Clinical trials: Dual-energy CT
Pulmonary Embolism
Optimization of DE-CTPA Images and Diagnostic Pathway: Using Low Concentration Iodine Contrast Material
The investigators aimed to compare the image quality and diagnostic performance of DECTPA using lower concentration iodine contrast materials and using normal concentration iodine contrast materials in the evaluation of suspected…
- Trial name
- NCT06212882
- Testing
- Lower concentration and lower volume contrast agent group
- Where
- China
- Volunteers
- 2,100 people
- Sponsor
- Wuxi People's Hospital
Nasopharyngeal Carcinoma
Screening Effect of Dual-energy CT Combined With Nasopharyngeal Endoscopy for Screening Nasopharyngeal Carcinoma
All participants will be tested for EBV-related biomarkers, including EBNA1-IgA, VCA-IgA, and BNLF2b total antibody (P85-Ab), and participants with high serologic risk will be selected based on serologic test results, and…
- Trial name
- NCT05884983
- Testing
- participants will undergo dual-energy CT and endoscopy
- Where
- China
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan People's Hospital, Guangdong, China
Aortic Aneurysm
Dual Energy CT Urography With Reduced Iodinated Contrast
The goal of this study is to validate that Dual Energy CT (DECT) urography when performed with a 50% reduction in iodinated contrast dose results in a CT exam with equal or better image quality and equal or better diagnostic…
- Trial name
- NCT02283307
- Testing
- Reduced contrast DECT scan, Standard contrast SECT scan
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Washington
Osteoporosis, Diagnosis
Comparison of Detection Rates Between Two Commonly Used Bone Density Measurement Methods
72 adult patients who underwent lumbar spine anteroposterior DXA and QCT examinations at Qianfoshan Hospital in Shandong Province from January 2019 to December 2022 were selected, with an interval of no more than 3 months between…
- Conditions
- Osteoporosis, Diagnosis, Dual Energy X-ray Absorptiometry, Quantitative Computed Tomography
- Trial name
- NCT06299865
- Testing
- Ungrouped
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Xiaoqian Zhang
Dental Diseases
Dual Energy Cone-Beam Computed Tomography (DE-CBCT) Assessment of Jaw Bone Density
Current radiologic imaging modalities used in dentistry provide information on the morphology of the hard tissues. Additional information on the density of bone has practical relevance, for example, in dental implant treatment…
- Trial name
- NCT04686084
- Testing
- Dual-energy computed tomography scan
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Los Angeles
Dual Energy CT (DECT), Prostate Cancer
Applications of Dual Energy CT in Patients With Osseous Metastases From Castrate-resistant Prostate Cancer
The purpose of this study is to establish a more accurate and precise way to image (take pictures of) metastatic bone disease in patients with prostate cancer for staging and monitoring response to therapy.
- Trial name
- NCT03111914
- Testing
- Dual Energy Computed Tomography
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University
Cancer
Dual Energy CT: A New Method for Better Dose Calculation in Proton Beam Therapy
Researchers want to compare proton stopping ratios, used for proton beam therapy planning, calculated based on single energy CT and dual energy CT images; with the intension of improve upon the proton range determination.
- Trial name
- (DUAL) (NCT02722109)
- Testing
- No intervention
- Volunteers
- 14 people
- Sponsor
- Aarhus University Hospital
Renal Cancer
Dual-energy SPEctral CT to Evaluate Response to First-line Therapies in Patients With Metastatic Clear Cell REnal Cancer
To evaluate the utility of dual-energy spectral computed tomography (CT) scan in monitoring treatment in patients with metastatic clear cell carcinoma of the kidney.
- Trial name
- SPECTRE (NCT06863857)
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
PET CT
PET-DECT for Staging and Imaged Based Radiotherapy Planning in Lung Cancer
The overall goal of this project is to investigate the diagnostic performance of integrated F-18 fluorodeoxyglucose-positron emission tomography (FDG-PET) and Dual Energy CT (DECT) imaging in determining the thoracic nodal status…
- Trial name
- NCT03146117
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical University of South Carolina
Lung Perfusion
LUng voluMe reductIoN by DuAl ENergy CT Evaluation (LUMINANCE) Study
The purpose of this research study is to see if a special CT scan (dual-energy CT) provides useful information in patients undergoing bronchsoscopic lung volume reduction (valve placement for emphysema).
- Trial name
- NCT05816239
- Testing
- Dual Energy CT
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Sameer Avasarala
Gallstone
Diagnostic Performance of Dual Energy CT for the Detection of Gallbladder Gallstones
To assess diagnostic performance of Dual Energy CT fo gallblader gallstone detection.
- Trial name
- DUAL-GB (NCT05704907)
- Testing
- gallbladder ultrasound
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Scoliosis
Low-dose Dual-energy CT for the Pre-surgical Planning of Patients With Progression of Scoliosis
The aim of the study is to evaluate the diagnostic accuracy of low-dose dual energy CT in the pre-surgical planning of patients with progression of scoliosis
- Trial name
- NCT03483844
- Testing
- GE CT 750 HD
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Istituto Ortopedico Rizzoli
Coronary Arteriosclerosis
Characteristics of Culprit Lesion and Changes in Plaque Composition. A Dual Energy Cardiac CT Study
Identifying patients who are at risk for a future myocardial infarction, is still one of the biggest challenges in cardiology. In this study the investigators will investigate culprit lesion in patients with NSTEMI and the…
- Trial name
- S-20130009 (NCT02639962)
- Testing
- Cardiac CT
- Where
- Denmark
- Volunteers
- 135 people
- Sponsor
- Odense University Hospital
Oral Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma
Dual-energy CT vs. MRI in the Evaluation of Squamous Cell Carcinomas of the Oral Cavity and Oropharynx
The diagnostic and pre-therapeutic assessment of squamous cell carcinomas requires a neck and chest CT scan and a neck and facial MRI, which is the most effective examination, to establish the TNM stage of the tumor.
- Trial name
- DECT-CEco (NCT07343271)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Cardiovascular Diseases
Dual Energy Cardiac CT Data Collection and Evaluation
This study is intended to collect clinical feasibility data using this prototype research mode for the purposes of understanding potential clinical impact, potential limitations and strengths, and to further develop the technique…
- Trial name
- NCT05171764
- Testing
- Additional Gemstone Spectral Imaging (GSI) cardiac scan
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- GE Healthcare
Pulmonary Hypertension
Quantitative Dual Energy Computed Tomography in Pulmonary Hypertension
Pathophysiological mechanisms leading to pulmonary hypertension (PH) are complex. Quantitative computed tomography (QCT) can help us to study morphological alterations in patients with PH.
- Trial name
- DECTPH (NCT03901287)
- Testing
- dual energy CT scans
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Bordeaux
Atherosclerotic Disease
Spectral CT Protocol Optimization for Atherosclerotic Plaque CharacterizatION
The SCORPION study (Spectral CT Protocol Optimization for Atherosclerotic Plaque Characterization) is a retrospective and prospective observational research project aimed at improving the diagnostic accuracy of dual-energy CT…
- Trial name
- SCORPION (NCT06886958)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS SYNLAB SDN
Brain Metastases, Bone Metastases
Dual Energy CT - a Tool for Delineation of Tumor and Organs at Risk in Radiotherapy
The primary aim of this clinical study, 'Dual Energy CT - a tool for delineation of tumor and organs at risk in radiotherapy' (DART) is to evaluate whether dual-energy CT (DECT) is at least as effective as magnetic resonance…
- Conditions
- Brain Metastases, Bone Metastases, Head and Neck Cancer, Lung Cancer
- Trial name
- DART (NCT07185958)
- Testing
- Dual-energy CT (DECT), Iodine-based contrast agent, Magnetic Resonance Imaging (MRI)
- Where
- 3 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Aalborg University Hospital
Supra-Aortic Stenosis
Comparison of Spectral Photon Counting CT (SPCCT) With Dual Energy CT (DECT) and Magnetic Resonance Imaging (MRI) for Plaque and Lumen Carotid Arteries Evaluation
In this study, the investigator propose to determine the efficiency of a new and more sophisticated imaging prototype, the Spectral Photon Counting Computed Tomography (SPCCT), at characterizing vulnerable plaques and luminal…
- Trial name
- CAPL (NCT04466787)
- Testing
- Spectral Photon Counting Computed Tomography (SPCCT), Dual Energy CT (DECT)
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Hospices Civils de Lyon
Bowel Ischemia, Acute Bowel Ischemia / Infarction
Diagnosing Acute Onset Insufficient Intestinal Blood Flow (Bowel Ischemia) With a Novel CT Technique Called Dual-energy CT (DECT). This Observational Study Seeks to Evaluate Whether DECT Can Improve the Diagnosis of Bowel Ischemia and How the DECT Findings Correlate With Intraoperative Findings
The aim of this study is to evaluate the performance of dual-energy CT (DECT) in the diagnosis of acute bowel ischemia (ABI). ABI is a condition characterised by inadequate blood supply to portions of the intestine.
- Trial name
- NCT04561323
- Testing
- Dual-energy CT
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet