Clinical trials: Dual-energy CT
Gastrointestinal Stromal Tumor (GIST)
Unifying Advanced Treatment With Advanced Imaging
The study investigates response assessment of gastrointestinal stromal tumors using Dual Energy CT (DECT) in patients undergoing targeted therapy with a TKI Inhibitor.
- Trial name
- GISTm3 (NCT03404076)
- Testing
- Dual Energy CT
- Where
- Germany
- Volunteers
- 93 people
- Sponsor
- Heidelberg University
Gastrointestinal Lesions
Photon-Counting CT for Detection of Small Gastrointestinal Lesions
This comparative matched-cohort study aims to evaluate the diagnostic performance of contrast-enhanced photon-counting computed tomography (PCCT) for detecting small gastrointestinal lesions compared with energy-integrating…
- Trial name
- PCCT-GI (NCT07748923)
- Testing
- Contrast-Enhanced Photon-Counting Computed Tomography, Contrast-Enhanced Energy-Integrating Detector Dual-Energy Computed Tomography
- Where
- China
- Volunteers
- 1,762 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Renal Cell Carcinoma, Renal Cysts
Dual Energy CT vs Standard Triple Phase CT-A Randomised Control Trial
To compare SBDECT with standard Triple Phase Multi-Detector CT (TPMDCT) in renal mass evaluation in terms of appropriateness of treatment received after diagnosis. To determine SBDECT diagnostic accuracy.
- Conditions
- Renal Cell Carcinoma, Renal Cysts, Transitional Cell Carcinoma, AML
- Trial name
- NCT02160600
- Testing
- Standard multiphase CT, split bolus Dual energy CT
- Where
- India
- Volunteers
- 124 people
- Sponsor
- All India Institute of Medical Sciences
Crohn's Disease
Dual Energy Computerized Tomography (DE-CT) in Patients With Crohn's Disease
This study aims to evaluate the accuracy of dual energy computerized tomography (DE-CT) in predicting the need for surgery in patients with Crohn's disease and intestinal lesions with obstructive symptoms.
- Trial name
- NCT02341755
- Where
- Israel
- Volunteers
- 38 people
- Sponsor
- Shaare Zedek Medical Center
Fractures, Bone, Bone Marrow Edema
Prospective Study of Diagnostic Accuracy of Spectral CT for the Detection of Bone Marrow Edema
Dual-Energy/Multi-Energy/Spectral-CT can visualize bone marrow edema associated with fractures, however, current scientific evidence is mostly derived from to retrospective analyses.
- Trial name
- NCT04963127
- Testing
- Computed Tomography of the skeleton using a Dual-Energy-/Multi-Energy-/Spectral acquisition mode, Computed Tomography of the skeleton using a conventional single-energy / non-spectral acquisition mode
- Where
- Germany
- Volunteers
- 800 people
- Sponsor
- University Hospital Augsburg
Gastric Cancer, CT
Energy CT in Imaging and Diagnosis of Gastric Cancer
Accurate preoperative prediction of risk stratification, treatment response, and survival prognosis in gastric cancer is important for improving clinical treatment decisions, prolonging patient survival, and improving patient…
- Trial name
- CTIDGC (NCT06869694)
- Testing
- computerized tomography
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Compression Fracture of Thoracic Vertebral Body, Spinal Compression Fracture
Dual-energy CT in Detecting Bone Marrow Edema of Vertebral Compression Fractures
The purpose of this study is to 1. Assess bone marrow edema within the VCF by use of a DE CT virtual noncalcium image compared with MR imaging as standard reference. 2.
- Trial name
- NCT01281826
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Cheng-Kung University Hospital
Multiple Myeloma (MM)
PET-Enabled Dual-Energy CT in Multiple Myeloma
This pilot study will evaluate a new imaging method called PET-enabled dual-energy CT for measuring bone and soft-tissue composition in bone marrow.
- Trial name
- NCT07646873
- Testing
- PET-enabled dual-energy CT imaging, X-ray dual-energy CT imaging
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Non-small Cell Lung Cancer Stage III
Pilot Study of a Novel Type of CT Scan to Assess Treatment Response During Chemoradiotherapy for Stage III Non-Small Cell Lung Cancer
Dual-energy CT (DECT) provides information on the blood volume in tumors and lymph nodes. As tumors respond to treatment, preliminary data suggests that the blood volumes changes as well.
- Trial name
- NCT02053285
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rush University Medical Center
Liver Disease
Quantitative Diagnosis of Fatty Liver by Dual Energy CT Technique
This study is proposed to explore the correlation between fatty content of fatty liver and the difference of CT attenuation value in men using dual-energy CT, and to set up a threshold for diagnosis of fatty liver.
- Trial name
- NCT00172705
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obesity
Technical Validation of Lunar iDXA Visceral Fat Tool
The goal of this project is to compare visceral fat measurements derived from Lunar iDXA total body scans and from Computed Tomography (CT) scans of the abdominal region for a Chinese population.
- Trial name
- NCT01110161
- Testing
- Visceral fat mass measurement
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
HCC
"Double Low-Dose" DECT for HCC Imaging
Hypothesis: double low-dose protocol provide better lesion conspicuity than standard protocol CT in patients at high-risk of HCC.
- Trial name
- NCT03045445
- Testing
- Double Low-Dose protocol CT, Standard protocol CT
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Spinal Metastases
Evaluation of Spinal Metastatic Tumour for Aggressive Spinal Sugery by Dual Energy CT
Metastatic vertebral disease is a major hazard for oncological patients because the performance and life quality will substantially deteriorate if presence of neoplastic compression.
- Trial name
- NCT03631095
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- National Taiwan University Hospital
Head and Neck Squamous Cell Carcinoma
Dual-Energy CT in Patients With Head and Neck Squamous Cell Carcinomas
The purpose of this study is to utilize dual-energy computed tomography (DECT) to investigate changes in tumor iodine concentration in patients with head and neck squamous cell carcinomas (HNSCC).
- Trial name
- NCT02279459
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Ottawa Hospital Research Institute
Bowel; Ischemic, Chronic, Tomography, X-Ray Computed
A Pilot Study on the Using a Newer Computed Tomography (CT) Based Technique for the Detection of Altered Bowel Blood Flow Among Patients Suffering From Chronic Mesenteric Ischemia During Meal Digestion.
Chronic meseteric ischemia (CMI) is a disease characterized by an insufficient blood supply to the intestines due to a narrowing (stenosis) of one or multiple intestinal arteries.
- Conditions
- Bowel; Ischemic, Chronic, Tomography, X-Ray Computed, Dual-energy CT
- Trial name
- NCT04794959
- Testing
- Dual-energy CT
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ischemia
Dual Energy CT for Ischemia Determination Compared to "Gold Standard" Non-Invasive and Invasive Techniques
The purpose of this study is determine the diagnostic performance of dual energy computed tomography perfusion for non-invasive assessment of the hemodynamic significance of coronary stenosis, as compared to a direct measurement…
- Trial name
- DECIDE-Gold (NCT02178904)
- Testing
- CT and stress test
- Where
- 5 sites in United States
- Volunteers
- 156 people
- Sponsor
- Weill Medical College of Cornell University
Gastroesophageal Varices
Dual Energy CT as a Noninvasive Method to Screen for Gastroesophageal Varices
Cirrhosis leads to portal hypertension and development of gastroesophageal varices, which are the most common cause for bleeding in cirrhosis and a major cause of death.
- Trial name
- NCT03910413
- Testing
- Duel Energy CT
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Alabama at Birmingham
Rectal Cancer
Preoperative Assessment of Mesorectal Lymph Nodes by Dual Energy CT. PUMK-DECT
Endpoints subproject 1: To develop a reproducible method for the detection of lymph nodes by DECT in operation specimens from rectal resection for cancer.
- Trial name
- NCT02592304
- Testing
- Dual energy computed tomography
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Pancreatic Cyst
Comparison Between Dual Energy/Subtraction CT With MRI for the Identification of Predictors of Malignancy in Cystic Pancreatic Lesions
Cystic pancreatic lesions are increasingly detected incidentally in imaging studies, reportedly in up to 45% of the abdominal Magnetic Resonance (MR) examinations.
- Trial name
- NCT03320733
- Testing
- Dual energy CT scan with subtraction imaging
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- University Health Network, Toronto
Osteoarthritis, Hand Osteoarthritis
Diagnostic Accuracy of Dual-energy CT
The study will include 20 people with hand OA awaiting surgery in the fingers. Participants will undergo dual-energy CT, cone-beam CT, ultrasound, clinical examination, blood sampling and questionnaires.
- Conditions
- Osteoarthritis, Hand Osteoarthritis, Crystal; Deposit Joint, Crystals; Arthritis, Pyrophosphate
- Trial name
- DAD (NCT04585113)
- Testing
- CT-scanning
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Henning Bliddal