Clinical trials: Drug Users
Drug Misuse, Addiction
Construction of a Risk Screening Tool for New Psychoactive Substance Misuse Among Adolescents and Young Adults
The goal of this observational study is to construct a risk tool available for screening young adults and adolescents at high risk of drug misuse and provides a chance for early intervention to young adults and adolescents at…
- Trial name
- NCT06714578
- Testing
- Questionnaire and Physical Exam
- Where
- China
- Volunteers
- 1,035 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Alcohol-induced Disorders, Drug Users
SBIRT Implementation for Adolescents in Urban Federally Qualified Health Centers
The purpose of this study is to examine the implementation of two evidence-based intervention strategies of SBIRT (Generalist vs. Specialist) for adolescent alcohol, tobacco, other drug use, and HIV risk behaviors.
- Conditions
- Alcohol-induced Disorders, Drug Users, Tobacco Use Disorder
- Trial name
- ST@T (NCT01829308)
- Testing
- The brief interventions are delivered by behavioral health counselors (Specialist), The brief interventions are delivered by the primary care provider (Generalist)
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Friends Research Institute, Inc.
Bronchoscope Users
Reusable Flexible Bronchoscopes Versus Single Use Bronchoscopes : a Satisfaction Survey
Reusable (RU) flexible bronchoscopes (FB) require intermediate level disinfection operations to prevent transmission of infectious agents from patient to patient.
- Trial name
- NCT03392610
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Limoges
Epilepsy, Contraception
Women With Epilepsy: a Pilot Study of PK and PD Anti-epileptic Drug Effects in Levonorgestrel Intrauterine System Users
The investigators will conduct a prospective, seven-month pilot study to explore pharmacokinetic (PK) and pharmacodynamic (PD) effects among women with epilepsy using the levonorgestrel intrauterine system (LNG IUS) for…
- Trial name
- WESAIL (NCT02362373)
- Testing
- levonorgestrel IUS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Columbia University
Medical Education, User-Computer Interface
The Effect of Virtual Simulation Training in Mastoidectomy
The purpose of this study is to investigate the effect of virtual simulation training on mastoidectomy dissection performance of otorhinolaryngology trainees, to explore performance assessment using a final-product analysis…
- Conditions
- Medical Education, User-Computer Interface, Clinical Skills, Motor Skills
- Trial name
- NCT02030873
- Testing
- Virtual simulation training
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Drug Abuse, Harm Reduction
Harm Reduction Intervention for Anabolic-androgenic Steroids Users: a Randomized Controlled Trial
This clinical trial aims to investigate the short and long-term efficacy of a harm reduction intervention in reducing the use of non-clinical anabolic-androgenic steroids (AAS) in abusive users of AAS.
- Conditions
- Drug Abuse, Harm Reduction, Minimization, Harm, Anabolic Steroids Adverse Events
- Trial name
- SOS-RCT-HR (NCT07039539)
- Testing
- harm reduction intervention in non-clinical anabolic-androgenic steroids users
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Quality of Life
Development of a Family Intervention to Address Drug Use and HIV in Vietnam
Vietnam is currently experiencing two epidemics -- injection drug use and HIV. HIV infection is rising rapidly, primarily among injecting drug users (IDUs).
- Trial name
- NCT01540188
- Testing
- Family Intervention to Address Drug Use and HIV in Vietnam
- Where
- Vietnam
- Volunteers
- 230 people
- Sponsor
- University of California, Los Angeles
Computer + Fluency, Computer Only
Evaluation of a Computerized Opioid Overdose Prevention Program
Unintentional fatal drug overdose (OD) is now the 2nd leading cause of accidental death in the general population. Fatal OD from opioid analgesics specifically has increased over 400% between 1999 and 2008, and nonfatal overdose…
- Conditions
- Computer + Fluency, Computer Only, Treatment as Usual
- Trial name
- NCT02040077
- Testing
- Computer + Fluency, Computer Only, Treatment as Usual
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Johns Hopkins University
Substance Use Disorder (SUD)
Trauma-informed Intervention to Reduce Substance Use and to Support Community Transition
The overall aim of this study is to reduce overdose risk for criminal legal system (CLS) involved women during community re-entry through the adaptation and testing of an innovative, trauma-informed, relational intervention…
- Trial name
- TRUST (NCT06651528)
- Testing
- TAU + TRUST, TAU + TRUST + Re-entry Recovery Support, Treatment as Usual (TAU)
- Where
- 4 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Michele Staton
Cocaine-Related Disorders, Substance-Related Disorders
Pharmacotherapy for Schizophrenic Drug Users - 6
The purpose of this study is to evaluate maintenance neuroleptics for Schizophrenic patients who are cocaine abusers.
- Conditions
- Cocaine-Related Disorders, Substance-Related Disorders, Shcizophrenia
- Trial name
- NCT00000281
- Testing
- Amantadine
- Where
- United States
- Sponsor
- Yale University
Opioid-Related Disorders
Buprenorphine Group Medical Visits in Primary Care
The primary goal of this research is to improve the effectiveness of buprenorphine maintenance treatment (BMT) within primary care.
- Trial name
- G-BMT (NCT02526212)
- Testing
- G-BMT, Treatment as usual, Buprenorphine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Montefiore Medical Center
Risk Behavior, Medication Adherence
Secondary HIV Prevention and Adherence Among HIV-infected Drug Users
This study will test whether 3H+ (Holistic Health for HIV) is comparable to the original HHRP+ (Holistic Health Recovery Program) in reducing HIV risk behaviors and improving ART (Antiretroviral Therapy) adherence in a randomized…
- Conditions
- Risk Behavior, Medication Adherence, HIV
- Trial name
- NCT01741311
- Testing
- 3H+ (Holistic Health for HIV), HHRP+ (Holistic Health Recovery Program)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Connecticut
Drug Overdose, Opioid-Related Disorders
Development of an Algorithm That Predicts Hypoventilation Due to an Opioid Overdose
RTM Vital Signs, LLC is developing a miniature wearable tracheal sound sensor that communicates with a cell phone containing a machine-learning diagnostic algorithm designed to detect and predict the onset of mild, moderate, and…
- Trial name
- NCT03845699
- Testing
- Diagnostic algorithms that detects/predicts hypoventilation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RTM Vital Signs, LLC
Drug Abuse
A Study to Evaluate Abuse Potential of Istradefylline
This study is to evaluate the abuse potential of single-doses of istradefylline compared to placebo and phentermine in recreational stimulant users.
- Trial name
- NCT02609477
- Testing
- Istradefylline, Phentermine 45 mg
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kyowa Kirin Co., Ltd.
Infusion Safety, Medication Safety
Air-in-Line Alarms During Antineoplastic Drug Infusion
The goal of this observational study is to evaluate infusion alarms, particularly air-in-line alarms, during antineoplastic drug infusion in oncology care settings.
- Conditions
- Infusion Safety, Medication Safety, Antineoplastic Drug Administration, Air-in-Line Alarm
- Trial name
- AIR-ONC (NCT07718711)
- Testing
- Routine Infusion Technologies
- Where
- 5 sites in Italy
- Volunteers
- 40 people
- Sponsor
- Associazione Italiana Infermieri di Area Oncologica
Abuse Potential
Study Evaluating Abuse Potential of Lyrica® in Healthy Non-Drug Dependent Recreational Opioid Users
This is a Phase 4 clinical study in healthy non-drug dependent recreational opioid users to assess the abuse potential of Lyrica when taken alone or in combination with oxycodone.
- Trial name
- NCT05053126
- Testing
- Pregabalin 300mg, pregabalin 450 mg, Pregabalin 300 mg with oxycodone 20 mg
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Viatris Specialty LLC
HEPATITIS C, Virus, Human Immunodeficiency
Antiviral Pharmacology and Adherence in Drug Users
Approximately one half of all Americans living with Hepatitis C virus (HCV) are drug users, yet they are the least likely to receive HCV treatment.
- Trial name
- NCT02573376
- Testing
- Directly Observed Therapy, Wirelessly Observed Therapy
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Colorado, Denver
HIV Infections, Hepatitis C
Behavioral Intervention for HIV and HCV-Uninfected Injection Drug Users
The purpose of this study is to test whether a six-session behavioral intervention for HIV and HCV seronegative injection drug users is effective in reducing sexual and injection risk behaviors that could lead to primary HIV and…
- Trial name
- NCT00164372
- Testing
- Peer Education Intervention
- Where
- 5 sites in United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV Testing, Intention
HST for Female Sex Workers/Drug Users in Kazakhstan
The goal of this behavioral intervention clinical trial is to assess acceptability, feasibility, and preliminary efficacy of a 4-session intervention to increase consistent HIV testing and linkage to care and prevention among HIV…
- Trial name
- AEGIDA (NCT06150937)
- Testing
- AEGIDA intervention arm, AEGIDA control arm
- Where
- Kazakhstan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- City University of New York
HIV
Computer-Assisted HIV Prevention for Young Drug Users
In this study, the investigators are developing and evaluating an interactive, computer-assisted HIV, STD and disease prevention program for young substance abusers that incorporates effective components of both prevention…
- Trial name
- NCT00182585
- Testing
- computer-based HIV, STD & Hepatitis Education, educator-delivered HIV, STD and Hepatitis education
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- National Development and Research Institutes, Inc.