Clinical trials: Drug Eluting Stents
Coronary Artery Disease, Diabetes
Comparison of Two New Generation Drug Eluting Stents in Patients With Diabetes (OCT-DES)
The aim of this study is a comparative evaluation of re-endothelailisation of the Integrity Resolute zotarolimus eluting stent (Medtronic) and of the Promus Element erolimus eluting stent (Boston Scientific), in patients with…
- Trial name
- OCT-DES (NCT02060357)
- Testing
- Optical coherence tomography
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Barts & The London NHS Trust
Ischemic Heart Disease, Stable Coronary Artery Disease
To Evaluate Safety and Efficacy of CGBIO Stent Compared to Biomatrix Flex Stent
to evaluate safety and efficacy of CGBIO stent(DES) compared to Biomatrix flex stent(DES)
- Conditions
- Ischemic Heart Disease, Stable Coronary Artery Disease, Stable Angina, Unstable Angina
- Trial name
- NCT03089450
- Testing
- CGBio stent, Biomatrix flex
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- CGBio Inc.
Coronary Artery Disease, Coronary Disease
Sirolimus-Eluting Stents for Chronic Total Coronary Occlusions
Primary intracoronary stent placement after successfully crossing chronic total occlusions (CTO) decreases the high restenosis rate at long-term follow-up compared with conventional balloon angioplasty.
- Conditions
- Coronary Artery Disease, Coronary Disease, Coronary Stenosis
- Trial name
- NCT00258596
- Testing
- sirolimus-eluting stent
- Where
- 2 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- R&D Cardiologie
Coronary Artery Disease
Genetics Study of In-stent Restenosis
The investigators hypothesized that genetic variants of G protein influence the development of restenosis and clinical outcome of patients receiving drug-eluting stents (DES).
- Trial name
- ISR (NCT01670396)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Zhongshan Hospital
Coronary Stenosis
Evaluation of a New Nanotechnology Based Drug-Eluting Stent for Opening of Narrowed Arteries of the Heart
Coronary artery disease (CAD) is the largest cause of death and disability in the world. Besides medicines, the principle treatment of this condition requires opening of the narrowed arteries, responsible for angina and other…
- Trial name
- NCT00428662
- Testing
- drug eluting nonpolymeric nanoporous stent
- Where
- India
- Volunteers
- 200 people
- Sponsor
- All India Institute of Medical Sciences
Coronary Artery Disease, Ischemic Heart Disease
Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Non ST Segment Elevation Myocardial Infarction
- Trial name
- ECLIPSE (NCT03108456)
- Testing
- Orbital Atherectomy, Balloon
- Where
- 104 sites in United States
- Volunteers
- 2,005 people
- Sponsor
- Abbott Medical Devices
Angioplasty, Coronary Artery Disease
Drug-coated Balloon Versus Drug-eluting Stent for de Novo Lesions in Large Coronary Arteries Guided by Optical Coherence Tomography
OCT allows precise evaluation of intimal injury after lesion preparation and may improve the acute results and long-term outcomes after paclitaxel drug-coated balloon angioplasty.
- Trial name
- NCT04664283
- Testing
- DCB for de Novo Lesions in Large Coronary Arteries Guided by Optical Coherence Tomography
- Where
- 2 sites in China
- Volunteers
- 254 people
- Sponsor
- Liu Bin
Angina, Coronary Occlusion
XIENCE PRIME Japan Post-Marketing Surveillance (PMS)
The objectives of the PMS are to observe the frequency, type, and degree of device deficiency to assure the safety of the new medical device (XIENCE PRIME) as well as to collect information on evaluation of the efficacy and…
- Conditions
- Angina, Coronary Occlusion, Coronary Artery Disease, Coronary Artery Stenosis
- Trial name
- NCT01721096
- Testing
- XIENCE PRIME - Long Length (LL), XIENCE PRIME - Core Size
- Where
- Japan
- Volunteers
- 536 people
- Sponsor
- Abbott Medical Devices
Angioplasty
Spot Drug-Eluting Stenting for Long Coronary Stenoses
Most doctors who use the new drug-eluting stents for the treatment of long coronary narrowings tend to cover the full length of the lesion with long or multiple stents.
- Trial name
- NCT00738556
- Testing
- Drug-eluting stents (Cypher and Taxus)
- Where
- 2 sites in Greece
- Volunteers
- 179 people
- Sponsor
- Cardiovascular Research Society, Greece
Coronary Artery Disease
Comparative Clinical Study of Drug-coating Balloon Strategy and Drug-eluting Stent Strategy
The trial aims to evaluate the long-term clinical outcome of the DCB-only technique is non-inferior to the provisional T stenting with DES in the patients who have 'true' bifurcation lesions.
- Trial name
- Kissing-DCB (NCT04842838)
- Testing
- paclitaxel DCB, DES
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking University Third Hospital
Coronary Artery Diseases
BIOFLOW III Satellite-Italy Orsiro Stent System
Clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES). 500 subjects will be enrolled in this registry.
- Trial name
- NCT02028728
- Where
- 18 sites in Italy
- Volunteers
- 609 people
- Sponsor
- Biotronik Italia S.p.A.
Coronary Artery Disease
Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-III (LONG-DES-III)
This randomized study is a multi-center, randomized, study to compare the efficacy of sirolimus versus everolimus-eluting stent implantation for long coronary lesions.
- Trial name
- LONG-DES-III (NCT01078038)
- Testing
- Cypher, Xience V
- Where
- 20 sites in South Korea
- Volunteers
- 451 people
- Sponsor
- Seung-Jung Park
Coronary Artery Disease
Optical Frequency Domain Imaging (OFDI) Assessed Strut Coverage of New Terumo DES
Purpose of this study is to evaluate, after implantation of a drug eluting stent (DES), coverage of the stent struts by new tissue.
- Trial name
- DISCOVERY123 (NCT01844843)
- Testing
- TCD-10023 drug eluting stent
- Where
- 6 sites in France, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Terumo Europe N.V.
Coronary Artery Disease, Coronary Restenosis
Clinical Performance of the Pantera Lux Balloon Versus the Orsiro Stent in Patients With In-stent Restenosis.
To determine in a randomized controlled trial (RCT) whether percutaneous coronary intervention - in patients with in-stent restenosis in either bare metal stents or drug eluting stents - with the Pantera Lux balloon is…
- Trial name
- BIOLUX-RCT (NCT01651390)
- Testing
- Percutaneous coronary intervention
- Where
- 14 sites in Germany, Latvia
- Volunteers
- 231 people
- Sponsor
- Biotronik AG
Coronary Restenosis
Treatment of In-Stent Restenosis by Paclitaxel Coated PTCA Balloons (PACCOCATH - ISR I)
The PACCOCATH ISR study is a randomized, double-blinded German multicenter trial on the efficacy and tolerance of a paclitaxel coated balloon catheter in coronary in-stent restenosis.
- Trial name
- NCT00106587
- Testing
- PTCA, paclitaxel coated balloon catheter (device with drug)
- Where
- 5 sites in Germany
- Volunteers
- 52 people
- Sponsor
- University Hospital, Saarland
Ischaemic Heart Disease
Sirolimus Eluting Stents in Complex Coronary Lesions (SCANDSTENT)
The purpose of this study is to evaluate the clinical and angiographic outcome of implantation of stents eluting or not eluting Sirolimus in patients with complex coronary artery lesions suitable for percutaneous coronary…
- Trial name
- NCT00151658
- Testing
- Coronary Drug Eluting Stents for PCI
- Where
- Denmark
- Volunteers
- 322 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Stent Thrombosis
Long-Term Safety of Drug Eluting Stents in the "Real World" (FReIburger STent Registry)
The FReIburger STent Registry (FRIST) is designed to determine the long term safety and efficacy of Drug Eluting Stents (DES) in a "real-world" patient population requiring stent implantation.
- Trial name
- FRIST (NCT00905008)
- Testing
- transluminal percutaneous coronary intervention, Drug-Eluting and Bare-Metal stents
- Volunteers
- 1,502 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Intracranial Arteriosclerosis, Stenosis Artery
A Registry Study of Intracranial Atherosclerotic Stenosis Treatment by Intracranial Drug-eluting Stenting in China
The primary objective of this trial is to evaluate the long-term safety and efficacy of the NOVA intracranial drug-eluting stent system in "real world" patients with intracranial atherosclerotic stenosis.
- Conditions
- Intracranial Arteriosclerosis, Stenosis Artery, Drug-Eluting Stents, Intracranial Artery Stenosis
- Trial name
- NCT05692882
- Testing
- Drug-Eluting Stents
- Where
- 5 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Sino Medical Sciences Technology Inc.
Coronary Artery Disease
Evaluation of Effectiveness and Safety of XIENCE PRIME Stent (IRIS-PRIME)
The objective of this study is to evaluate effectiveness and safety of XIENCE PRIME stent in the "real world" daily practice as compared with other drug eluting stents (DESs)
- Trial name
- NCT01348399
- Where
- 29 sites in South Korea
- Volunteers
- 2,000 people
- Sponsor
- Seung-Jung Park
Coronary Artery Bypass Grafting
Treatment of Moderate Vein Graft Lesions With Paclitaxel Drug Eluting Stents: The VELETI Trial
HYPOTHESIS 1. Sealing moderate SVG lesions with the TAXUS stent prevents SVG atherosclerosis progression as evaluated by IVUS. 2.
- Trial name
- VELETI (NCT00289835)
- Testing
- Paclitaxel eluting stent
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- Laval University