor
- Janssen-Cilag G.m.b.H
Breast Cancer, Cancer
Digital Patient Support Program for Self-efficacy and Medication Adherence in Women on Adjuvant Endocrine Treatment for Breast Cancer
This is a randomized, controlled study to assess the effect of Sidekick Health's digital program on self-efficacy and medication adherence in breast cancer patients prescribed adjuvant anti-hormonal treatment.
- Trial name
- NCT06989450
- Testing
- Sidekick digital patient support program for patients with breast cancer, Standard of care for breast cancer patients
- Where
- Iceland
- Volunteers
- 140 people
- Sponsor
- Sidekick Health
Heart Failure
Use of Telemonitoring to Facilitate Heart Failure Medication Titration
Heart failure (HF) is a common diagnosis with high prevalence, reduced life expectancy and a significant clinical and economic burden.
- Trial name
- Medly Titrate (NCT04205513)
- Testing
- Medly
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- University Health Network, Toronto
COVID-19
Study of Monoclonal Antibodies for Early Etiotropic Therapy for Coronavirus Infection Caused by the SARS-CoV-2 Virus
Open prospective non-comparative study of safety and tolerability of the drug (GamCoviMab) with the description of the parameters of the therapeutic efficacy in patients with confirmed COVID-19 diagnosis.
- Trial name
- NCT05729360
- Testing
- GamCoviMab
- Volunteers
- 30 people
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Migraine
Efficacy of Smartphone Based Digital Application in Improving Headache Related Parameters in Patients With Migraine
Migraine is a common headache disorder and affects 1 in 5 adults during their lifetime. It is a disorder which leads to significantly impaired quality of life, absence from work, loss of productivity in workplace and reduced…
- Trial name
- NCT04984720
- Testing
- Smartphone based digital application
- Where
- India
- Volunteers
- 403 people
- Sponsor
- All India Institute of Medical Sciences