Clinical trials: Dry Eye, completed
Dry Eye
Efficacy and Safety of Ocudox Lid Wipes Compared to Traditional Lid Cleaning
The use of povidone iodine solution for prophylaxis of endophthalmitis is well established for intraocular procedures like cataract surgery and for injections of anti-VEGF agents for retinal diseases such as age-related macular…
- Trial name
- NCT03763006
- Testing
- Eyelid cleaning
- Where
- Singapore
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Dry Eye Syndromes
A Clinical Trial to Evaluate the Safety and Efficacy of Rreproxalap in Adults With Dry Eye Disease
A Randomized, Double-Masked, Vehicle-Controlled Crossover Clinical Trial to Assess Efficacy and Safety of 0.25% Reproxalap Ophthalmic Solution Compared to Vehicle in Subjects with Dry Eye Disease
- Trial name
- NCT05424549
- Testing
- Reproxalap Ophthalmic Solution (0.25%), Vehicle Ophthalmic Solution
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Dry Eye, Dry Eye Disease (DED)
A Study in the Treatment of Mild to Moderate Dry Eye Disease Comparing Saline to TTAX03.
The purpose of this randomized, controlled, multicenter study is to evaluate the safety and efficacy of TTAX03 in participants with mild to moderate DED. The primary question it aims to answer is if TTAX03 is safe.
- Conditions
- Dry Eye, Dry Eye Disease (DED), Dry Eye Disease With Severe Keratitis
- Trial name
- NCT06780306
- Testing
- TTAX03
- Where
- 9 sites in United States
- Volunteers
- 74 people
- Sponsor
- BioTissue Holdings, Inc
Dry Eye, Meibomian Gland Dysfunction
IPL and MGX Versus MGX Alone in the Treatment of Dry Eye Disease Secondary to MGD
The aim of the current study is to examine the contribution of intense pulsed light (IPL) for relieving signs and symptoms of dry eye due to meibomian gland dysfunction.
- Trial name
- NCT03265652
- Testing
- Intense Pulsed Light (IPL) therapy
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Lumenis Be Ltd.
Uveitis, Conjunctivitis
Ocular Manifestations in Rheumatic Diseases
This is a search strategy for determining the prevalence of ocular complications in inflammatory rheumatic diseases for the purposes of a meta analysis.
- Conditions
- Uveitis, Conjunctivitis, Keratoconjunctivitis Sicca, Xerophthalmia
- Trial name
- NCT03753893
- Testing
- No intervention used
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Dry Eye
Evaluation of the Efficacy and Safety of DM934 Versus Théalose on Eye Dryness
This study is a multicentric, comparative, randomized, investigator-blinded, parallel group study to demonstrate the non-inferiority of DM934 in comparison with Théalose in terms of cornea and conjunctiva staining (Oxford score)…
- Trial name
- NCT06245421
- Testing
- DM934, Théalose
- Where
- 5 sites in France, Poland and 2 more
- Volunteers
- 85 people
- Sponsor
- Horus Pharma
Dry Eye Disease
Comparison of Efficacy Between 100% Platelet-rich Plasma and 100% Serum Eye Drops in Dry Eye Disease
Dry eye disease (DED) is a common eye problem, affecting 5% to 50% of the world population. Although the disease is not fatal, it substantially reduces quality of life and creates a high economic burden as high as over 50 billion…
- Trial name
- NCT04683796
- Testing
- 100% Autologous platelet rich plasma, 100% Autologous serum
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Mahidol University
Meibomian Gland Dysfunction
EyeBag Effectiveness in Meibomian Gland Dysfunction
Meibomian gland dysfunction (MGD) is a common condition that causes the secretion from meibomian glands in the eyelids to become blocked. Normally, the secretion helps to maintain a healthy tear film.
- Trial name
- MGD (NCT01870180)
- Testing
- EyeBag
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Aston University
Dry Eye, Contact Lens Complication
Treating Contact Lens Discomfort With Orthokeratology
The primary aim of this study is to understand if orthokeratology can be used to improve contact lens comfort and the secondary aim is understand patient adaptation to orthokeratology.
- Trial name
- NCT03566680
- Testing
- Orthokeratology
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Keratoconjunctivitis Sicca
Tolerability and Efficacy Study of Reinnerva/Lubristil+G vs Vismed
The clinical investigation #1122 is a Post Market Clinical Follow Up Study on the EC marked medical device Reinnerva/Lubristil +G, sterile eye drops, compared to Vismed medical device, sterile eye drops, to demonstrate the…
- Trial name
- NCT07422259
- Testing
- Reinnerva/Lubristil +G sterile eye drops (artificial tears), Vismed sterile eye drops (artificial tears)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Medivis SRL
Dry Eye Disease
Diurnal Variation in Tear Osmolarity
The purpose of this study is to measure the change in Tear Osmolarity during the course of the day to support clinical diagnosis of aqueous deficiency or meibomian gland disease and differentiate between the two forms of dry eye.
- Trial name
- NCT01321424
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ophthalmic Consultants of Long Island
Evaporative Dry Eye
Quality of Life Improvement in Dry Eye Patients After Intense Pulsed Light Therapy Compared to Punctal Plugs
Dry eye disease (DED) is a widely spread disorder of tears and ocular surface affecting hundreds of millions around the world. Manifestations resulting from moderate to severe DED have significant effects on the patient's quality…
- Trial name
- NCT05331924
- Testing
- IPL therapy, Punctal plugs
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Dry Eye, Contact Lens Complication
Dailies Total 1 Sphere Contact Lenses
CL discomfort is a complex phenomenon that has been defined by the Tear Film and Ocular Surface Society in their seminal report on contact lens (CL) discomfort as a condition that results in "episodic or persistent adverse ocular…
- Trial name
- NCT05239494
- Testing
- DT1 Sphere Contact Lenses
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Dry Eye
A Study to Assess the Efficacy and Safety of Tanfanercept (HL036) Ophthalmic Solution in Participants With Dry Eye
The objective of this study was to compare the safety and efficacy of tanfanercept ophthalmic solution 0.25% with placebo for the treatment of the signs and symptoms of dry eye.
- Trial name
- VELOS-3 (NCT05109702)
- Testing
- 0.25% Tanfanercept Ophthalmic Solution
- Where
- 10 sites in United States
- Volunteers
- 260 people
- Sponsor
- HanAll BioPharma Co., Ltd.
Contact Lens Complication, Dry Eye
Correlation Study of Corneal Nerve Changes and Dry Eye in Contact Lens Wearers
This study aims to analyze the changes of corneal nerve morphology and function in contact lens-related dry eye(CLADE) patients and further discuss the role of corneal nerve in the genesis and development of CLADE.
- Trial name
- NCT04663529
- Testing
- contact lens
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Dry Eye Disease (DED)
Photobiomodulation in Combination With Topical Cyclosporine A or Tacrolimus
The objective of the study is to evaluate the effectiveness of Low-level light therapy (LLLT) in combination with either topical Cyclosporine A (CsA) or topical Tacrolimus, using each non-steroidal immunosuppressant as an active…
- Trial name
- NCT07239128
- Testing
- Low-level light therapy (LLLT), Topical Cyclosporine A, Topical tacrolimus
- Where
- 2 sites in Italy
- Volunteers
- 160 people
- Sponsor
- University of Seville
Dry Eye Disease
Study of INV-102 Ophthalmic Solution in Adults With Moderate to Severe Dry Eye Disease
Phase 2 study to assess the efficacy of topically administered eyedrops of INV-102 during 4-week repeat dosing in subjects with moderate to severe dry eye disease.
- Trial name
- NCT06370039
- Testing
- INV-102, Vehicle
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Invirsa, Inc.
Dry Eye, Fibromyalgia
The Pathogenesis of Idiopathic Dry Eyes
Dry eyes are a very common complaint. In some patients, we can identify the reason for the dryness; however, in others the dryness has no clear cause. Dryness can lead to eye irritation, redness, and sometimes changes in vision.
- Trial name
- NCT01254201
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dry Eye Syndromes
Efficacy of T2259 in DED
The purpose of this study is to compare the performance and safety of T2259 versus Vismed Multi in dry eye patients with superficial keratitis.
- Trial name
- NCT03874429
- Testing
- T2259, Vismed multi
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Laboratoires Thea
Dry Eye
Performance and Safety Assessment of T2769 in Contact Lens Wearers With Dry Eye Symptoms.
This is a confirmatory clinical investigation. The objective is to collect new additional clinical data demonstrating the safety and performance of the device in the contact-lens wearing population with dry eyes.
- Trial name
- NCT05931861
- Testing
- T2769
- Where
- 6 sites in Bulgaria
- Volunteers
- 34 people
- Sponsor
- Laboratoires Thea
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.