Clinical trials: Drug Utilization Review
Medication Adherence
Patient-Centered Pharmacist Care in the Hemodialysis Unit: A Quasi-Experimental Interrupted Time Series Study
Nonadherence to medications by patients requiring hemodialysis (HD) leads to unfavorable clinical outcomes.Limited data exist on the influence of pharmacists on pharmacoadherence by patients requiring HD.
- Trial name
- NCT03576404
- Testing
- Patient-Centered Pharmacist Care
- Volunteers
- 72 people
- Sponsor
- King Abdullah International Medical Research Center
Multimorbidity, Polypharmacy
Optimizing PharmacoTherapy In the Multimorbid Elderly in Primary CAre: the OPTICA Trial
The objective of this randomized controlled trial (RCT) is to evaluate whether the Systematic Tool to Reduce Inappropriate Prescribing (STRIP), put into practice through the STRIP Assistant (STRIPA) and implemented by general…
- Trial name
- OPTICA (NCT03724539)
- Testing
- STRIPA intervention
- Where
- Switzerland
- Volunteers
- 323 people
- Sponsor
- University of Bern
Multiple Sclerosis
Medication Understanding in MS
The goal of this observational study is to learn how people with multiple sclerosis (MS) understand, organise, and use their medicines at home.
- Trial name
- MUMS (NCT07518381)
- Volunteers
- 80 people
- Sponsor
- University of Nottingham
Epidemiologic Factors
Patient Characteristics in Daily Radiological Practice of Gadovist® Application (PATRON)
To evaluate patient characteristics in the current daily radiological practice of Gadovist application. Special focus will be laid on the individual risk factors of patients, the indications for and the dose of Gadovist…
- Trial name
- NCT00874640
- Testing
- Gadobutrol (Gadovist, BAY86-4875)
- Where
- Germany
- Volunteers
- 3,711 people
- Sponsor
- Bayer
Overactive Bladder
Combined Anticholinergic Medication and Sacral Neuromodulation to Treat Refractory Overactive Bladder
This study is a retrospective chart review including all patients who received surgical placement of a SNM device with Dr. Noblett from 2001 to the present.
- Trial name
- NCT01047046
- Testing
- Retrospective chart review
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of California, Irvine
Ciprofloxacin Adverse Reaction
Ciprofloxacin Utilization and Adverse Events Occurrence in Community Pharmacy Setting
Background: Ciprofloxacin is a fluoroquinolone that is commonly used to treat a variety of diseases. Ciprofloxacin resistance is rising, resulting in suboptimal patient care.
- Trial name
- NCT05916105
- Testing
- Ciprofloxacin Tablets
- Where
- Egypt
- Volunteers
- 151 people
- Sponsor
- Damanhour University
Prescribing Patterns, Physician, Physician's Practice Patterns
Optimizing Proton Pump Inhibitors (PPI) Prescribing With EHR-Based Decision Support
The proposed study is a quality improvement initiative designed to rigorously evaluate new variations of UCLA Health's proton pump inhibitor (PPI) order panels, building on internal quality improvement efforts to optimize…
- Conditions
- Prescribing Patterns, Physician, Physician's Practice Patterns, Drug Utilization Review
- Trial name
- NCT06998966
- Testing
- Algorithmic Defaulting (Indication-Based Default), Active Physician Choice
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- University of California, Los Angeles
Drug Utilization Review
Medication Reviews in Elderly in Primary Care
The study is a follow-up of a randomized controlled study performed in 2011-2012 with medication reviews in elderly patients in Sweden. Additional data about mortality and hospital admissions have been collected.
- Trial name
- NCT04040855
- Testing
- Medication review
- Volunteers
- 369 people
- Sponsor
- Region Skane
Cognitive Symptom, Depression
Psychotropic Drug Use in the Elderly Living in Nursing Homes and the Influence of a Structured Drug Review
The overall aim of this study is to explore if a structured drug review will change clinical symptoms and the psychotropic drugs prescription rate in the elderly living in nursing homes (participants of the study).
- Conditions
- Cognitive Symptom, Depression, Anxiety, Neuropsychiatric Syndrome
- Trial name
- NCT03736577
- Testing
- Drug reviews with NorGeP-NH
- Where
- Norway
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Cardiovascular Diseases, Medication Adherence
Pharmacist-led Medication Review With Follow-up on Primary Care Cardiovascular Older Adult Patients.
Hypothesis: Medication Review with follow-up can improve clinical, health related quality of life and economic outcomes. To prove this hypothesis a cluster randomized controlled trial will be held in primary care centres of the…
- Conditions
- Cardiovascular Diseases, Medication Adherence, Drug Use, Hypertension
- Trial name
- POLARIS (NCT03502109)
- Testing
- Medication review with follow-up
- Where
- Chile
- Volunteers
- 340 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Diabetic Macular Edema
Chart Review: Drug Utilization Study in Participants Who Received Ozurdex™ (Dexamethasone Intravitreal Implant) 0.7 mg Injections for Visual Impairment Due to Diabetic Macular Edema (DME)
A retrospective, non-interventional, observational, multi-center, drug utilization study to be conducted in adult participants with visual impairment due to DME treated with Ozurdex implants in Germany and Switzerland from 1…
- Trial name
- NCT03889444
- Testing
- Dexamethasone intravitreal implant
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Allergan
Aging
Impact of Medication Review by Community Pharmacists
The aging population size has been enlarging globally. A higher number of older adults means a higher number of medication use. It is estimated that older adults are the largest medication consumers.That would result in various…
- Trial name
- NCT05297461
- Testing
- Medication review
- Where
- Malaysia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Monash University Malaysia
Adherence, Medication
Concordance : a New Concept for Clinical Pharmacy in Partnership With Patients at a Geriatric Day Clinic
The goal of this clinical trial is to assess the impact of pharmaceutical consultations in older patients having a comprehensive geriatric assessment at geriatric day-clinic.
- Trial name
- COPAPI-G (NCT06059235)
- Testing
- pharmaceutical care
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
HIV
Male Engagement in PMTCT Services
The study employs a quasi-experimental design in 8 public health centers in southwest Uganda offering care and treatment (C\&T) services.
- Trial name
- NCT01903889
- Testing
- clinic based intervention, clinic and community based intervention
- Where
- 7 sites in Uganda
- Volunteers
- 3,806 people, healthy volunteers welcome
- Sponsor
- FHI 360
Asthma
Randomised Controlled Trial of a Multi-faceted Community-based Intervention to Improve Asthma in Children
The objectives of this trials are to demonstrate, in children with poorly controlled asthma, that an intervention to increase the awareness and the impact of poor asthma control among parents and physicians of affected children…
- Trial name
- NCT00238888
- Testing
- asthma control awareness, Usual care
- Where
- Canada
- Volunteers
- 298 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cytomegalovirus (CMV), Kidney Disease
A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation
The main aim of this study is to assess the safety of maribavir in adults with severe CKD or comorbid ESRD including participants on artificial filtering of the kidney (dialysis) or the blood (hemodialysis).
- Conditions
- Cytomegalovirus (CMV), Kidney Disease, Kidney Failure
- Trial name
- NCT06243731
- Testing
- No Intervention
- Where
- 25 sites in Belgium, Estonia and 5 more
- Volunteers
- 10 people
- Sponsor
- Takeda
Acute Pain, Atrophic
Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy
The purpose of this study is to examine deficits in activation and motor patterns, as well as central drive in patients with rotator cuff tendinopathy.
- Conditions
- Acute Pain, Atrophic, Goals, Impairment
- Trial name
- NCT02971072
- Testing
- Subacromial injection, Physical Therapy
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Healthy
Effect of Pharmacist Initiated Recommendations On Prescribing For Participants In the Senior MEDS Personalized Medication Review
What are the demographic and medication utilization characteristics of participants in the Senior MEDS personalized medication review compared to other community-dwelling elderly, what is the level of satisfaction with Senior…
- Trial name
- NCT00205140
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cytomegalovirus (CMV)
A Study of Maribavir in Adults With Post-transplant Cytomegalovirus (CMV) Infection
The main aim of this study is to check how effective the treatment with Maribavir has been to remove the CMV viruses from the blood of an adult person with CMV infection after a transplant.
- Trial name
- NCT06615921
- Testing
- No Intervention
- Where
- 45 sites in Austria, Denmark and 8 more
- Volunteers
- 265 people
- Sponsor
- Takeda
Medication Compliance, Drug-Related Side Effects and Adverse Reactions
Improving Drug Safety in Emergency Patients -a Randomized Controlled Trial
Aim/Objective: Investigate the effect of implementing a working model for performing medication reconciliation (MR) and medication review (MRe) in the emergency department (ED), on readmissions, patient safety and efficiency of…
- Conditions
- Medication Compliance, Drug-Related Side Effects and Adverse Reactions, Remission, Medicinal Substance; Adverse Effect
- Trial name
- EPIMERR (NCT03123640)
- Testing
- Medication reconciliation and medication review
- Where
- Norway
- Volunteers
- 806 people
- Sponsor
- Diakonhjemmet Hospital