Clinical trials: Drug Delivery System
Prevention of Diseases of the Musculoskeletal System
Testing the Effectiveness and Safety of a Passive Industrial Exoskeleton for Back Support
This research will provide data on evaluation of the effectiveness and safety of using a passive exoskeleton designed to reduce the negative impact of static and dynamic loads associated with body tilts, lifting and holding…
- Trial name
- NCT04514172
- Testing
- Passive industrial exoskeleton for back support, The protocol will be performed without exoskeleton
- Where
- Russia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health"
Amyotrophic Lateral Sclerosis (ALS)
Circulating Biomarker for Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis (ALS) is a rare disease with a worldwide incidence of 2-3 cases per 100,000 individuals/year and it is characterized by progressive neurodegeneration of motor neurons.
- Trial name
- NCT03088839
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Low Level Laser Therapy, Healthy
Effect of GaAlAs 940 Laser on Pain and Wound Healing After Free Gingival Graft
This randomized controlled clinical trial aims to evaluate the biomodulatory effects of a 940-nm GaAlAs diode laser on postoperative pain control and wound healing at the palatal donor site following free gingival graft…
- Conditions
- Low Level Laser Therapy, Healthy, Postoperative Pain Management, Wound Healing
- Trial name
- NCT07308912
- Testing
- 940 nm GaAlAs diode laser, palatal stent
- Where
- Vietnam
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Muscular Atrophy, Spinal
Bioavailability and Bioequivalence of Two Risdiplam Tablets in Healthy Participants
The study is a randomized, single oral dose, crossover study in up to three parts to investigate the relative bioavailability and bioequivalence of two different formulations of risdiplam 5 mg (dispersible tablets) versus the…
- Trial name
- NCT04718181
- Testing
- risdiplam, omeprazole
- Where
- 4 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Type 2 Diabetes
Bias Source of Signal in SCOUT DS
The primary objective is to identify device characteristics, components or subsystems that manifest as screening score bias in SCOUT DS.
- Trial name
- BSOS (NCT01550328)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- VeraLight, Inc.
Idiopathic Inflammatory Myopathies, Physical Activity
Physical Training in Patients With Idiopathic Inflammatory Myopathies
Physical training may improve physical capacity and health parameters in various systemic autoimmune diseases, including idiopathic inflammatory myopathies.
- Trial name
- NCT03092167
- Testing
- Physical exercises
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Postural Tachycardia Syndrome
Adrenocorticotropic Hormone Stimulation in Postural Orthostatic Tachycardia Syndrome (POTS)
This study is to determine different chemical levels in the blood during a low salt diet. This study will compare normal volunteers to those with Postural Tachycardia Syndrome (POTS)
- Trial name
- NCT01764711
- Testing
- Cosyntropin administration
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Systemic Lupus Erythematosus
Serum Levels of Angiotensin Converting Enzyme in Systemic Lupus Erythematous Patients
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease that involve many different organs and display a variable clinical course.The prevalence of SLE varies across gender, race/ethnicity, and geographic…
- Trial name
- NCT05516511
- Testing
- Angiotensin Converting Enzyme test
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sohag University
Concussion
EEG Diagnostic for Repetitive Sub-concussive Head Impacts
The purpose of this study is to develop a diagnostic algorithm to help with the detection, diagnosis, and monitoring of sub-concussive head impacts.
- Trial name
- NCT05562544
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
All
Amish/Mennonite Research Contact Registry
The purpose of this registry is to find members of the Plain Community who are interested in participating in future medical research studies.
- Trial name
- NCT02990572
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cryotherapy Effect
The Effect of Brief Skin Cooling on Isometric Muscle Strength
There is sympathetic innervation of the muscular spindle. The application of cold to the skin provides an increase in sympathetic activity.
- Trial name
- NCT06079437
- Testing
- Cheer, The cold pressure test
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Spinal Cord Injuries, Rehabilitation
Study on Rehabilitation Exercise Program for Community-based Spinal Cord Injury Patients
In the case of spinal cord injury, patients have shown a passive attitude towards participating in leisure sports or exercise programs, and there is a lack of suitable guidelines or experience in the local community for coaching…
- Conditions
- Spinal Cord Injuries, Rehabilitation, Exercise Program
- Trial name
- NCT05878145
- Testing
- Structured rehabilitation exercise program
- Where
- South Korea
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Insomnia
A Randomized, Double Blind, Parallel Group, Placebo Controlled, Multicenter Outpatient Trial Of PD 0200390 In Adults With Primary Insomnia
To demonstrate efficacy and characterize the dose response relationship of PD 0200390 on subjective wake after sleep onset in subjects with primary insomnia.
- Trial name
- NCT00569972
- Testing
- PD 0200390
- Where
- 84 sites in United States, Canada
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- Pfizer
Women in Need of Long Acting Reversibel Cntraception With the Intrauterine Levonorgestrel Releasing System, Mirena
Pretreatment With Mifepristone Prior to Mirena Insertion
Hypothesis: Pretreatment with mifeprsitone prior to Mirena placement will induce amenorrhea and reduce bleeding irrregularities during the initial months of Mirena use.
- Trial name
- MiMi (NCT01931657)
- Testing
- Mifepristone prior to Mirena
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Sarcopenia
Effects of Power-velocity Muscle Characteristics During Ageing
The purpose of this project is to investigate the age-related differences in force-velocity muscle characteristics during isolated knee extensions variable in speed and load, during cyclic movements on a usual and recumbent bike…
- Trial name
- NCT02692612
- Where
- Belgium
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy Volunteer Study, Pain Management
A Phase 1 Study of CG001419 Administered Orally in Healthy Subjects
This is a dose finding study of CG001419, administered as a single dose, with or without food, and as multiple doses. CG001419 is being tested in healthy volunteers in this trial with the goal of eventually developing the drug…
- Trial name
- NCT06636500
- Testing
- CG001419
- Where
- Australia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cullgen Australia Pty Ltd
HIV Infections
A Study to Explore the Association Between Blood Pressure, HIV and Antiretroviral Therapy
The purpose of this study is to explore the association between blood pressure, HIV and/or its treatment in a cross sectional observational study.
- Trial name
- NCT00131807
- Testing
- Blood Pressure Measurement, Questionnaire
- Where
- United Kingdom
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Loss of Smell, Olfactory Disorder
Olfactory Performance in Culinary Arts Students
The COVID-19 pandemic brought impaired smell and taste to the forefront of international public awareness and clinical importance.
- Trial name
- NCT06066307
- Testing
- Olfactory training
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Leigh Sowerby
Breast Cancer
A Evaluation of 3D Functional MIRA System in Women With Mammographically Dense Breasts
The purpose of this image acquisition study is to compare, in a Reader Study, the RI8 system used in conjunction with a conventional mammography to mammography alone, and to determine whether the addition of supplementary RI8…
- Trial name
- NCT03288792
- Testing
- RI8 device imaging
- Where
- 5 sites in United States
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Real Imaging Ltd.
Hemiplegic Cerebral Palsy
Comparison of Constraint Induced Movement Therapy and Mirror Therapy
Hemiplegia in infants and children is a type of Cerebral Palsy that results from damage to the part (hemisphere) of the brain that controls muscle movements. This damage may occur before, during or shortly after birth.
- Trial name
- NCT06294444
- Testing
- Constraint Induced Movement Therapy, Mirror therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
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