Clinical trials: Drugs, Non-Prescription
Depression, Non-psychotic Diagnosis as Co-morbidity
The Canadian Armed Forces PEER Study
This is a prospective, single-blinded, randomized, multicenter study to evaluate the utility, safety, and efficacy of using PEER Interactive - an EEG-based technology - to inform the prescription of medications to participants…
- Trial name
- PEERCanada (NCT03625271)
- Testing
- The PEER Report
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- MYnd Analytics
Hyperoxaluria
Effect of Over-the-counter Dietary Supplements on Kidney Stone Risk
The purpose of this study is to ascertain whether certain supplements promote excessive urinary oxalate excretion and increase the risk for calcium oxalate kidney stones.
- Trial name
- NCT02404701
- Testing
- Aloe vera with cactus, Cranberry, Green tea extract
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Substance Use, Severe Mental Disorder
Validation of the Dutch Translation of the Tobacco, Alcohol, Prescription Medication and Other Substances (TAPS)-Tool
The aim of the study is to investigate the reliability and validity of the Dutch version of the TAPS-tool. This will be investigated in 2 groups: patients without intellectual disabilities treated in Flexible Assertive Community…
- Conditions
- Substance Use, Severe Mental Disorder, Intellectual Disability, Mild
- Trial name
- NCT05273021
- Testing
- TAPS
- Where
- 3 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Birgit Seelen-de Lang
Liver Failure
Understanding Patient's Knowledge and Use of Acetaminophen
Introduction to Study Objectives: In a joint collaboration of the Centers for Education and Research on Therapeutics (CERTS) at The University of Pennsylvania and the M.D.
- Trial name
- NCT00823758
- Testing
- Focus Groups, Personal Interviews
- Where
- 4 sites in United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Contraception, Contraception Behavior
The Over The Counter Pill National Study
This is a prospective cohort study of individuals purchasing the oral contraceptive pill over the counter (OTC) in pharmacies in 32 US states. The comparison group is people receiving a prescription (Rx) for oral contraception.
- Conditions
- Contraception, Contraception Behavior, Contraceptive Usage, Health Care Utilization
- Trial name
- NCT05988983
- Testing
- Availability of OTC contraceptive pill
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Diabetic Foot Ulcer
Laser Therapy for At-Home Treatment of Diabetic Foot Ulcers - Canada
The global prevalence of diabetes is on the rise and with it increase in prevalence of diabetic foot ulcers (DFU). These recalcitrant wounds are difficult to manage and pose a heavy economic burden.
- Trial name
- LLL&DIAB-02 (NCT03687580)
- Testing
- B-Cure Laser Pro
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Scarborough Rouge Hospital
Healthy
Effects of Dietary Conditions on Drug Response
This non-treatment study will examine how different dietary conditions may affect a person's response to commonly used drugs.
- Trial name
- NCT04315961
- Testing
- Blinded drug dose conditions
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Liver Diseases
DILIN - Prospective Study
The purpose of this study is to identify individuals who have suffered a liver injury arising as an idiosyncratic reaction to a prescription drug or a complementary and alternative medicine.
- Trial name
- NCT00345930
- Where
- 6 sites in United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Duke University
SARS-CoV-2 Infection, Covid19
Over-the-counter Medications & COVID-19
Ibuprofen is one of several common medications implicated in coronavirus disease 2019 (COVID-19) severity. On March 11, the Lancet Respiratory Medicine published a letter stating ibuprofen can increase angiotensin-converting…
- Trial name
- OTC℞&COVID19 (NCT04500639)
- Where
- Canada
- Volunteers
- 461 people
- Sponsor
- University of Alberta
Adverse Events
Strategies for Improving Proton Pump Inhibitors (PPIs) Prescription Associated to Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Background Despite the low prevalence of serious complications associated with non-steroidal anti-inflammatory drugs (NSAIDs) use, there is a widespread use of gastroprotective proton pump inhibitors (PPIs) in order to prevent…
- Trial name
- NCT01128127
- Testing
- Group education, audit-feedback and computer support, Audit-feedback and computer support, Control
- Where
- Spain
- Sponsor
- Servicio Canario de Salud
Acne
The Comparative Efficacy of an Over the Counter Light Therapy Mask vs Over the Counter Topical Benzoyl Peroxide 2.5% and Used in Combination With Over the Counter Adapalene Gel 0.1% for Mild to Moderate Acne
This is a single-center prospective study of two standard-of-care treatments to evaluate the efficacy of the Neutrogena® Light Therapy Acne Mask an Over the Counter (OTC) Blue/Red light LED mask, as compared to the combination of…
- Trial name
- NCT03650881
- Testing
- Neutrogena ® Light Therapy Acne Mask (MASK), Topical OTC benzoyl peroxide 2.5% gel and OTC adapalene
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Atherosclerotic Heart Disease With Angina Nos
Clinical Study on Adjuvant Treatment of Coronary Heart Disease Angina Pectoris With Chinese Patent Medicine
A prospective cohort study was performed in patients with angina pectoris who were treated with oral Chinese patent medicine and Western medicine.Collect primary and secondary efficacy indicators such as the incidence of…
- Trial name
- CSCD-TCM (NCT04022031)
- Testing
- Chinese patent medicine
- Where
- China
- Volunteers
- 12,400 people
- Sponsor
- Tianjin University of Traditional Chinese Medicine
Atopic Dermatitis
Human Testing of an Over-the-Counter (OTC) Cream in Children With Eczema
This three week study will be conducted to determine the safety and efficacy of an over-the-counter (OTC) cream in children with mild to moderate atopic dermatitis.
- Trial name
- NCT01326910
- Testing
- Colloidal Oatmeal, Topical Cream
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Johnson & Johnson Consumer Products Company Division of Johnson & Johnson Consumer Companies, Inc.
SARS-CoV-2 Infection, Influenza A
Usability and Clinical Validation of the Flu A/B/COVID-19 + RSV Multiplex Rapid Test
This will be a prospective study for the clinical validation of the CorDx Tyfast Flu A/B/COVID-19 + RSV Multiplex Rapid Test for the qualitative detection and differentiation of SARS-CoV-2, Influenza A, Influenza B and RSV in AN…
- Conditions
- SARS-CoV-2 Infection, Influenza A, Influenza B, RSV
- Trial name
- CorDx 4in1 (NCT07875270)
- Testing
- Flu A/B/COVID-19 + RSV Multiplex Rapid Test
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- CorDx, Inc.
Dry Eye Disease (DED)
Randomized Single Center Study to Evaluate Tolerability, Symptoms, and Visual Functional Outcomes With the Use of OTC Lubricating Eye Drops in Subjects With Dry Eye Disease
A study to evaluate the effect of over- the- counter (OTC) lubricating eye drops on tolerability, symptoms and visual outcomes in patients with dry eye disease (DED)
- Trial name
- NCT07676084
- Testing
- Preservative Free Polyethylene glycol 400 0.25%, Propylene Glycol (0.6%), Carboxymethylcellulose sodium 0.5%, Glycerin 1.0%, Polysorbate 80 0.5%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Andover Research Eye Institute
Circumference Reduction
Study of Over-The-Counter Use of Low Level Laser Light Therapy for Body Contouring of the Waist, Hips and Thighs
The purpose of this study is to test the ability of the lay end user to understand the information contained in the User's Guide; to correctly identify patients who are suitably qualified to receive treatment; and to correctly…
- Trial name
- NCT02167867
- Testing
- Lay End Users, Treatment Subject Group
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation
Skin Health
The Effects of Over-the-Counter Products on the Skin
The primary purpose of this study is to investigate the safety and tolerability of commonly used over-the-counter products and the effects of the products on skin health.
- Trial name
- NCT03641430
- Testing
- Supportive care with OCT product
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Non-critical Emergency Room Patients Receiving Lortab Medication or Prescription During Their Emergency Room Visit
Video Assisted Informed Consent for Lortab to Improve Patient Satisfaction and Knowledge
In order to compare two different forms of patient education; patients who receive Lortab medication or prescription during their ED visit are randomized to receive either standard patient education (from healthcare provider) or…
- Trial name
- NCT01374295
- Testing
- video, standard education
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Albany Medical College
Acute Pain, Surgery
Prescribing Vs. Recommending Over-The-Counter (PROTECT) Analgesics for Patients with Postoperative Pain:
This is a research project in which two standard of care practices will be evaluated to examine the difference in outcomes. The goal is to improve patient care and safety.
- Trial name
- PROTECT (NCT05370404)
- Testing
- Prescription by surgical team, Recommendation by surgical team
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Michigan
Migraine Headache
Integrating Acupuncture Into the Management of Migraines
This research is being done to study the effect of incorporating acupuncture into the management of migraines. The primary aim is to determine in a randomized, controlled study whether individuals experiencing migraines have…
- Trial name
- NCT01481103
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National University of Health Sciences