Clinical trials: Duloxetine
Panic Disorder
The Efficacy and Tolerability of Duloxetine for the Treatment of Panic Disorder
The purpose of this study is to determine whether duloxetine is effective in the treatment of panic disorder.
- Trial name
- NCT00438971
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital
Diabetic Neuropathies
Duloxetine Versus Placebo in the Treatment of Patients With Diabetic Peripheral Neuropathic Pain in China
To determine if duloxetine 60mg up to 120mg daily can work in treating pain from Diabetic Neuropathy.
- Trial name
- NCT00408993
- Testing
- Duloxetine Hydrochloride
- Where
- 7 sites in China
- Volunteers
- 215 people
- Sponsor
- Eli Lilly and Company
Depression
A Study Comparing Duloxetine to Other Antidepressants in the Treatment of Severe Depression
The purpose of this study is to compare duloxetine with other antidepressants in the treatment of severe depression.
- Trial name
- TRY FIRST (NCT00666757)
- Testing
- duloxetine, fluoxetine, citalopram
- Where
- 61 sites in United States
- Volunteers
- 750 people
- Sponsor
- Eli Lilly and Company
Sphincter of Oddi Dysfunction
Duloxetine in Patients With Suspected Functional Pancreatic/Biliary Pain (Sphincter of Oddi Dysfunction)
Open-label single center study of duloxetine in patients with SOD who have failed to respond to the standard treatments. This protocol is designed to explore the tolerability and efficacy of Duloxetine in the management of…
- Trial name
- SOD (NCT00471315)
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Medical University of South Carolina
Major Depressive Disorder
A Study in Depression and Associated Painful Physical Symptoms
The purpose of this study is to find out if 60 mg of duloxetine given once a day by mouth for 8 weeks to patients diagnosed with major depressive disorder, who also report associated painful physical symptoms, is better than…
- Trial name
- NCT01070329
- Testing
- Duloxetine
- Where
- 34 sites in United States, Puerto Rico
- Volunteers
- 527 people
- Sponsor
- Eli Lilly and Company
Depression
Identifying Factors That Predict Antidepressant Treatment Response
This study will compare different treatments for depression in order to identify which factors predict effectiveness, and will include a companion study which investigates combining treatments and long term effectiveness.
- Trial name
- NCT00360399
- Testing
- Escitalopram, Duloxetine, Cognitive behavioral therapy (CBT)
- Where
- 2 sites in United States
- Volunteers
- 344 people
- Sponsor
- Emory University
Irritable Bowel Syndrome, Generalized Anxiety Disorder
An Open Label Trial of Duloxetine in the Treatment of Irritable Bowel Syndrome and Comorbid Generalized Anxiety Disorder
The investigators propose to evaluate the effectiveness of duloxetine in treating subjects with both Irritable Bowel Syndrome (IBS) and Generalized Anxiety Disorder (GAD).
- Trial name
- NCT00961298
- Testing
- Duloxetine
- Volunteers
- 17 people
- Sponsor
- West Penn Allegheny Health System
Binge Eating, Depression
Study of Duloxetine vs Placebo in Treatment of Binge Eating Disorder With Depression
The purpose of this research study is to test the safety of duloxetine and see what effects (good and bad) it has on the subject's binge eating disorder and comorbid depressive disorder (depression occurring with binge eating…
- Trial name
- NCT00607789
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Cincinnati
Generalized Anxiety Disorder
Duloxetine for the Treatment of Generalized Anxiety Disorder
This is a 15 week study comparing how well duloxetine and placebo treatments improve generalized anxiety disorder
- Trial name
- NCT00803361
- Testing
- Duloxetine
- Where
- 7 sites in China
- Volunteers
- 210 people
- Sponsor
- Eli Lilly and Company
Major Depressive Disorder, Healthy Participants
A Study of the Neurobiology of Depression
Previous research studies have shown that depression is associated with changes in structure and activity in different parts of the brain and that antidepressant medication can affect brain activity in different parts of the…
- Trial name
- NCT01051466
- Testing
- Duloxetine
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Depressive Disorder
A Study of Duloxetine (LY248686) in the Treatment of Japanese Children and Adolescents With Depressive Disorder
The purpose of this long-term study is to evaluate the safety and efficacy of duloxetine hydrochloride in Japanese children and adolescents with depressive disorder.
- Trial name
- NCT03395353
- Testing
- Duloxetine Hydrochloride
- Where
- Japan
- Volunteers
- 151 people
- Sponsor
- Shionogi
Major Depressive Disorder
A Study of Duloxetine in Major Depressive Disorder (MDD) and Associated Painful Symptoms
The purpose of this study is to find out if 60 mg of duloxetine given once a day by mouth for 8 weeks to patients diagnosed with major depressive disorder, who also report associated painful physical symptoms, is better than…
- Trial name
- NCT01000805
- Testing
- Duloxetine
- Where
- 37 sites in United States, France and 4 more
- Volunteers
- 528 people
- Sponsor
- Eli Lilly and Company
Diabetic Peripheral Neuropathic Pain
A Study of Duloxetine (LY248686) in Participants With Diabetic Peripheral Neuropathic Pain (DPNP)
The main purpose of this study is to evaluate the effectiveness and safety of the study drug known as duloxetine in participants with diabetic peripheral neuropathic pain.
- Trial name
- NCT02417935
- Testing
- Duloxetine, Pregabalin
- Volunteers
- 304 people
- Sponsor
- Eli Lilly and Company
Depressive Disorder, Major
Study to Assess Clinical Response of Duloxetine in Patients Hospitalized for Severe Depression
Study to assess efficacy of Duloxetine 120 mg and Duloxetine 60 mg in patients hospitalized for severe depression after 4 weeks of treatment. To evaluate the rescue option in non-responding patients.
- Trial name
- NCT02229825
- Testing
- Duloxetine
- Volunteers
- 339 people
- Sponsor
- Boehringer Ingelheim
Alcohol Dependence
Duloxetine Versus Pregabalin for Alcohol Dependence
A 12-week, double-blind, placebo-controlled parallel group study will be conducted with 150 outpatients with alcohol dependence, with random assignment to pregabalin 300 mg/d, duloxetine 40 mg/d, or placebo in conjunction with…
- Trial name
- NCT00929344
- Testing
- Pregabalin, Duloxetine, Standardized behavioral therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The Scripps Research Institute
Fibromyalgia
A Study of Duloxetine in Fibromyalgia
The purpose of the study is to assess the effectiveness and safety of duloxetine in participants with fibromyalgia.
- Trial name
- NCT01552057
- Testing
- Duloxetine 60 mg
- Where
- Japan
- Volunteers
- 393 people
- Sponsor
- Eli Lilly and Company
HIV Infections, Peripheral Neuropathy
Combination Pain Therapy in HIV Neuropathy
Neuropathy results from damage to the nerves in the feet and legs. It is usually experienced as pain, tingling or numbness. In HIV-infected people, neuropathy can result from the infection itself or be a side effect of…
- Trial name
- NCT00863057
- Testing
- Duloxetine, Methadone
- Where
- 8 sites in United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Osteoarthritis
A Study of Duloxetine in Participants With Chronic Pain Due to Osteoarthritis in China
The purpose of this study is to assess the efficacy and safety of duloxetine once daily compared with placebo on the reduction of pain due to osteoarthritis (OA) in knee or hip in participants in China.
- Trial name
- NCT01931475
- Testing
- Duloxetine
- Where
- 12 sites in China
- Volunteers
- 407 people
- Sponsor
- Eli Lilly and Company
Osteoarthritis Knee Pain
Duloxetine vs. Placebo in the Treatment of Osteoarthritis Knee Pain
The primary purpose of this study is to determine if duloxetine reduces pain severity in patients with osteoarthritis knee pain.
- Trial name
- NCT00433290
- Testing
- Duloxetine
- Where
- 7 sites in United States, Greece and 2 more
- Volunteers
- 256 people
- Sponsor
- Eli Lilly and Company
Osteoarthritis
Duloxetine in Osteoarthritis (OA) Pain
This study aims to determine in people with knee Osteoarthritis (OA) if relief of pain after treatment with either duloxetine or placebo is associated with changes in brain anatomy.
- Trial name
- NCT01558700
- Testing
- Duloxetine, Sugar pill
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwestern University