Clinical trials: Duloxetine
Depressive Disorder, Major
A Randomized Double Blind Study Evaluating Duloxetine in Outpatients With MDD and Pain
To determine the efficacy of Duloxetine vs. placebo on pain as determined by change in the Brief Pain Inventory (BPI) from baseline over 8 weeks of treatment
- Trial name
- NCT00191919
- Testing
- Duloxetine Hydrochloride
- Where
- 38 sites in Belgium, Czechia and 4 more
- Volunteers
- 310 people
- Sponsor
- Eli Lilly and Company
Infertility, Male, Depression
Impact of Duloxetine on Male Fertility
The investigators are conducting a placebo-controlled, randomized control trial with duloxetine in healthy, fertile men not previously on any antidepressants.
- Trial name
- NCT03038867
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Depression, Pain
Subject Information and Consent Form F1J-US-HMCB Duloxetine Once-Daily Dosing Versus Placebo in Patients With Major Depression and Pain
The purposes of this study are to determine whether an investigational drug can help patients suffering from major depression with pain symptoms, and gather data on the safety of the investigational drug including any side…
- Trial name
- NCT00036335
- Testing
- Duloxetine Hydrochloride
- Where
- 25 sites in United States
- Volunteers
- 286 people
- Sponsor
- Eli Lilly and Company
Fibromyalgia
A Study Comparing Duloxetine and Placebo in the Treatment of Fibromyalgia
The purpose of this study is to confirm the efficacy and safety of duloxetine 60-120 mg once daily in comparison to placebo on symptom improvement in patients meeting criteria for fibromyalgia aged 18 and older.
- Trial name
- NCT00673452
- Testing
- duloxetine hydrochloride
- Where
- 46 sites in United States, Puerto Rico
- Volunteers
- 530 people
- Sponsor
- Eli Lilly and Company
Chronic Phantom Limb Pain
Open Label Study of Duloxetine for the Treatment of Phantom Limb Pain
This is a study to assess the possible benefit of duloxetine in the treatment of chronic phantom limb pain.
- Trial name
- NCT00425230
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Stress Urinary Incontinence
To Evaluate the Safety of Duloxetine in Patients With Stress Urinary Incontinence
The patients are being followed in this study to determine the safety of taking the medication Duloxetine for a long period of time. The patients participating in this study suffer from Stress Urinary Incontinence.
- Trial name
- NCT00190645
- Testing
- Duloxetine
- Where
- 2 sites in United States, Canada
- Volunteers
- 600 people
- Sponsor
- Eli Lilly and Company
Generalized Anxiety Disorder
A Study of Duloxetine in Elderly Generalized Anxiety Disorder
The purpose of this study is to test the safety and efficacy of duloxetine versus placebo in elderly patients suffering from generalized anxiety disorder (GAD).
- Trial name
- NCT01118780
- Testing
- Duloxetine
- Where
- 25 sites in United States, Argentina and 7 more
- Volunteers
- 291 people
- Sponsor
- Eli Lilly and Company
Binge Eating, Depression
Study of Duloxetine vs Placebo in Treatment of Binge Eating Disorder With Depression
The purpose of this research study is to test the safety of duloxetine and see what effects (good and bad) it has on the subject's binge eating disorder and comorbid depressive disorder (depression occurring with binge eating…
- Trial name
- NCT00607789
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Cincinnati
Major Depression
Study of Brain Response to Emotional Pictures Using a fMRI While on Duloxetine
The purpose of this study is to find out what parts of the brain have increased or decreased activity when people are depressed and how antidepressant medicine changes this activity in depressed patients.
- Trial name
- NCT00532480
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Chemotherapy-induced Peripheral Neuropathy
Capsaicin 179 mg Patch Versus Oral Duloxetine in Patients With Chemotherapy-induced Peripheral Neuropathy
Chemotherapy induced peripheral neuropathy (CIPN) is a frequent and disabling complication of systemic chemotherapy, particularly with oxaliplatin or taxanes.
- Trial name
- CAPNEUCHIM (NCT05840562)
- Testing
- Capsaicin, Duloxetine
- Where
- 11 sites in France
- Volunteers
- 274 people
- Sponsor
- Institut Cancerologie de l'Ouest
Urinary Incontinence, Stress
Effectiveness and Safety of Duloxetine in Women Experiencing Urinary Leakage Due to Physical Stress and Urge.
The purpose of the study is to evaluate the effectiveness of duloxetine in reducing urinary incontinence(leakage of urine)occurrences in women due to physical stress and leakage that occurs during a strong need(urge) to urinate.
- Trial name
- NCT00190814
- Testing
- duloxetine
- Where
- 3 sites in United States, Canada and 1 more
- Volunteers
- 600 people
- Sponsor
- Eli Lilly and Company
CIPN, CIPN - Chemotherapy-Induced Peripheral Neuropathy
Comparison of the Efficacy and Safety of Mirogabalin and Duloxetine in Chemotherapy-induced Peripheral Neuropathy in a Randomized Controlled Trial: a Quality of Life Study in Cancer Survivors
To conduct a two-arm, parallel, prospective, randomized controlled, open-label trial to compare the efficacy of the novel drug mirogabalin with the conventional treatment duloxetine in reducing pain associated with…
- Conditions
- CIPN, CIPN - Chemotherapy-Induced Peripheral Neuropathy, CIPN in Adjuvant Breast Cancer Patients, Duloxetine
- Trial name
- NCT06711978
- Testing
- Mirogabalin, Duloxetine
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Pusan National University Yangsan Hospital
Diabetes Mellitus, Peripheral Neuropathies
Effects of Pregabalin, Duloxetine & Amitriptyline on Pain & Sleep
The purpose of this study is to assess the effectiveness of pregabalin, duloxetine and amitriptyline compared with placebo in reducing pain in diabetic patients as assessed by Brief Pain Inventory (BPI).
- Trial name
- NCT00370656
- Testing
- Pregabalin, Duloxetine, Amitriptyline
- Where
- 3 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- University of Surrey
Dysthymic Disorder, Depressive Disorder NOS
Duloxetine for Chronic Depression: a Double-blind Study
The investigators are studying a new antidepressant medicine, duloxetine, for the treatment of people with chronic depression. Duloxetine (trade name Cymbalta) was recently approved by the FDA for the treatment of major…
- Trial name
- NCT00360724
- Testing
- Duloxetine (Cymbalta)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- New York State Psychiatric Institute
Worry, Anxiety
Effects of Duloxetine on Pathological Worry in Patients With Generalized Anxiety Disorder: A fMRI Study
(1) to compare the differences of neural activation of pathological worry between pre-treatment GAD patients and normal subjects; (2) to measure the differences of brain activation on worry in GAD patients before and after…
- Trial name
- NCT00491348
- Testing
- duloxetine hydrochloride
- Where
- Taiwan
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Depressive Disorder
A Comparison of Tolerability and Efficacy of Different Doses of Duloxetine for the Treatment of Major Depressive Disorder
The purpose of this study is to compare the tolerability and efficacy of different doses of duloxetine in patients with major depressive disorder.
- Trial name
- NCT00191061
- Testing
- duloxetine hydrochloride
- Where
- 32 sites in United States
- Volunteers
- 640 people
- Sponsor
- Eli Lilly and Company
Urinary Incontinence, Stress
Evaluate Safety and Efficacy of Duloxetine in Predominant Stress Urinary Incontinence
The purposes of this study are to determine whether duloxetine can help subjects with stress urinary incontinence and to see whether the effects of duloxetine can be maintained.
- Trial name
- NCT00190996
- Testing
- Duloxetine Hydrochloride
- Where
- United Kingdom
- Volunteers
- 2,765 people
- Sponsor
- Eli Lilly and Company
Fatigue Syndrome, Chronic
Double Blind Trial of Duloxetine in Chronic Fatigue Syndrome
The purpose of this study is to determine the safety and efficacy of duloxetine compared with placebo for reducing fatigue in patients diagnosed with Chronic Fatigue Syndrome (CFS).
- Trial name
- CFS (NCT00375973)
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Depression
Functional Neuroanatomy and Regional Metabolism Before and After Treatment With Duloxetine
The findings may guide future investigations on novel therapeutic targets in depressive subjects. Based on the depicted link between personality traits and altered brain metabolism and function, the latter might be used as…
- Trial name
- NCT02658617
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Heinz Boeker
Major Depressive Disorder
Leveraging EEG for Antidepressant Prediction With Duloxetine and Bupropion
The LEAP-DB study will be conducted to validate the utility of EEG biomarkers as an aid to antidepressant treatment selection in adults with MDD.
- Trial name
- LEAP-DB (NCT04388189)
- Testing
- Duloxetine, Bupropion
- Sponsor
- Alto Neuroscience