Clinical trials: Drug Removal
Epilepsy, PET / MR
Multimodal PET Imaging With 18F-FDG/SV2A/TSPO for Resection Planning in Drug-Resistant Epilepsy
This study focuses on the application value of 18F-FDG, SV2A, and TSPO PET imaging in the preoperative localization of epileptogenic foci in epilepsy.
- Conditions
- Epilepsy, PET / MR, Synaptic Vesicle Proteins, Microglial Activation
- Trial name
- NCT07147309
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Weibing Miao, PhD
Accidental Hypothermia, Emergencies
Effect of Wet Clothing Removal Compared to Use of a Vapor Barrier in Accidental Hypothermia
The optimal method of prehospital insulation and rewarming of hypothermic patients have been subject of debate, and there is a substantial lack og high-quality evidence to guide providers.
- Trial name
- NCT05996757
- Testing
- Wet clothing removal
- Where
- Norway
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Non Small Cell Lung Cancer, Lung Cancer
Phase II Lung Metcore - Preoperative Metformin for Lung Cancer
This is a phase II single centre open label single arm pre-operative window of metformin treatment in stage I-IIIa Non small cell lung cancer.
- Trial name
- Metcore (NCT03086733)
- Testing
- Metformin
- Where
- 2 sites in Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Impacted Wisdom Teeth
Efficacy Study of IV Ibuprofen vs IV Acetaminophen Post Surgical Extraction
This study will compare how effective a single dose of an intravenous (IV) ibuprofen is when compared to single dose of IV acetaminophen in reducing pain.
- Trial name
- Caldolor (NCT02133326)
- Testing
- Caldolor, Ofirmev
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Tufts University School of Dental Medicine
Tooth Whitening, Tooth Discoloration
Clinical Research Study to Evaluate Stain Removal and Whitening Improvement
The objective of this clinical research study is to evaluate the stain removal and whitening improvement of a toothpaste containing Vitamin C and 1100 ppm F as sodium fluoride as compared to a matching placebo toothpaste…
- Trial name
- NCT07870018
- Testing
- Vitamin C toothpaste
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Bacterial Viability of Necrotic Pulp With Asymptomatic Apical Periodontitis
Molecular Analysis of Intracanal Microbes After Chemomechanical Procedure and Root Canal Medication: A Randomized Controlled Trial
This study aimed to evaluate clinically the intracanal microbes at molecular level after using established root canal medicament Calcium hydroxide and potential root canal medicament Glycyrrhizin.and Decontamination Analysis of…
- Trial name
- NCT06291623
- Testing
- Glycyrrhizin
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cerumen Impaction of Both Ears
Evaluation of a Novel Product for the Removal of Impacted Human Cerumen (Earwax)
This is a prospective, open-labeled clinical trial. Subjects that qualify for enrollment and provide informed consent will be treated with a novel topical cerumen (earwax) removal product.
- Trial name
- NCT02829294
- Testing
- E002 - cerumen removal aid
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Dr. Joseph Griffin
Pancreas Neoplasm
Effects of Chewing Gum Against Postoperative Ileus
The purpose of this study is to determine whether the use of chewing gum effects postoperative ileus after pancreaticoduodenectomy
- Trial name
- NCT04768660
- Testing
- gum
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Assiut University
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT04042948
- Testing
- Tylenol
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Healthy
Non-invasive Sampling Method for Skin Test: Optimization of Sample Collection and Extraction
When absorbent hygiene products-such as panty liners, sanitary pads, incontinence products, or wound care items-are used over extended periods, they can sometimes have negative effects on the skin.
- Trial name
- SPECIMEN (NCT07117747)
- Testing
- Healthy volunteers
- Where
- Sweden
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Essity Hygiene and Health AB
Slippery Pulse
Visualization Engineering Platform for Pulse Diagnosis of Traditional Chinese Medicine-The Research of Similar Moiré Feature Analyzing Approach Based on Recurrent Neural Network to Process the Measured Slip Pulse Wave-Images With Chun, Guan and Chy
The diagnoses processes of Traditional Chinese Medicine (TCM) focus on the following four main types of diagnoses methods consisting of inspection, olfaction, inquiry, and palpation.
- Trial name
- NCT04661605
- Testing
- Recurrent Neural Network
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Anesthesia, Tooth Extraction
Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial Surgery
The purpose of this pilot study was to compare two commonly employed intravenous drug combinations; I) nitrous oxide, midazolam, fentanyl, and ketamine and II) the same combination with substitution of propofol for ketamine, for…
- Trial name
- NCT06867068
- Testing
- Midazolam Hydrochloride, Fentanyl, Ketamine
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Hypertension
Assessment of Anesthetic Efficacy and Hemodynamic Stability of Two LA Drugs for Hypertensive Patients
Pain control in dentistry is an important factor for reducing the fear and anxiety associated with dental procedures. For tooth extraction, it is mandatory to use resources to manage pain and discomfort such as adequate…
- Trial name
- NCT06927726
- Testing
- 4% Articaine HCL With 1:100,000 Epinephrine, 3% plain mepivacaine HCL
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
IUD Removal
Use of Ibuprofen to Prevent IUD Site Effects
This research will determine whether prophylactic use of ibuprofen can prevent common side effects of the copper intrauterine device (IUD) and prevent early removal of the device.
- Trial name
- NCT00243815
- Testing
- ibuprofen
- Where
- Chile
- Volunteers
- 2,019 people, healthy volunteers welcome
- Sponsor
- FHI 360
Anesthesia
Improving Information Extraction From EEG on Cerebral Anesthetic Drug Effects
This is an interventional, randomized controlled study in health volunteers that involves collecting data on raw EEG waves measuring various combinations of anesthetic drugs during standardized drug titration.
- Trial name
- NCT02043938
- Testing
- SedLine EEG sensor
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Preventing Postextraction Complication
Controlling Post-extraction Complications of Impacted Mandibular Third Molar
Impacted mandibular 3rd molar will be extracted in all patients, then patients will be divided, according to material placed in extraction socket into 3 groups: control, hyaluronic acid and honey.
- Trial name
- NCT04816253
- Testing
- Normal saline, Hyaluronic acid, Methylprednisolone
- Where
- Saudi Arabia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Local Anaesthetic Drug Adverse Reaction
Computer - Controlled Intraligamentary Local Anaesthesia In Extraction of Primary Molars
Background: Exodontia poses a psychological threat for children, increasing the need for profound local anesthesia to assure painless extraction and maintain child cooperation on the dental chair.
- Trial name
- NCT04739735
- Testing
- Dental Local Anaesthesia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Effects of the Elements
Effect of Removal of Double Antibiotic Paste on Post Operative Pain
Recruited patients with necrotic pulp after application of double antibiotic paste are assigned to group (XP Endo Finisher file) and group( Passive ultrasonic irrigation) and group (conventional syringe irrigation with side…
- Trial name
- NCT04327453
- Testing
- double antibiotic paste with XP-endo Finisher file, double antibiotic paste with Irrisafe Ultrasonic tip, double antibiotic paste with side vented needle
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Minia University
Wound Healing, Acute Skin Wounds
Study of LUT017 Gel to Improve Healing of Skin Wounds After Removal of Benign Lesions in Healthy Adults
This is a Phase 1 research study evaluating the safety and potential benefits of a topical gel called LUT017 in helping skin wounds heal after minor skin procedures.
- Trial name
- NCT07463378
- Testing
- LUT017,Topical BRAF inhibitor
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Antoni Ribas
Healing of Extraction Socket
The Impact of a Known Bioactive Agent on the Resolution of Alveolar Socket Preservation
The advent of endosseous implant restoration has driven an increasing need for alveolar bone preservation and/or augmentation strategies.
- Trial name
- NCT02802436
- Testing
- Extraction with socket graft
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston University