Clinical trials: Dry Eye Disease (DED)
Periodontitis, Dry Eye Disease (DED)
Association Between Periodontitis and Dry Eye Disease: A Cross-Sectional Study
This study is aiming at exploring the association between periodontitis and dry eye disease, which are both chronic inflammatory diseases that might have common pathogenic mechanisms.
- Trial name
- NCT07873697
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sulaimani
Myopia, Dry Eye Disease (DED)
Study of Eye Fatigue From Digital Screens and Its Impact on Visual Performance in People With Normal Vision and Myopia, With and Without Dry Eye Symptoms and Signs
The goal of this observational study is to investigate the effects of eye fatigue induced by screen task on dry eye disease (DED) signs and symptoms, visual performance, and visual behavior in young adults with and without DED…
- Trial name
- RReye (NCT07844408)
- Testing
- Eye Exams, Ocular Biometry and Aberrometry, Wearing a Smartwatch
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Essilor International
Dry Eye Disease (DED), Meibomian Gland Dysfunction (Disorder)
Effect of Oral Isotretinoin on Ocular Surface and Meibomian Glands
The aim of the study was to evaluate meibomian gland morphology using non-contact meibography and ocular surface changes in patients with acne vulgaris treated with isotretinoin as indicators of dry eye, which is known to be a…
- Conditions
- Dry Eye Disease (DED), Meibomian Gland Dysfunction (Disorder), Acne Vulgaris
- Trial name
- NCT07753811
- Testing
- isotretinoin
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Fuchs Endothelial Corneal Dysfunction, Open Angle Glaucoma (OAG)
A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases
The overall goal of this study is to develop Brillouin microscope as a novel tool for measuring biomechanical and hydration properties of human tissues in vivo.
- Conditions
- Fuchs Endothelial Corneal Dysfunction, Open Angle Glaucoma (OAG), Dry Eye Disease (DED), Keratoconus
- Trial name
- NCT07780890
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Dry Eye Disease (DED), Glaucoma
Blinking Exercise Study
The goal of this clinical trial is to evaluate whether a structured blinking exercise can improve symptoms and signs of dry eye disease (DED) in adults with glaucoma who are using topical intraocular pressure-lowering…
- Trial name
- NCT07554937
- Testing
- Structured Blinking Exercise Training
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Dry Eye, Dry Eye Disease (DED)
Telemedicine for Evaluating Dry Eye Disease (DED) Using a Mobile Phone-Attached Portable Automatic Ocular Surface Imaging Device (PAOSID): A Patient-Operated Diagnostic and Continuous Ocular Surface Monitoring (COSM) System
Dry eye disease (DED) is a common eye condition that is becoming more widespread. Detecting it early, keeping track of its progression, and following up regularly can help protect vision and prevent serious complications.
- Trial name
- NCT07341724
- Testing
- Dr Eye
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Dry Eye Disease (DED)
Investigator Initiated Trial Using Dry Eye Surveys to Evaluate and Better Understand FDA Approved Acoltremon Treatment for Dry Eye Disease in Real World Treatment Settings (DESERT)
Dry eye disease (DED) is a common, chronic and multifactorial disease of the ocular surface presenting with signs and symptoms of ocular discomfort, visual disturbance and fluctuation, tear film instability, ocular surface…
- Trial name
- (DESERT) (NCT07281950)
- Testing
- acoltremon 0.003%
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Center for Sight Las Vegas
Dry Eye Disease (DED), Asthenopia
Effect of Smart Phone Reflective Light Film on Dry Eyes and Asthenopia
This study aimed to evaluate the effect of anti-reflection (AR) and circularly polarized (CP) film on video display terminal (VDT) induced dry eye and asthenopia after limited time and close distance of visual tasks under light…
- Trial name
- NCT06992635
- Testing
- using non-processing screens, using AR+CP screens
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Dry Eye Disease (DED)
Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery
To review how patients report using a hyaluronate crosslinked canalicular gel placed before cataract surgery
- Trial name
- LaReCa (NCT07155057)
- Testing
- Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Dry Eye Disease (DED)
A Study Evaluating the Efficacy and Safety of RCI001 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye
The objective of this study is to evaluate the safety and efficacy of 0.25% RCI001 Ophthalmic Solution twice a day (BID) and four times a day (QID) compared to placebo (vehicle) in the treatment of the signs and symptoms of dry…
- Trial name
- NCT07068958
- Testing
- 0.25% RCI001 Ophthalmic Solution
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- ORA, Inc.
Dry Eye Disease (DED)
Correlation of Dry Eye Disease, Problematic Smartphone Use and Sleep Quality in Adolescents and Young Adults
The goal of this observational study is to learn about the status quo and relationship of dry eye, problematic smartphone use, bedtime procrastination, and sleep in adolescents and young adults.
- Trial name
- NCT07020871
- Where
- China
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Dry Eye Disease (DED)
Vizol S DIGI EYE Efficacy and Safety Study in Patients With Dry Eye
The clinical investigation was intended to investigate the efficacy, ocular tolerability and safety of Vizol S DIGI EYE, a new eye drops, solution developed by JADRAN - GALENSKI LABORATORIJ d.d., in patients with moderate to…
- Trial name
- NCT07050446
- Testing
- Vizol S DIGI EYE eye drops, 0,9% saline solution, eye drops
- Where
- 3 sites in Serbia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Jadran Galenski laboratorij d.d.
Dry Eye Disease (DED), Cataract
Impact of DED on the Accuracy of Preoperative Keratometry Values in the Calculation of IOL Power for Cataract Surgery.
This study looks at how dry eye disease can affect important eye measurements needed before cataract surgery. These measurements guide us in choosing the right artificial lens to implant, which is essential for achieving clear…
- Trial name
- NCT06989827
- Testing
- Preservative free artificial tear
- Where
- Croatia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Sestre Milosrdnice
Dry Eye Disease (DED), Dry Eye
Role of Corneal Nerves in Dry Eye Disease
This study aims to determine whether corneal nerve function and morphology are affected by tear film instability and ocular surface homeostasis loss.
- Conditions
- Dry Eye Disease (DED), Dry Eye, Dry Eye Sensation, Corneal Nerve
- Trial name
- NCT06841471
- Where
- Switzerland
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Daniela Nosch
Dry Eye Disease (DED), Tear Break-Up Time
Efficacy of 0.28% Sodium Hyaluronate Eye Drops in Patient With Moderate to Severe Dry Eye
This study aimed to evaluate the efficacy and safety of 0.28% preservative-free SH and 0.18% SH eye drops in patients with dry eye disease.
- Conditions
- Dry Eye Disease (DED), Tear Break-Up Time, Tear Disorder, Tear Film Insufficiency
- Trial name
- NCT06860659
- Testing
- 0.28% Sodium Hyaluronate , preservative free eye drops, 0.18% Sodium Hyaluronate , preservative free eye drops
- Where
- Thailand
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand