Clinical trials: Drug Withdrawal Headache
Migraine, Hemicrania
Home Detox in Medication Overuse Headache (MOH) During Covid-19 Emergency
Medication Overuse Headache (MOH) is a disabling condition that affects the 2% of migraine population. Medication overuse (MO) makes this condition very difficult to treat.
- Trial name
- MOHC (NCT04410536)
- Testing
- Symptomatic drugs, Bridge therapy, Mindfulness program
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Medication Overuse Headache, Analgesic Overuse Headache
Frovatriptan as a Transitional Therapy in Medication Overuse Headache
This study will analyze the effectiveness of a medication called Frovatriptan, in the context of medication overuse headache (MOH). MOH is a headache that develops when pain-killers are taken frequently.
- Trial name
- NCT01044251
- Testing
- Frovatriptan
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of Calgary
Medication Overuse Headache
Orbitofrontal Cortex (OFC) Influence on Addictive Medication Overuse Headache (MOH) Deriving From Migraine
Medication Overuse Headache (MOH) is an illness affecting about 1,5 % of the general population. It is characterized by chronic headache occurring for at least 15 days a month, by a use of antimigraine drugs during at least 3…
- Trial name
- MOH-PET (NCT00833209)
- Testing
- PET (withdrawal), Imaging
- Where
- 2 sites in France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Drug Withdrawal Headache
Postoperative Headache in Elective Surgery Patients
To evaluate the association of anaesthesia and surgery with postoperative headache in elective surgery patients By multiple logistic regression analysis of data collected during a six-month period from 446 patients undergoing…
- Trial name
- NCT02374346
- Volunteers
- 494 people
- Sponsor
- Attikon Hospital
Headache
Medication-overuse Headache (MOH): Withdrawal or Use of Preventative Medications Directly?
It is a common belief that patients with MOH rarely respond of preventative medications whilst overusing acute medications. However, no randomized trial has been done previously to prove such statement.
- Trial name
- NCT00159588
- Testing
- Betablockers or other preventive drugs based on primary headache type
- Where
- Norway
- Volunteers
- 64 people
- Sponsor
- Norwegian University of Science and Technology
Analgesic Rebound Headache
Detoxification and Treatment of Subjects With Medication Overuse Headache
The purpose of this study is to assess the benefits of almotriptan used as a transitional therapy and topiramate in subjects with medication overuse headaches (MOH.
- Trial name
- NCT00432549
- Testing
- Almotriptan, Topiramate
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The New England Center for Headache, P.C.
Endocrine Disorder, Deficiency
Endocrinological Profile in Patients With Medication-overuse Headache Before and After Withdrawal Therapy
The project will be conducted to investigate the hormonal homeostasis in men and women, with a special emphasis on sex hormones in men and AMH level in women, before and after withdrawal of the overused analgesics among MOH…
- Conditions
- Endocrine Disorder, Deficiency, Medication Overuse Headache, Migraine
- Trial name
- ENDOMOH (NCT04090333)
- Testing
- Standard withdrawal therapy
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Danish Headache Center
Headache
Prednisolone in the Treatment of Withdrawal Headache in Probable Medication Overuse Headache
The purpose of this study is to determine whether prednisolone is more effective than placebo in the first six days after initiation of medication withdrawal therapy for a medication overuse headache.
- Trial name
- NCT00135122
- Testing
- prednisolone
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sorlandet Hospital HF
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Chronic Migraine, Medication Overuse Headache
Mindfulness Therapy for Chronic Migraine
The aim is to assess the efficacy of adding on a Mindfulness-based therapy to pharmacological prophylaxis (experimental group: pharmacological prophylaxis + Mindfulness) against pharmacological prophylaxis only (control group) on…
- Trial name
- Mind-CM (NCT03671681)
- Testing
- Mindfulness, Prophylactic
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
HEADACHE
Efficacy Evaluation Of Great Occipital Nerve Electrical Stimulation On Rebound Headache
SENGO-CAM study is a sham-controlled simple blind trial which aim is to study the efficacy of great occipital nerve stimulation (GONS) associated with medication withdrawal in the treatment of medication overuse headache…
- Trial name
- NCT01184222
- Testing
- great occipital nerve stimulation
- Where
- 4 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice