Clinical trials: Drug Users
Opioid Overdose
A Single-Dose, Bioequivalence Study of FMXIN001 4 mg Microspheres Powder
A Single-Dose, Bioequivalence Study of FMXIN001 4 mg Microspheres Nasal Powder.
- Trial name
- NCT04713709
- Testing
- Nasus Pharma FMXIN001, Nasal Naloxone liquid spray
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nasus Pharma
HIV, HIV Infections
Behavioral Intervention to Reduce Sexual and Injection Risks Among Female Sex Workers Who Also Inject Drugs in Mexico
The investigators propose a highly efficient four-arm (factorial) trial to simultaneously test the efficacy of two behavioral interventions aimed at: increasing condom use in the context of ongoing drug use and decreasing needle…
- Trial name
- FSW-IDU (NCT00840658)
- Testing
- Interactive injection and sexual risk intervention, Interactive Sexual Risk Intervention, Interactive Injection Risk Intervention
- Where
- 2 sites in Mexico
- Volunteers
- 584 people, healthy volunteers welcome
- Sponsor
- Steffanie Strathdee
HIV, Hepatitis
A Network & Dyad HIV Prevention Intervention for IDU's - 1
The purpose of this study is to evaluate a peer-based HIV prevention intervention that targets active injection drug users and their drug and sex partners.
- Trial name
- NCT00218335
- Testing
- Intervention Condition, Control Condition
- Where
- United States
- Volunteers
- 1,024 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Alcohol-induced Disorders, Drug Users
SBIRT Implementation for Adolescents in Urban Federally Qualified Health Centers
The purpose of this study is to examine the implementation of two evidence-based intervention strategies of SBIRT (Generalist vs. Specialist) for adolescent alcohol, tobacco, other drug use, and HIV risk behaviors.
- Conditions
- Alcohol-induced Disorders, Drug Users, Tobacco Use Disorder
- Trial name
- ST@T (NCT01829308)
- Testing
- The brief interventions are delivered by behavioral health counselors (Specialist), The brief interventions are delivered by the primary care provider (Generalist)
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Friends Research Institute, Inc.
Healthy Recreational Drug Users
Study to Evaluate the Abuse Potential of ACT-541468 in Healthy Recreational Drug Users
This placebo- and active controlled study will investigate the abuse potential of ACT-541468 in healthy recreational drug users
- Trial name
- NCT03657355
- Testing
- ACT-541468, Suvorexant, Zolpidem
- Where
- 2 sites in United States, Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Morphinan Opioid Overdose
Randomized Trial of Intranasal Versus Intravenous Naloxone in Level of Consciousness in Suspected Opioid Overdose
The purpose of this study is to determine which route of administration is better for treatment of opioid overdosed patients
- Trial name
- NCT01293058
- Testing
- Intranasal naloxone, Intravenous
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Drug Overdose
Bioavailability of a New Formulation of Nasal Naloxone for Prehospital Use
Overdose with potential deadly outcome is a serious problem among opioid abusers, not least in Norway. The annual death toll from overdose is about 250, twice the annual death toll from traffic accidents.
- Trial name
- NCT02158117
- Testing
- nasal naloxone
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Drug Abuse, Medication
A Study of the Abuse Potential of Dronabinol in Recreational Cannabinoid Users
The primary objective of this study is to evaluate the abuse potential of dronabinol oral solution in recreational cannabinoid users.
- Trial name
- NCT02094599
- Testing
- Dronabinol 10 mg, Dronabinol 30 mg
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- INSYS Therapeutics Inc
Reproductive Behavior, Sexual Behavior
Reducing Teen Pregnancy in the Emergency Department
This study will determine the feasibility, acceptability, and potential efficacy of an emergency department-based pregnancy prevention intervention targeting sexually active adolescent female emergency department patients.
- Conditions
- Reproductive Behavior, Sexual Behavior, Adolescent Behavior, Contraception
- Trial name
- ERICA (NCT03866811)
- Testing
- Dr. Erica
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Columbia University
Substance Use Disorder (SUD)
Trauma-informed Intervention to Reduce Substance Use and to Support Community Transition
The overall aim of this study is to reduce overdose risk for criminal legal system (CLS) involved women during community re-entry through the adaptation and testing of an innovative, trauma-informed, relational intervention…
- Trial name
- TRUST (NCT06651528)
- Testing
- TAU + TRUST, TAU + TRUST + Re-entry Recovery Support, Treatment as Usual (TAU)
- Where
- 4 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Michele Staton
Substance Abuse, Risk Reduction
First Years Away From Home: Letting Go and Staying Connected
Alcohol abuse is the leading cause of death and serious injury among college students, and students also experience significant harms from other types of substance misuse and risk behaviors.
- Conditions
- Substance Abuse, Risk Reduction, RIsky Sexual Behavior
- Trial name
- FYAH:LGSC (NCT03227809)
- Testing
- Handbook condition, Handbook plus condition
- Where
- United States
- Volunteers
- 910 people, healthy volunteers welcome
- Sponsor
- Washington State University
Overdose
An Evaluation of a Social Network Intervention for Primary and Secondary Prevention of Opioid Overdoses
The purpose of this study is to pilot and implement a peer mentor intervention focused on overdose prevention and care. The intervention consists of 3 sessions.
- Trial name
- NCT04212364
- Testing
- Peer Education, Narcan Nasal Product
- Where
- United States
- Volunteers
- 614 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Opioid Overdose
Opioid Rapid Response System: Naloxone Training in Communities
The pervasive impact of the opioid epidemic has touched all layers of society for the past two decades, resulting in over 115 deaths daily and imposing annual costs of $78.5 billion.
- Trial name
- NCT06238128
- Testing
- Opioid Rapid Resonse System (ORRS) training, Non-active opioid overdose response training
- Where
- United States
- Volunteers
- 773 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
HIV, AIDS
HIV Prevention for Injecting Drug Users in Kazakhstan
The proposed study addresses a significant public health threat of HIV, HCV and other STIs among a very high risk population of active IDUs and their sexual partners in Kazakhstan a region that is experiencing one of the fastest…
- Trial name
- NCT01690442
- Testing
- Couples Based HIV/STI Risk Reduction Intervention (CHSR), Renaissance Wellness Promotion (WP)
- Where
- Kazakhstan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Columbia University
Nicotine Dependence
GABA (Gamma Amino Butyric Acid) Medication for Tobacco
The goal of this study is to examine the effects of a GABA (gamma amino butyric acid)-enhancing medication, pregabalin (300 mg/day), on smoking behavior, tobacco withdrawal and cigarette craving in smokers.
- Trial name
- NCT00644137
- Testing
- pregabalin, cigarettes
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yale University
Vitiligo, Depressive Episode
Mental Health Associations With Vitiligo
This cohort study is a large population-based study in the UK to determine the risks of comorbid mental health conditions (including depression, anxiety and other potential psychological complications of vitiligo) in adults with…
- Conditions
- Vitiligo, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04953338
- Testing
- Exposure of mental health condtion of interest
- Where
- United Kingdom
- Volunteers
- 36,104 people, healthy volunteers welcome
- Sponsor
- Momentum Data
HIV Infections
Surveillance and Medical Help for HIV-infected Intravenous Drug Users in and Out of Prison
It is difficult to detect the intestinal protozoal infections among the HIV-infected persons or travelers diarrhea by using the traditional microscopy or staining methods.
- Trial name
- NCT00739258
- Where
- Taiwan
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Healthy Volunteer
A Study of the Abuse Liability Potential of Cenobamate in Recreational Drug Users
This randomized, single-dose, placebo- and active-controlled, crossover study will evaluate the abuse liability potential of cenobamate in recreational drug users with sedative drug use experience.
- Trial name
- NCT03509285
- Testing
- Alprazolam, Cenobamate
- Where
- 2 sites in United States, Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- SK Life Science, Inc.
Drug Abuse Illicit
Method Comparison of Intelligent Fingerprinting Drug Screening System
Prospective, multi-site, open-label, single- or double-dose, randomized, multi-site performance evaluation of accuracy of the Intelligent Fingerprinting Drug Screening System in the hands of intended users: "operators" and…
- Trial name
- NCT07650136
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Intelligent Bio Solutions Inc.
Opioid Use, Opioid-Related Disorders
Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER)
Among people at risk of opioid overdose and receiving care in an academic emergency department, family practice, opioid substitution clinic or general inpatient units, does brief opioid overdose resuscitation training and…
- Conditions
- Opioid Use, Opioid-Related Disorders, Opioid Withdrawal, Opioid Overdose
- Trial name
- SOONER (NCT04740099)
- Testing
- SOONER Video & Kit, Standard of Care
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Unity Health Toronto