Clinical trials: Drug Eluting Stents
Coronary Artery Disease
BIOFLOW III Satellite-ELADIS Orsiro Stent System
This registry is a clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT02029092
- Where
- 14 sites in Spain
- Volunteers
- 404 people
- Sponsor
- C.E.M. Biotronik, S.A.
Coronary Artery Disease, Myocardial Ischemia
Comparison of Biomatrix and Orsiro Drug Eluting Stent
The primary objective of the BIODEGRADE study is to evaluate clinical efficacy of the Orsiro drug-eluting stent compared with Biomatrix drug-eluting stent, both of which have biodegradable polymer for the treatment of all-comers'…
- Trial name
- BIODEGRADE (NCT02299011)
- Testing
- Orsiro drug eluting stent, Biomatrix drug eluting stent
- Where
- South Korea
- Volunteers
- 2,341 people
- Sponsor
- Seoul National University Bundang Hospital
Coronary Artery Disease, Coronary Occlusion
Safety and Efficacy of Drug-Coated Balloon Angioplasty for the Treatment of Chronic Total Occlusions
The purpose of this study is to investigate the safety and efficacy of drug-coated balloon angioplasty for the treatment of chronic total occlusions patients with chronic total occlusion (CTO) lesion.
- Conditions
- Coronary Artery Disease, Coronary Occlusion, Percutaneous Coronary Intervention, Chronic Total Occlusion of Coronary Artery
- Trial name
- NCT04744571
- Testing
- aspirin, betaloc, atorvastatin, rosuvastatin, clopidogrel, ticagrelor, coronary wires. or coronary balloons, drug-coated balloon
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Stenosis
Fractional Flow Reserve (FFR) Versus Intravascular Ultrasound (IVUS) in Intermediate Coronary Artery Disease
This study is a prospective, randomized, multi-center, open label trial to compare the clinical outcomes and effectiveness of Intravascular ultrasound (IVUS) versus Fractional Flow Reserve (FFR) guided Percutaneous coronary…
- Trial name
- FAVOR (NCT01175863)
- Testing
- Grey scale intravascular ultrasound (Galaxy or Virtual histology-Intravascular Ultrasound), Pressure wire(Radi Medical Systems)
- Where
- 8 sites in South Korea
- Volunteers
- 1,400 people
- Sponsor
- Ajou University School of Medicine
Coronary Arteriosclerosis
YUKON Choice Versus TAXUS Liberté in Diabetes Mellitus
Revascularisation procedures such as percutaneous coronary intervention are associated with overall worse outcomes in patients with diabetes mellitus.
- Trial name
- NCT00368953
- Testing
- Yukon Choice stent system, Taxus Liberté stent system
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- University of Leipzig
Coronary Bifurcation Lesion
Korean Coronary Bifurcation Stenting (COBIS) Registry III
The COBIS III registry is a multi-center, real-world registry of 2nd generation drug-eluting stenting in coronary bifurcation lesions in South Korea.
- Trial name
- COBIS III (NCT03068494)
- Where
- South Korea
- Volunteers
- 2,648 people
- Sponsor
- Samsung Medical Center
Peripheral Arterial Disease
PREVENT: Promus BTK
This is a single-arm, prospective, multi-center monitored trial recruiting patients with critical limb ischemia and with one or more lesions in the arteries below the knee.
- Trial name
- PREVENT (NCT01500070)
- Testing
- Everolimus-Eluting Stent (PROMUS ELEMENT)
- Where
- 8 sites in Belgium, Germany and 1 more
- Volunteers
- 70 people
- Sponsor
- Flanders Medical Research Program
Coronary Artery Disease
STOPping Versus Continuing Antiplatelet Therapy During Noncardiac Surgery and Procedures After Next Generation Drug-eluting Stent Implantation
Most previous trials support the absolute increase in bleeding risk with perioperative administration of antiplatelet. Furthermore, recent studies demonstrated that perioperative major bleeding may be related to increase…
- Trial name
- NCT03184805
- Testing
- Continuing aspirin, Stopping aspirin
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Yonsei University
Coronary Artery Disease
Everolimus- Versus Biolimus-Eluting Stents in All-Comers
This study sought to investigate safety and efficacy of biolimus-eluting stents (BES) with biodegradable polymer as compared with everolimus-eluting stents (EES) with durable polymer through 3 years of follow-up.
- Trial name
- EverBio (NCT01472705)
- Where
- Switzerland
- Volunteers
- 814 people
- Sponsor
- University of Freiburg
Coronary Disease
Web basEd soCial Media tecHnology to Improvement in Adherence to Dual anTiplatelet Therapy Following Drug-Eluting Stent Implantation
Few studies have attempt to improve DAPT adherence through social media. The investigators will explore the prevalence of DAPT discontinuation and prove the hypothesis that using social media will improve DAPT adherence among…
- Trial name
- WeChat (NCT03732066)
- Testing
- Usual Text Messages, Personalized Reminders, Interactive Responses
- Where
- China
- Volunteers
- 760 people
- Sponsor
- Guangdong Provincial People's Hospital
Stent Thrombosis, Coronary Artery Disease
CONNECT DES Registrty
To date, drug-eluting stents (DES) have become the standard of care in daily practice for the treatment of ischemic heart disease, by overcoming the risk of in-stent restenosis, a major issue raised in the bare-mare stents era.
- Conditions
- Stent Thrombosis, Coronary Artery Disease, Stent Stenosis, Myocardial Infarction
- Trial name
- NCT04715594
- Testing
- 1st-generation drug-eluting stent, 2nd-generation drug-eluting stents
- Where
- South Korea
- Volunteers
- 350,000 people
- Sponsor
- Yonsei University
Coronary Artery Disease, Coronary Artery Stenosis
Sirolimus-coated Balloon Versus Drug-eluting Stent in Native Coronary Vessels - TRANSFORM II
International, multicentric, prospective, investigator-driven, open-label, randomized (1:1) clinical trial to observe and evaluate the efficacy, of Magic Touch Sirolimus Coated Balloon (SCB) compared to one of the gold standard…
- Trial name
- TRANSFORM II (NCT04893291)
- Testing
- Everolimus Eluting Stent, Sirolimus Coated Balloon
- Where
- 53 sites in Bangladesh, Brazil and 9 more
- Volunteers
- 1,820 people
- Sponsor
- Fondazione Ricerca e Innovazione Cardiovascolare ETS
Coronary Restenosis
Compare the Efficacy and Safety of RESTORE DEB and SeQuent® Please in Chinese Patient With Coronary In-stent Restenosis
The purpose of this study is to evaluate the safety and efficacy of Paclitaxel drug eluting balloons (RESTORE DEB, 3μg/mm2 balloon surface area ) for success of intervention treatment and maintaining the vessels unobstructed in…
- Trial name
- NCT02944890
- Testing
- Drug Eluting Balloon Catheters(RESTORE DEB）, Drug Eluting Balloon Catheters(SeQuent® Please）
- Where
- 14 sites in China
- Volunteers
- 242 people
- Sponsor
- ZhuHai Cardionovum Medical Device Co., Ltd.
Coronary Artery Disease, Coronary Restenosis
The SCRIPPS DES REAL WORLD Registry
This study is a prospective, non-randomized, open-label registry of consecutive patients with CAD treated by stent-assisted PCI using at least one CypherTM stent. Up to 1000 pts will be included in the registry.
- Conditions
- Coronary Artery Disease, Coronary Restenosis, Coronary Thrombosis
- Trial name
- NCT00714623
- Testing
- Sirolimus-Eluting Bx Velocity Coronary Stent (CypherTM Sirolimus-Eluting Stent)
- Where
- United States
- Volunteers
- 859 people
- Sponsor
- Paul S Teirstein, MD
Coronary Artery Disease
The E-SERIES Registry for Supralimus® Coronary Stent for the Treatment of Unselected Patients With Coronary Lesions
E-SERIES Registry evaluate the procedural and clinical outcomes of the Supralimus® SES in the treatment of unselected, high risk patients having coronary Artery blockage in the real world clinical practice.
- Trial name
- NCT01368627
- Testing
- Supralimus® Sirolimus-Eluting Coronary Stent
- Where
- 7 sites in Brazil
- Volunteers
- 1,274 people
- Sponsor
- Sahajanand Medical Technologies Limited
Coronary Artery Disease
FUNctional eFficacy of Hybrid coronAry REvascularization
The purpose of the study is to compare iFR-guided hybrid coronary revascularization (HCR) and traditional coronary artery bypass grafting (CABG) in terms of a functional efficacy of revascularization assessed by weighted average…
- Trial name
- FUNFARE (NCT04698460)
- Testing
- Hybrid coronary revascularization, Coronary artery bypass grafting
- Where
- Russia
- Volunteers
- 13 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Coronary Disease, Coronary Artery Disease
SPIRIT V: A Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System in the Treatment of Patients With de Novo Coronary Artery Lesions (Diabetic Sub-Study)
The purpose of this Clinical Evaluation is a continuation in the assessment of the performance of the XIENCE V® Everolimus Eluting Coronary Stent System (XIENCE V® EECSS) in the treatment of patients with de novo coronary artery…
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- NCT01171820
- Testing
- TAXUS® Liberté™, XIENCE V® EECSS
- Where
- 28 sites in Austria, France and 9 more
- Volunteers
- 324 people
- Sponsor
- Abbott Medical Devices
Critical Limb Ischemia
Drug Eluting Temporary Spur Stent System vs Percutaneous Balloon Angioplasty for the Treatment of Critical Limb Ischemia
The purpose of this trial is to evaluate the safety and efficacy of the Drug Eluting Temporary Spur Stent System compared to PTA.
- Trial name
- DEEPER RCT (NCT06122974)
- Testing
- Drug Eluting Temporary Spur Stent System, Percutaneous Transluminal Balloon Angioplasty
- Volunteers
- 518 people
- Sponsor
- ReFlow Medical, Inc.