Clinical trials: Drug Distribution
Acute Respiratory Failure
Physiological Effects of a New Interface on Lung Ventilation and Gas Distribution
Hypoxemic Acute Respiratory Failure (hARF) is a common reason of admission to Intensive Care. Different modalities can be used to administer oxygen, which is the first supportive treatment in these patients.
- Trial name
- NCT04619641
- Testing
- High Flow Nasal Cannula (HFNC), Continuous Positive Airway Pressure (CPAP)
- Volunteers
- 15 people
- Sponsor
- University Magna Graecia
Healthy Participants
A Study to Learn How the Medicine Called [14C] PF-06821497 is Taken up Into and Removed From the Body.
The purpose of this study is to learn how a certain amount of [14C] PF-06821497 is taken up into the bloodstream and removed from the body. The study is seeking participants who are: Males aged 18 years or older.
- Trial name
- NCT06392230
- Testing
- Oral [14C] PF-06821497, Oral PF-06821497, IV [14C] PF-06821497
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pfizer
Multiple Myeloma, Hematologic Diseases
Multiple Myeloma Prognostic Indices
The aim of this study was to evaluate the impact of albumin / fibrinogen ratio, blood viscosity and RDW on the prognosis of a newly diagnosed MM patients
- Trial name
- NCT06095752
- Testing
- blood viscosity , albumin / fibrinogen ratio and red cell distribution
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Assiut University
Chemotherapy-induced Nausea and Vomiting
Comparative Effect Study Between Distal-proximal Point Association and Local Distribution Point Association in Chemotherapy-induced Nausea and Vomiting
The purpose of this study is to clarify whether distal-proximal point association is more effective than partial match point association by electro-acupuncture in the management of chemotherapy-induced nausea and vomiting .
- Trial name
- NCT02478047
- Testing
- only antiemetic (Ramosetron, Tropisetron and dexamethasone), Matching points ST36+CV12 plus antiemetic drug, Matching points PC6+CV12 plus antiemetic drug
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Tianjin University of Traditional Chinese Medicine
HIV
Combination Partner HIV Testing Strategies for HIV-positive and HIV-negative Pregnant Women
The overall objective of this study is to evaluate whether the addition of secondary distribution HIV self-test kits to existing partner notification guidelines increases the proportion of male partners who access facility-based…
- Trial name
- MP3 Pilot (NCT04124536)
- Testing
- HIV self-testing with partner notification.
- Where
- Zambia
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Ovarian Cancer
Regional Distribution Mapping of Lymph Node Metastasis in Epithelial Ovarian Cancer
The goal of this observational study is to investigate the metastatic pathways of lymph node involvement in ovarian cancer patients.
- Trial name
- NCT06853730
- Volunteers
- 654 people
- Sponsor
- Xu Huishan
Type 2 Diabetes
Abdominal Adipose Tissue Distribution in Type 2 Diabetic Patients Treated During 6 Months With Pioglitazone or Insulin
In type 2 diabetic patients with poor glycemic control despite maximum "classic" oral treatment, bed time insulin therapy may lead to a parallel increase in abdominal visceral and subcutaneous fat, whereas pioglitazone treatment…
- Trial name
- NCT00159211
- Testing
- UMULINE NPH, pioglitazone
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV/AIDS, HSV-2 Infection
The Impact of VCT and Condom Distribution as HIV Prevention Strategies Among Youth in Kenya
The vast majority of new HIV infections occur in sub-Saharan Africa, where nearly 2 million people become infected with HIV/AIDS every year.
- Trial name
- NCT03868644
- Testing
- Voluntary Counseling and Testing for HIV (VCT), Condoms
- Volunteers
- 10,646 people
- Sponsor
- Abdul Latif Jameel Poverty Action Lab
Nine Body Constitutions
The Distribution of Body Constitutions Among Hong Kong Elderly Population: A Cross-sectional Study
Hong Kong, similar as other developed economic entities, has been faced big challenges from increasing medical burden and aged population.
- Trial name
- NCT04776460
- Where
- China
- Volunteers
- 5,300 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Discopathy, Lumbago
Correlation Between RMI of Degenerative Disk Disease and Reduction of Pain After Disk-infiltration Treatments
The primary objective of the study is to demonstrate the difference in the reduction of pain at 1 month after intradiscal infiltration of corticosteroids depending on symmetrical or asymmetrical active discopathies with MRI…
- Trial name
- MODISC (NCT04142580)
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity & Overweight, Obesity (Disorder)
Weight Loss and Adipose Tissue Metabolism During Conservative Treatment of Obesity
This prospective observational study investigates weight loss and metabolic changes in adults with obesity undergoing standard clinical diet-induced lifestyle treatment and counseling.
- Trial name
- 4FAT (NCT07456124)
- Testing
- Diet-Induced Weight Loss Program
- Volunteers
- 22 people
- Sponsor
- University of Helsinki
Metastatic Prostate Cancer
Evaluate Safety, Whole-Body Distribution and Radiation Dosimetry in Metastatic Castration Resistant Prostate Cancer
A Study to Evaluate Safety, Whole-Body Distribution and Radiation Dosimetry of ZA-001, an Alpha-particle-emitting (At211) Radiopharmaceutical, in metastatic castration resistant prostate cancer
- Trial name
- NCT06359821
- Testing
- ZA-001
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Sichuan University
Drug Distribution
Statin Distribution
Anticipating an increased use of statins in children and adolescents, it is imperative that we understand the genetic and developmental characteristics affecting the pharmacokinetics and pharmacodynamics of statins in childhood…
- Trial name
- NCT02360826
- Testing
- Pravastatin, Simvastatin
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Microcytic Hypochromic Anemia
Red Cell Distribution Width Index Versus Red Cell Distribution Width as Discriminating Guide for Iron Deficiency Anaemia and Beta Thalassemia Trait .
Red Cell Distribution Width Index versus Red Cell Distribution Width as Discriminating Guide for Iron Deficiency Anaemia and Beta Thalassemia Trait .
- Trial name
- NCT03868306
- Testing
- CBC , Iron study and Haemoglobin electrophoresis .
- Volunteers
- 100 people
- Sponsor
- Assiut University