Clinical trials: Dual Diagnosis
Dual Diagnosis, Substance Use Disorder
Psychosocial Factors in Dual Diagnosis in a General Hospital
Dual diagnosis, defined as the co-occurrence of a mental disorder and a substance use disorder, is frequently associated with increased clinical severity, functional impairment, and poorer health outcomes.
- Conditions
- Dual Diagnosis, Substance Use Disorder, Mental Disorders
- Trial name
- DUAL-HVP (NCT07443033)
- Where
- Spain
- Volunteers
- 125 people
- Sponsor
- Hospital Virgen del Puerto
Dual Diagnosis, Risk Youth
Virtual Reality (VR-GINSO) as an Complement to Intervention for Alcohol and Cannabis Use in Youth in Residential Care
The goal of this RCT is to evaluate the effects of a virtual reality intervention on self-efficacy regarding alcohol and cannabis use among at-risk youth in various residential mental health treatment centers who have…
- Conditions
- Dual Diagnosis, Risk Youth, Antisocial Behavior
- Trial name
- VR-GINSO (NCT07834606)
- Testing
- Virtual Reality, Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad Francisco de Vitoria
Opioid Use Disorder, Dual Diagnosis
Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness
Homelessness severely affects health and well-being and is particularly negative for youth. Between 70-95% of youth experiencing homelessness (YEH) report problem substance use and 66-89% have a mental health disorder.
- Conditions
- Opioid Use Disorder, Dual Diagnosis, Housing Problems, Mental Disorder in Adolescence
- Trial name
- NCT06311838
- Testing
- Motivational Interviewing/Community Reinforcement Approach (MI/CRA), Strengths-Based Outreach and Advocacy (SBOA ), Services as Usual (SAU)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Ohio State University
Dual Diagnosis, Alcohol Use Disorder
The 15-Mental Project: Implementation and Evaluation of the 15-Mental in a Mental Health Hospital Setting
The present project will implement and evaluate the effectiveness of a novel, but simple model for addressing and treating alcohol problems among patients admitted to outpatient treatment at mental health hospitals, called the…
- Conditions
- Dual Diagnosis, Alcohol Use Disorder, Hazardous Alcohol Use, Screening and Brief Intervention
- Trial name
- NCT07728968
- Testing
- 15-Mental.
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Alcoholism, Substance-related Disorders
CRP and S&A for Inpatient Veterans
The purpose of this study is to evaluate how well three types of treatments work to improve the outcomes for people with substance use problems.
- Conditions
- Alcoholism, Substance-related Disorders, Dual Diagnosis
- Trial name
- CRP and S&A (NCT05054738)
- Testing
- Combined Recovery Program, Stable & Able (S&A)
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- VA Office of Research and Development
Dual Diagnosis
Cannabidiol for Treatment of Non-affective Psychosis and Cannabis Use
This trial examines the efficacy of cannabidiol (CBD) versus risperidone for treatment of psychosis in patients with non affective-psychosis and lifetime use of cannabis.
- Trial name
- NCT04105231
- Testing
- Cannabidiol, Risperidone
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Lone Baandrup
Schizophrenia, Dual Diagnosis
Cannabis, Schizophrenia and Reward: Self-Medication and Agonist Treatment?
In this translational research proposal, based on our formulation, we seek to confirm and expand upon data obtained in our pilot study suggesting that cannabis and the cannabinoid agonist dronabinol, given in low dose to patients…
- Conditions
- Schizophrenia, Dual Diagnosis, Psychotic Disorder, Cannabis Use Disorder
- Trial name
- NCT01964404
- Testing
- Marijuana, Dronabinol
- Where
- 2 sites in United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Mental Disorder, Behavior Disorders
A Transdiagnostic Mentalization-based Intervention for Parents With Mental Disorders
The aim of this randomised clinical trial is to evaluate the short and longterm effects of a transdiagnostic mentalization-based intervention (Lighthouse MBT Parenting Program) compared to care as usal (CAU) for parents with a…
- Conditions
- Mental Disorder, Behavior Disorders, Diagnosis, Psychiatric, Diagnosis Dual
- Trial name
- LIGHTHOUSE (NCT06315114)
- Testing
- Lighthouse MBT Parenting Program (LPP), Care as usual (CAU)
- Where
- 2 sites in Denmark
- Volunteers
- 170 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Depression, Dual Diagnosis
A Randomized Double-Blind Controlled Trial of Creatine in Female Methamphetamine Users
Methamphetamine (MA) addiction is a public health concern that causes substantial harm to individual users, and imposes an economic burden in the U.S. totaling up to $48.3 billion annually.
- Conditions
- Depression, Dual Diagnosis, Drug Addiction
- Trial name
- NCT02192931
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Perry Renshaw
Dual Diagnosis, Psychosis
VR Based Therapy to Treat Anxiety in Dual Diagnosis
Dual diagnosis refers to patients with both severe mental illness and substance abuse. Dual diagnosis is therefore a challenging condition to treat, and the group typically represents the most vulnerable individuals in society.
- Conditions
- Dual Diagnosis, Psychosis, Agoraphobia, Social Anxiety Disorder
- Trial name
- NCT06315660
- Testing
- Cognitive Miljeu Therapy, Virtual Reality based CBT for Anxiety
- Volunteers
- 30 people
- Sponsor
- Mental Health Centre Sct. Hans
Osteoporosis, Diagnosis
Comparison of Detection Rates Between Two Commonly Used Bone Density Measurement Methods
72 adult patients who underwent lumbar spine anteroposterior DXA and QCT examinations at Qianfoshan Hospital in Shandong Province from January 2019 to December 2022 were selected, with an interval of no more than 3 months between…
- Conditions
- Osteoporosis, Diagnosis, Dual Energy X-ray Absorptiometry, Quantitative Computed Tomography
- Trial name
- NCT06299865
- Testing
- Ungrouped
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Xiaoqian Zhang
Alcoholism, Substance-related Disorders
Group Motivational Interviewing (GMI) For Homeless Veterans In VA Services
Homeless Veterans with substance use disorders (SUDs) are a major group served by VA and are heavily represented in VA housing. VA recently adopted a 'Housing First' approach emphasizing rapid housing placement to initiate…
- Conditions
- Alcoholism, Substance-related Disorders, Dual Diagnosis
- Trial name
- NCT02233738
- Testing
- Group Motivational Interviewing (GMI), Control Treatment Condition (CT)
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- VA Office of Research and Development
Diagnosis, Dual (Psychiatry)
Efficacy of Animal-assisted Therapy in Patients With Borderline Personality Disorder and Addictions.
Animal-assisted therapy (AAT) is a complementary intervention of therapy that has shown positive results in the treatment of various pathologies.
- Trial name
- NCT05115266
- Testing
- Animal-assisted therapy (AAT, Usual treatment
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Miguel Monfort Montolio
Diagnosis, Dual (Psychiatry)
Animal-Assisted Therapy in the Residential Treatment of Schizophrenia and Addictions
Animal-assisted therapy (AAT) is a complementary intervention of therapy that has shown positive results in the treatment of various pathologies.
- Trial name
- NCT05103865
- Testing
- Animal-assisted therapy (AAT), usual treatment
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Miguel Monfort Montolio
Bipolar Disorder, Alcohol Use Disorder
Ondansetron for Bipolar Disorder and Alcohol Use Disorders
The purpose of the study is to determine if ondansetron, as an add-on therapy, is associated with reduced depressive symptoms and alcohol use in outpatients with bipolar disorder (BPD), cyclothymic disorder, schizoaffective…
- Conditions
- Bipolar Disorder, Alcohol Use Disorder, Dual Diagnosis
- Trial name
- NCT02082678
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Texas Southwestern Medical Center
Trauma, Diagnosis Dual
Efficacy of Laser Doppler Flowmetry as a Diagnostic Tool in Assessing Revascularization of Traumatised Teeth
The aim of the study is to evaluate the efficacy of Laser Doppler flowmetry in determining the changes in the pulpal blood flow during the post-traumatic period of traumatised permanent teeth.
- Trial name
- NCT04967456
- Testing
- Measurement of pulpal blood flow of traumatised tooth
- Where
- 2 sites in Bulgaria
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Schizophrenia, Dual Diagnosis
Cannabis and Schizophrenia: Self-Medication and Agonist Treatment
The first aim of this study is to determine whether a brain reward center (BRC) deficiency in patients with schizophrenia (SCZ) and cannabis use disorder (CUD) will be normalized when patients are given cannabis or dronabinol.
- Conditions
- Schizophrenia, Dual Diagnosis, Schizoaffective Disorder, Psychotic Disorder
- Trial name
- NCT00946348
- Testing
- Dronabinol, Cannabis
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Diagnosis, Dual (Psychiatry)
Dual Integrated Attention Program (DAIP) in People With Severe Dual Diagnosis
Aim: validate a Dual Integrated Attention Program (D-AIP) for mental health nursing in people with Severe Dual Diagnosis admitted to a psychiatric hospitalization unit Design: Randomized Controlled Trial.
- Trial name
- PAI-D (NCT04442776)
- Testing
- D-AIP
- Volunteers
- 86 people
- Sponsor
- Cardenal Herrera University
Schizophrenia, Cannabis Abuse
Clozapine for Cannabis Use in Schizophrenia
Many individuals with schizophrenia also suffer from marijuana addiction that worsens their problems related to schizophrenia. Most of the medications prescribed for schizophrenia have no effect on reducing marijuana use.
- Conditions
- Schizophrenia, Cannabis Abuse, Cannabis Dependence, Dual Diagnosis
- Trial name
- CLOCS (NCT01639872)
- Testing
- Clozapine, Risperidone
- Where
- 9 sites in United States
- Volunteers
- 49 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Dual Diagnosis, Cocaine Abuse
Abstinence-Linked Money Management Multisite
Randomized clinical trial comparing a money management-based intervention involving storage and management of client funds, substance abuse counseling, and risk reduction counseling to individualized drug counseling.
- Conditions
- Dual Diagnosis, Cocaine Abuse, Cocaine Dependence, Polysubstance Abuse
- Trial name
- NCT01327586
- Testing
- ATM, Individual Drug Counseling
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- Yale University