Clinical trials: Duration of Operation
Surgical Wound Infection, Head and Neck Neoplasms
Prophylactic Antibiotic Duration in Head and Neck Cancer Surgery (PROTECT-HN Trial)
The goal of this clinical trial is to learn whether giving antibiotics for 7 days after surgery, instead of the usual 24 hours, lowers the chance of wound infection in adults having major surgery for mouth or throat cancer.
- Conditions
- Surgical Wound Infection, Head and Neck Neoplasms, Oral Cancer Neoplasms, Pharyngeal Neoplasms
- Trial name
- PROTECT-HN (NCT07851857)
- Testing
- Ampicillin/Sulbactam 24-Hour Postoperative Prophylaxis, Ampicillin/Sulbactam 7-Day Postoperative Prophylaxis
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- AC Camargo Cancer Center
Coronary Artery Disease, Internal Mammary-Coronary Artery Anastomosis
Fibrin Clot Properties and Blood Loss Following Coronary Artery By-pass Grafting
Up to 15% of operations in cardio-pulmonary by-pass are complicated by excessive postoperative blood loss, which negatively affects the outcomes.
- Conditions
- Coronary Artery Disease, Internal Mammary-Coronary Artery Anastomosis, Coronary Artery Bypass, Blood Loss, Postoperative
- Trial name
- NCT03622671
- Testing
- Skeletonized LIMA, Pedicled LIMA
- Where
- Poland
- Volunteers
- 62 people
- Sponsor
- Jagiellonian University
Pelvic Floor Disorders, Ureter; Kink
Ureteric Visualization: Vitamin B Vs 5% Dextrose in Water
Background: The risk of ureteric injury at the time of pelvic reconstructive surgery can be as high as 3% and the American College of Obstetricians and Gynecologists has stated that intraoperative cystoscopy should be done after…
- Trial name
- NCT03089671
- Testing
- Vitamin B (riboflavin, vitamin B2), 5% Dextrose in Water (D5W)
- Where
- 2 sites in Canada
- Volunteers
- 238 people
- Sponsor
- Mount Sinai Hospital, Canada
Advanced Ovarian Cancer
The IPLA-OVCA Trial, Intra-Peritoneal Local Anaesthetics in Ovarian Cancer
Surgery and chemotherapy combined constitute first line treatment in women with advanced ovarian cancer. The aim of surgery apart from staging is cytoreduction, i.e. surgical resection of tumour.
- Trial name
- IPLA-OVCA (NCT04065009)
- Testing
- Ropivacaine, Saline Solution
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Karolinska Institutet
VATS, Lung
The Comparison of Navigational Bronchoscopic and CT-Guided Preoperative Markings in Minimally Invasive Thoracic Surgery
This clinical trial aims to determine whether navigational bronchoscopic or CT-guided marking is more effective for localizing small pulmonary nodules in minimally invasive thoracic surgery.
- Conditions
- VATS, Lung, ICG (Indocyanine Green)
- Trial name
- NaviGuide (NCT06957600)
- Testing
- Preoperative marking
- Where
- Hungary
- Volunteers
- 66 people
- Sponsor
- Semmelweis University
Post Induction Hypotension, Postoperative Morbidity
Preoperative Carotid Doppler Ultrasound Parameters for Prediction of Post-Induction Hypotension in Elective Non-Cardiac Surgery
This prospective observational study aims to evaluate the predictive value of preoperative carotid Doppler ultrasound parameters, including carotid velocity-time integral (carotid VTI) and corrected carotid flow time (ccFT), for…
- Trial name
- NCT07488182
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Necmettin Erbakan University
Non-cardiac Surgery
Promotion of Ambulation Before Non-cardiac Surgery
Primary Determine the impact of prescribing a routine pre-surgical walk scheduled compared to conventional intervention (not recommended exercise) in reducing the length of hospital stay and the time of onset of ambulation during…
- Trial name
- PAMP-Phase2 (NCT03213496)
- Testing
- Walk prescription, Conventional care
- Where
- 2 sites in Colombia
- Volunteers
- 368 people
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Postoperative Pain Management, Postoperative Pain
Evaluation of Effectivity of Quadratus Lumborum Blocks With Adjuvant
İn recent years abdominal wall blocks are widely used for to reduce intraoperative anesthetic recuirements and postoperative analgesia.Quadratus lumborum blocks are one of the abdominal wall blocks to used at laparoscopic…
- Conditions
- Postoperative Pain Management, Postoperative Pain, Analgesia, Nerve Blocks
- Trial name
- AdjuvantQLB (NCT06028061)
- Testing
- Adjuvant-free Quadratus lumborum block, Quadratus lumborum block III with Adjuvant
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
First-attempt Success Rate of Real-time Ultrasound-guided Thoracic Epidural Catheter Placement
Application of Real-time Ultrasound Guidance in Thoracic Epidural Catheter Placement
The goal of this clinical trial is to assess the success rate of real-time ultrasound-guided thoracic epidural catheter placement at the first attempt in patients who will undergo thoracic or abdominal surgeries.
- Trial name
- NCT07100769
- Testing
- Real-time ultrasound-guided thoracic epidural placement
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Coronary Artery Disease
Residents' Learning Curve of Intraoperative Transit-time Flowmetry and High-frequency Ultrasound in CABG (LEARNERS)
Transit-time flowmetry (TTFM) allows grafts quality assessment during coronary artery bypass surgery by measuring the flow volume through them.
- Trial name
- LEARNERS (NCT06589323)
- Testing
- Coronary artery bypass graft
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hemiarthroplasty, Arthroplasty, Replacement, Hip
Effects of Surgery Start Time on Postoperative Interleukin-6, Interleukin-8, and Cortisol
Cortisol is a hormone that increases after trauma or surgery and has circadian rhythm. It has a form that is increased in the morning and decreased in the evening.
- Trial name
- NCT03076827
- Testing
- Total hip replacement, Hemi-arthroplasty
- Volunteers
- 44 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Laparoscopic Pancreaticoduodenectomy
Analysis of Intraoperative Bleeding Characteristics in Laparoscopic Pancreaticoduodenectomy
In this study, we analyze the common bleeding characteristics in laparoscopic pancreaticoduodenectomy by reviewing and annotating bleeding information from previous surgical videos as well as surgical operation OSATS technique…
- Trial name
- NCT06128603
- Testing
- laparoscopic pancreaticoduodenectomy
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xinrui Zhu，MD
Cholecystectomy, Laparoscopic, Noise
The Effect of Noise Control During Anesthesia Induction in Laparoscopic Cholecystectomy Surgery
This study aims to determine the effects of active and passive noise control method and headphone usage and noise level during anesthesia induction in laparoscopic cholecystectomy surgery on hemodynamic parameters, pain, nausea…
- Conditions
- Cholecystectomy, Laparoscopic, Noise, Anesthesia Induction
- Trial name
- Anesth-noise (NCT06666686)
- Testing
- Active noise control headphone, Passive noise control headphone
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Malocclusion
Comparing of the Clinical Outcome of Periodontal Accelerated Osteogenic Orthodontics With Horizontal or Vertical Releasing Incisions
The study aims to compare the effect of periodontal accelerated osteogenic orthodontics (PAOO) with horizontal or vertical releasing incisions on operation time, healing, adverse effects, and effectiveness of bone augmentation.
- Trial name
- NCT05441683
- Testing
- horizontal extending incision, vertical releasing incision
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pulmonary Malformations, Child
Impact of Forced Expiration On Pleural Drainage Duration (KPDP)
Following thoracic surgery, pleural effusion in pleural cavity requires post-operative drainage. Pleural effusion is responsible for pulmonary congestion, atelectasis, hypoventilation, lower efficacy of diaphragmatic curse, lower…
- Trial name
- KPDP (NCT02660203)
- Testing
- Forced expiration
- Where
- 10 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Tours
Glioblastoma Multiforme, Anaplastic Astrocytoma
Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor
This is a multicenter study evaluating the safety and tolerability of Toca 511 administered intravenously to patients with recurrent or progressive Grade III or Grade IV Gliomas who have elected to undergo surgical removal of…
- Conditions
- Glioblastoma Multiforme, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Anaplastic Oligoastrocytoma
- Trial name
- NCT01985256
- Testing
- Toca 511, Toca FC
- Where
- 6 sites in United States
- Volunteers
- 17 people
- Sponsor
- Tocagen Inc.
Cutaneous Tumors
A Prospective Comparison of Suture Removal Time for Simple Surgical Defects of the Head and Neck
A single-center, prospective, randomized comparison with blinded assessment of cosmetic outcome. To compare cosmetic outcome of surgical defects of head and neck, repaired with non-resorbable monofilament sutures from the aspect…
- Trial name
- NCT02166996
- Testing
- Suture removal time 7 days, Suture removal time14 days
- Where
- Sweden
- Volunteers
- 116 people
- Sponsor
- Sundsvall Hospital
Non-surgical Retreatment
Effects of Different NiTi Systems on Postoperative Pain and Operation Time in Nonsurgical Endodontic Retreatment
This prospective, randomized, single-center, single-blind clinical trial evaluated the effects of different nickel-titanium retreatment and final shaping systems on postoperative pain and operation time during single-visit…
- Trial name
- NiTi-RETREAT (NCT07783945)
- Testing
- ProTaper Universal Retreatment System, MicroMega REMOVER, ProTaper Next
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Cataract
Retrospective Analysis of the Time Elements for Different Workflow Scenarios During Femtosecond Laser-assisted Cataract Surgery (FLACS) From the Surgeon, Staff, and Patient Perspectives.
This study involves the retrospecitve review of time stamps during surgery to assess the time efficiencies of different workflow scenarios of femtosecond laser-assisted cataract surgery from the surgeon, staff, and patient…
- Trial name
- NCT07038395
- Testing
- workflow
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- LensAR Incorporated
Postoperative Ileus
Electroacupuncture Combined With Fast-track Perioperative Program for Laparoscopic Colorectal Surgery
Background: The investigators' previous study demonstrated that electroacupuncture (EA) reduces the duration of postoperative ileus and hospital stay after laparoscopic colorectal surgery within a traditional perioperative care…
- Trial name
- NCT04090073
- Testing
- Electroacupuncture, Fast-track Perioperative program
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Chinese University of Hong Kong