Clinical trials: Drug Use
Drug Use, Hepatitis C
Evaluation of the Use of the GenXpert to Detect Hepatitis C RNA
The results of the GX device are equivalent to standard venous blood sampling. With this study we are going to determine the prevalence in drug users with difficult venous access.
- Trial name
- NCT04717856
- Testing
- screening: HCV RNA test and risk factors questionaire
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Poverty, Low-Income Population
Discount Generic Prescription Study
The goal of this study is to learn about the factors that influence people to take part in discount generic prescription programs.
- Trial name
- NCT00971022
- Testing
- Survey, Focus Group
- Where
- 3 sites in United States
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Tobacco Use Disorder
To Assess the Bioequivalence of the 4mg Prototype Mini Nicotine Lozenge to the Reference Product (Nicorette) in Healthy Smokers
This study will assess the bioequivalence of the test product (Nicotine Prototype Mini lozenge 4 milligrams [mg]) to a commercial reference product (nicotine polacrilex mini lozenge 4mg) in healthy smokers under fasting…
- Trial name
- NCT03543137
- Testing
- Nicotine Prototype Mini lozenge, Nicorette Mini Lozenge
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tobacco Use Cessation, Cancer Prevention
Project Impact 2: A Culturally Tailored Smoking Cessation Intervention for Latino Smokers
The goal of this research study is to learn how 3 different kinds of counseling treatments may help individuals to quit smoking.
- Trial name
- NCT02596711
- Testing
- Nicotine Patch, Questionnaires, Carbon Monoxide (CO) Test
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Fundic Gland Polyps
Fundic Gland Polyps and Proton Pump Inhibitor (PPI) Drugs
The class of proton pump inhibitor (PPI) medications such as omeprazole has proven extremely effective in the treatment and prevention of gastric and duodenal ulcers.
- Trial name
- NCT01130363
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Columbia University
Patients Hospitalised in Geriatrics
E-vone® Use Detect Falls Among hOspitalized Patients in geRiAtric Medicine
This study evaluates the usability of a new remote warning system for fall in old people. This system is integrated in a shoe. Patients hospitalized in a geriatric ward but also their informal and professional caregivers will…
- Trial name
- EDORA (NCT04067193)
- Testing
- usability survey
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Agitated; State, Acute Reaction to Stress, Agitation,Psychomotor
Mindful Melody: Feasibility of Implementing Music Listening on an Inpatient Psychiatric Unit and Its Relation to the Use of As Needed Medications for Acute Agitation
In this quality improvement project, our objectives were to assess the feasibility and effectiveness of using music as an adjunct to or replacement of pharmacological interventions for patient agitation on an inpatient…
- Trial name
- NCT04514432
- Testing
- Music
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Emergency Medicine, Frontline Providers
N95 Reuse During COVID-19
During critical personal protective equipment (PPE) shortages, such as those associated with the COVID-19 pandemic, Centers for Disease Control (CDC) recommends N95 extended use (wearing the same N95 for multiple patient…
- Conditions
- Emergency Medicine, Frontline Providers, Healthcare Worker
- Trial name
- ReuseN95 (NCT05148793)
- Where
- United States
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Latent Tuberculosis, Human Immunodeficiency Virus
Doravirine, Rifapentine and Isoniazid Interaction
Drug therapy for persons living with human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) co-infected with latent tuberculosis infection (LTBI) is complex.
- Conditions
- Latent Tuberculosis, Human Immunodeficiency Virus, Rifamycins Causing Adverse Effects in Therapeutic Use, Drug Interaction Potentiation
- Trial name
- DORIIS (NCT03886701)
- Testing
- Doravirine (DOR), Rifapentine (RPT), Isoniazid (INH)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Walter K. Kraft
Opioid Use Disorder, Opioid Use Disorders
Systems Analysis and Improvement to Optimize Opioid Use Disorder Care Quality and Continuity for Patients Exiting Jail
This study evaluates the effectiveness of a health systems strategy (the Systems Analysis and Improvement Approach - SAIA) that packages systems engineering tools (including cascade analysis, flow mapping, and continuous quality…
- Trial name
- SAIA-MOUD (NCT06593353)
- Testing
- Systems Analysis and Improvement Approach (SAIA)
- Where
- United States
- Volunteers
- 4,186 people, healthy volunteers welcome
- Sponsor
- University of Washington
Performance Enhancing Product Use
Effect of Creatine and Caffeine on Muscle Performance
To determine if creatine and caffeine can be co-supplemented without inhibiting the effects of creatine.
- Trial name
- NCT04290819
- Testing
- Creatine Monohydrate, Creatine Monohydrate and Caffeine, Caffeine
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Regina
Carbetocin, Oxytocic Drugs Causing Adverse Effects in Therapeutic Use
Comparison Of The Effects Of Carbetocin And Oxytocin In C-Sectıon
Obstetric hemorrhage is the most common cause of maternal mortality worldwide and its incidence is estimated to be approximately 24%.
- Trial name
- NCT05742854
- Testing
- C-sections operations, Oxytocin, Carbetocin
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ege University
Alcohol Use Disorder (AUD), Alcoholism
Assessing Habitual, Goal-Directed, and Pavlovian Influences in Alcohol Use Disorder
The first aim of this study is to establish the role of maladaptive reliance on habits for impaired control in addiction, employing a novel task - the Action-Sequence-Task (AST), which assesses interference between habitual and…
- Conditions
- Alcohol Use Disorder (AUD), Alcoholism, Substance Use Disorders
- Trial name
- ReCoDe (NCT06701500)
- Testing
- Pavlovian-to-instrumental transfer (PIT) paradigm, Action Sequence Task (AST), Basic psychological assessment (interview)
- Where
- Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Healthy Non-dependent, Recreational Sedative Users
Abuse Potential of Oral Gabapentin in Healthy, Non-Drug-Dependent Individuals With Recreational Sedative Drug Use Experience
The purpose of the present study is to assess prospectively the abuse potential of gabapentin compared to placebo and alprazolam in healthy non-drug-dependent recreational sedative drug users under fasted condition.
- Trial name
- NCT07777965
- Testing
- Alprazolam (Xanax), Gabapentin (Neurontin® (Registered Trademark))
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Viatris Inc.
Drug Resistance, Multiple, Travel Medicine
The Effect of Hand Hygiene on Colonization Rates With Multidrug Resistant Enteric Pathogens in Travellers
Travelling to tropical and subtropical countries is a known risk factor for becoming colonized with extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae.
- Trial name
- NCT03306407
- Testing
- Improved hand hygiene
- Where
- 2 sites in Switzerland
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Christoph Hatz
Cannabis Use, Healthy
Reward and Drug Effects on Mood and Brain Response
The goal of the study is to better understand the neural mechanisms underlying the rewarding, reinforcing properties of delta-9-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, among healthy young adults.
- Trial name
- NCT04512365
- Testing
- THC
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Drug Use
E-learning to Improve the Quality of Drug Prescribing in Hospitalized Elderly Patients
This randomized controlled pragmatic study is aimed to set-up, assess and implement an integrated e-learning program of medical education in an hospital setting, focused on teaching and implementing CGA added to geriatric…
- Trial name
- NCT02339792
- Testing
- E-learning
- Volunteers
- 697 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Substance-related Disorders, Alcohol-Related Disorders
LaunchPad: Supporting Healthy Decisions and Preventing Drug Use After High School
LaunchPad is an online substance use prevention program for high school seniors. The program is designed to help seniors develop skills and make informed decisions as they transition from high school to young adulthood.
- Conditions
- Substance-related Disorders, Alcohol-Related Disorders, Tobacco Use Disorder, Marijuana Use
- Trial name
- NCT07655609
- Testing
- Introduction, Norms re: Protective Behavior Strategies (PBS), Life Skills
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Prevention Strategies, LLC
Tobacco Use, Drug Use
Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention
The study aims to develop tobacco modules to be included in an innovative mobile-health (mHealth) intervention (hereon referred to as S4E) and to determine the feasibility and preliminary efficacy of the updated version of S4E in…
- Conditions
- Tobacco Use, Drug Use, Adolescent Behavior, Alcohol Use
- Trial name
- NCT03855410
- Testing
- S4E, Attention-Matched Control Group
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Risk Behavior, Drug Use
Couples Health Project: Couples-based Intervention to Reduce Drug Use and HIV Transmission Risk
This project tests the feasibility, acceptability, and preliminary efficacy of the Couples Health Project (CHP). CHP is a brief (3-session) couples-based Motivational Interviewing intervention which addresses drug use and sexual…
- Conditions
- Risk Behavior, Drug Use, Sex, Anal
- Trial name
- CHP (NCT03386110)
- Testing
- Couples Health Project (CHP), Education
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York