Clinical trials: Drug Eluting Stent
Coronary In-stent Restenosis
Restenosis Intrastent: Bioresorbable Vascular Scaffolds Treatment With Scoring Balloon Pre-dilatation (RIBS VI Scoring)
Treatment of patients with in-stent restenosis (ISR) remains a challenge. This study will assess the efficacy of Bioresorbable Vascular Scaffolds (BVS) (Abbott Vascular) in the treatment of patients suffering from ISR after…
- Trial name
- NCT03069066
- Testing
- Bioresorbable vascular scaffold. Absorb GT1 (Abbott)
- Where
- 10 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Spanish Society of Cardiology
Coronary Artery Disease, Ischemic Heart Disease
Cortisone or Drug Eluting Stents (DES) as Compared to Bare Metal Stents (BMS) to EliminAte Restenosis
The possibility of using the new drug eluting stents (DES) technology has significantly changed the mid-term outcome of percutaneous coronary interventions (PCI) in terms of reduced recurrence of angina.
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Atherosclerosis
- Trial name
- NCT00369356
- Testing
- Prednisone, Drug eluting coronary stent, Bare metal coronary stent
- Where
- 5 sites in Italy
- Volunteers
- 375 people
- Sponsor
- Universita di Verona
Coronary Stenosis, Coronary Artery Disease
Percutaneous Coronary Intervention (PCI) With Drug-Eluting Stents (DES) Versus Coronary Artery Bypass Graft (CABG) for Patients With Significant Left Main Stenosis
Recent technical advances in percutaneous coronary interventions have made it possible to approach patients with coronary lesions formerly considered to be classical candidates for bypass surgery, e.g.
- Trial name
- NCT00176397
- Testing
- Percutaneous coronary intervention (left main)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Leipzig
Coronary Artery Disease
ComparisiOn of Neointimal coVerage betwEen ZES and EES Using OCT at 3 Months
This study try to 1) evaluate the neointimal coverage and malapposition at 3 month after new zotarolimus eluting stent (Endeavor resolute) and everolimus eluting stent (Xience) implantation and 2) compare them between ZES…
- Trial name
- COVER OCT-II (NCT01091740)
- Testing
- ZES resolute (Endeavor Resolute), EES (Xience)
- Where
- 2 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Acute ST Segment Elevation Myocardial Infarction
Performance of Bioresorbable Scaffold in Primary Percutaneous Intervention of ST Elevation Myocardial Infarct
Patients presenting with acute ST elevation myocardial infarct urgently need revascularization. Standard of care is establishing bloodflow through the coronary vessels using thrombus aspiration catheter, and securing the result…
- Trial name
- BVS in STEMI (NCT02067091)
- Testing
- stent implant in a coronary artery
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 120 people
- Sponsor
- Haukeland University Hospital
Acute Myocardial Infarction
Everolimus Stent in Myocardial Infarction
Randomized trial to test the efficacy and safety of newer Drug Eluting Stent generation in patient with acute myocardial infarction treated with primary percutaneous coronary intervention (PCI)
- Trial name
- RaCES-MI (NCT01684982)
- Testing
- everolimus eluting stent, sirolimus eluting stent
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- San Giuseppe Moscati Hospital
Coronary De-novo Stenoses
Efficacy of the SeQuent®Please in the Treatment of De-novo Stenoses Versus Taxus™Liberté™
The aim of the trial is to assess the efficacy of the Paclitaxel-coated SeQuent®Please angioplasty balloon in the treatment of stenoses in native coronary arteries compared to a drug eluting stent.
- Trial name
- PEPCAD-DEBonly (NCT01084408)
- Testing
- SeQuent®Please (Paclitaxel coated balloon), Taxus™Liberté™ (Paclitaxel eluting stent)
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- University Hospital, Saarland
Restenosis
Treatment of Coronary In-Stent Restenosis
The purpose of this study is to compare efficacy of coronary in-stent restenosis therapy using drug eluting paclitaxel-coated balloon catheters with the latest generation of drug eluting stents releasing everolimus.
- Trial name
- TIS (NCT01735825)
- Testing
- paclitaxel-coated balloon catheter with Iopromide coating, drug eluting stent with everolimus, seal-wing paclitaxel-eluting balloon catheter
- Where
- Czechia
- Volunteers
- 199 people
- Sponsor
- University Hospital Ostrava
Drug-eluting Stent, Coronary Artery Disease
Efficacy of OSFIT Drug-Eluting Stent in Coronary Ostial Artery Stenosis
The purpose of this observational study is to evaluate the long-term effectiveness and safety of the OSFIT drug-eluting stent designed to facilitate procedures in coronary artery lesions.
- Trial name
- NCT06066450
- Testing
- Genoss® DES system, Genoss® Osfit system
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Genoss Co., Ltd.
Coronary Artery Disease, Coronary Restenosis
Clinical Performance of the Pantera Lux Balloon Versus the Orsiro Stent in Patients With In-stent Restenosis.
To determine in a randomized controlled trial (RCT) whether percutaneous coronary intervention - in patients with in-stent restenosis in either bare metal stents or drug eluting stents - with the Pantera Lux balloon is…
- Trial name
- BIOLUX-RCT (NCT01651390)
- Testing
- Percutaneous coronary intervention
- Where
- 14 sites in Germany, Latvia
- Volunteers
- 231 people
- Sponsor
- Biotronik AG
Coronary Artery Disease
Smart Angioplasty Research Team-Optimal Strategy for Side Branch Stenting in Coronary Bifurcation Lesion With Drug-Coated Balloon
A prospective, multi-center, open-label, randomized controlled, superiority trial. The aim of the study is to compare clinical outcomes between upfront 2-stenting strategy versus upfront drug-coated balloon (DCB)-based hybrid…
- Trial name
- SMART-DCB (NCT07019350)
- Testing
- Upfront DCB-based hybrid strategy, Upfront 2-stenting strategy
- Where
- 3 sites in South Korea
- Volunteers
- 520 people
- Sponsor
- Samsung Medical Center
ST-elevation Myocardial Infarction (STEMI)
Drug-Coated Balloon Versus Drug-Eluting Stent in Patient With ST-Segment Elevation Myocardial Infarction
Acute ST-segment elevation myocardial infarction (STEMI) is a life-threatening emergency requiring immediate intervention. The incidence of premature coronary artery disease (PCAD) is rising rapidly in China; its long-term…
- Trial name
- DCB-STEMI (NCT06742125)
- Testing
- Drug-coated balloon (DCB), Drug-eluting stent (DES)
- Where
- China
- Volunteers
- 1,244 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Peripheral Arterial Disease Below The Knee
Investigating the Safety and Clinical Performance of Seven iVascular Devices for Endovascular Intervention in the Popliteal and/or Infrapopliteal Arteries
The rationale of this study is to confirm and support the clinical safety and performance of the Oceanus 14pro, Oceanus 18 and Oceanus 35 Balloon Catheters, the Luminor 14m and Luminor 18 Drug Coated Balloons, the Angiolite BTK…
- Trial name
- POP-BTK (NCT05267548)
- Where
- 8 sites in Belgium
- Volunteers
- 143 people
- Sponsor
- iVascular S.L.U.
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
MIRAGE Study: Clinical Outcomes of the Mamba Sirolimus-Eluting PTCA Balloon
This Clinical Evaluation Report (CER) covers the Mamba Sirolimus-Eluting PTCA Balloon catheter intended for the treatment of coronary artery disease in de novo or in-stent restenosis lesions.
- Trial name
- NCT07326735
- Testing
- Mamba Sirolimus-Eluting PTCA Balloon, Percutaneous Coronary Angioplasty with Sirolimus-Coated Balloon
- Where
- 2 sites in Burma, Malaysia
- Volunteers
- 360 people
- Sponsor
- Frisch Medical Device Private Limited
Coronary Artery Disease
DES Versus BiOSS LIM - POLBOS II Study
Coronary bifurcation lesions pose therapeutic problems during percutaneous coronary interventions (PCI) and are associated with higher rates of periprocedural complications as well as higher rates of in-stent restenosis and stent…
- Trial name
- POLBOS II (NCT02198300)
- Testing
- Coronary angioplasty with stent implantation, Dual antipletlet therapy (DAPT)
- Where
- Poland
- Volunteers
- 202 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Coronary Artery Disease (CAD), Stenosis Coronary
Brazilian Prospective Registry of the Inspiron EVO Drug-Eluting Stent in Complex Coronary Lesions
The objective is to evaluate the efficacy and safety of the Inspiron™ EVO drug-eluting stent in complex coronary lesions in a real-world population.
- Conditions
- Coronary Artery Disease (CAD), Stenosis Coronary, Small Vessel Ischemic Disease, Multivessel Coronary Artery Disease
- Trial name
- PCI EVOlution (NCT07491107)
- Testing
- Inspiron EVO Drug-Eluting Stent
- Where
- Brazil
- Volunteers
- 2,000 people
- Sponsor
- Scitech Produtos Medicos SA
Coronary Artery Disease
Everolimus- Versus Biolimus-Eluting Stents in All-Comers
This study sought to investigate safety and efficacy of biolimus-eluting stents (BES) with biodegradable polymer as compared with everolimus-eluting stents (EES) with durable polymer through 3 years of follow-up.
- Trial name
- EverBio (NCT01472705)
- Where
- Switzerland
- Volunteers
- 814 people
- Sponsor
- University of Freiburg
Coronary Restenosis
Trial of a Novel Paclitaxel-coated Balloon With Citrate Excipient for Restenosis in -Limus Analogue DES
Hypothesis: Angioplasty with a novel paclitaxel-coated balloon (PCB; Agent, Boston Scientific) with citrate-based excipient will be non-inferior to conventional paclitaxel-coated balloon with iopromide excipient (PCB) for the…
- Trial name
- ISAR-DESIRE 3A (NCT02367495)
- Testing
- PCB
- Where
- Germany
- Volunteers
- 125 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Vascular Diseases
Drug Eluting Stent Zilver PTX vs Bare Metal Stent Zilver Flex
Randomized study comparing the results between drug-eluting stents and standard bare metal stents, when treating femoropopliteal lesions in patients with critical limb ischemia.
- Trial name
- NCT05296031
- Testing
- Treatment with Zilver PTX Drug Eluting Stent (DES) in femoropopliteal lesions, Treatment with Zilver Flex Bare Metal Stent (BMS) in femoropopliteal lesions
- Volunteers
- 49 people
- Sponsor
- Skane University Hospital
Myocardial Infarction
Efficacy of Everolimus-Eluting Versus Zotarolimus-Eluting Sten for Coronary Lesions in Acute Myocardial Infarction
Most of the previous data regarding the efficacy of the everolimus-eluting stent (EES) was derived from studies comparing EES with bare metal stent (BMS) or EES with paclitaxel-eluting (PES).
- Trial name
- EVERZOTA (NCT01347554)
- Testing
- Everolimus eluting stent, Zotarolimus eluting stent
- Where
- South Korea
- Volunteers
- 461 people
- Sponsor
- Yonsei University