Clinical trials: Duration of Response
AML
Real-Time Breath Analysis in Acute Myeloid Leukaemia for a Rapid Characterisation of Biological Subtypes and to Predict Therapy Responses
Patients with acute myeloid leukaemia (AML) respond to treatment to differing degrees, owing to the biological diversity of the disease.
- Trial name
- EXHALE (NCT07826897)
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Jeremy Deuel
Septic Shock, Weight, Body
Time to Lose the Weight? Comparison of Weight-based and Non-weight-based Vasopressors for Septic Shock
At present, there is conflicting evidence regarding outcomes in patients with septic shock receiving weight-based vasopressor (WBVP) versus non-weight-based vasopressor (NWBVP) dosing strategies.
- Trial name
- NCT04153578
- Where
- United States
- Volunteers
- 945 people
- Sponsor
- Methodist Health System
Breast Neoplasms
Tumor Response Time of Palbociclib in Combination With AI in Real-world Chinese Patients
The international treatment guidelines now include recommendations for the use of CDK 4/6 inhibitors in combination with hormone agents for the treatment of postmenopausal women with hormone-receptor-positive/HER2-negative ABC as…
- Trial name
- NCT04858997
- Testing
- Palbociclib, AI
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zhejiang Cancer Hospital
Measurement of Immune Response to Prevenar13, Measurement of Immune Response to Hepatitis A
PCV13 + Hepatitis A Vaccine for Adults
The present study explores whether a simultaneously given hepatitis A vaccine (Epaxal) will have an impact on the immune response to PCV13 (pneumococcal conjugate vaccine; Prevenar13) vaccine in adults.
- Trial name
- PCV13+HepA (NCT01926860)
- Testing
- Prevenar13, Hepatitis A vaccine
- Where
- 2 sites in Finland, Sweden
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Athletic Performance, Cognitive Fatigue
TCP-600 Supplementation and Performance Response in Professional Football Players
This study will examine whether a 28-day supplementation protocol containing taurine, caffeine, and phosphatidylserine can help professional male football players maintain physical performance, cognitive function…
- Conditions
- Athletic Performance, Cognitive Fatigue, Exercise Recovery, Football-Specific Performance
- Trial name
- TCP600-RESP (NCT07710547)
- Testing
- Taurine, Caffeine, Phosphatidylserine
- Where
- 3 sites in Poland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Vizja University in Warsaw
Rheumatoid Arthritis
Duration of Immune Response to Influenza Vaccination in Patients With RA
The main objective is to evaluate the strength and duration of immune response after influenza vaccination in patients with Rheumatoid Arthritis (RA) receiving treatment with biological agents as compared to a group healthy…
- Trial name
- NCT02311855
- Testing
- Influenza vaccine
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Bassett Healthcare
Chronic Hepatitis C
Hepatitis C Treatment Naive Genotype 1 Consensus Interferon Trial
Data have suggested that consensus interferon (CIFN) has greater antiviral activity in vitro compared with interferon alfa-2a or alfa-2b.
- Trial name
- NCT00211692
- Testing
- consensus interferon (Interferon Alfacon-1) and ribavirin, Consensus Interferon alfa (CIFN) and ribavirin
- Volunteers
- 64 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Adhd
The Day-time Response Variation of (Lis)Dexamphetamine
In the Netherlands, two forms of amphetamines are available for the treatment of ADHD in adults; dexamfetamine (Tentin) and lisdexamfetamine (Elvanse) and both belong to regular and primary care pharmacotherapy.
- Trial name
- IDEAL (NCT04946461)
- Testing
- Dexamfetamine Sulfate 5 Mg Oral Tablet, Lisdexamfetamine Dimesylate, blood samples
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Amsterdam UMC, location VUmc
Neonatal Neurobehavior
Effect of KMC on Neurobehavior of Preterm Neonates
This prospective cohort study was conducted on stable preterm infants (31 to 35 weeks gestation). Neonates were subjected to either daily KMC for 60 minutes, daily KMC for 120 minutes or conventional care (controls) for at least…
- Trial name
- NCT03740594
- Testing
- KMC
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Meningococcal Infection
Duration of hSBA Response After a Primary Series of Bivalent rLP2086 Followed by a Booster Dose
This study is to assess the longevity of immune response in adolescents for approximately 48 months after receipt of a primary series of bivalent rLP2086 vaccination, which is then followed by a booster dose and an assessment of…
- Trial name
- NCT01543087
- Testing
- blood sampling, bivalent rLP2086
- Where
- 56 sites in United States, Czechia and 4 more
- Volunteers
- 698 people, healthy volunteers welcome
- Sponsor
- Pfizer
Obesity
Anti-psychotic Medication (New Use) Weight Loss Study
This is a pilot study to determine the safety and efficacy of an investigational product (IHBG-10) on weight change and changes in body composition in subjects who have just started taking (for less than three months) certain…
- Trial name
- NCT01272752
- Testing
- IHBG-10
- Where
- United States
- Sponsor
- Avera McKennan Hospital & University Health Center
Consumer Behavior, Consumer Preference
Impact of Chip Thickness and Size on Eating Responses
To analyze prototypes developed with the base and seasonings of products that exhibit variations in chip thickness and size. The information obtained from this analysis will serve as the basis for subsequent research to explore…
- Conditions
- Consumer Behavior, Consumer Preference, Consumer Satisfaction
- Trial name
- NCT06691958
- Testing
- Tortilla corn chips 4-5 pieces, eat one piece at time, Tortilla corn chips 90 grams, Extruded corn chips 90 grams
- Where
- United Kingdom
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Herpes Zoster
A Study on the Immune Response and Safety of the Shingles Vaccine and the Influenza Vaccine When Either is Given to Healthy Adults at the Same Time or Following a COVID-19 Booster Vaccine
The aim of this study was to evaluate the immune response and safety of both GlaxoSmithKline Biologicals SA's (GSK's) herpes zoster (HZ) subunit (su) vaccine in healthy adults 50 years of age (YOA) and older and quadrivalent…
- Trial name
- NCT05047770
- Testing
- HZ/su, Flu D-QIV, mRNA-1273
- Where
- 46 sites in United States
- Volunteers
- 2,013 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Plaque Psoriasis
Multiple-loading Dose Regimen Study in Patients With Chronic Plaque-type Psoriasis
Loading dose, four arm, double-blind, parallel group, placebo-controlled study comparing single and multiple doses of AIN457 to placebo in patients with a diagnosis of moderate to severe chronic plaque psoriasis.
- Trial name
- NCT00805480
- Testing
- AIN457
- Volunteers
- 130 people
- Sponsor
- Novartis Pharmaceuticals
Stroke
"Mobile Stroke-Unit" for Reduction of the Response Time in Ischemic Stroke
Stroke, the most common cause of permanent disability, the second most common cause of dementia and third most common cause of death, has tremendous socio-economic consequences.
- Trial name
- MSU (NCT00792220)
- Testing
- MSU, OCCM
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Saarland
Alzheimer Disease and Related Dementias, Cognition
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function…
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Trial name
- TDCS4MCR (NCT06821568)
- Testing
- Personalized Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 128 people
- Sponsor
- Hebrew SeniorLife
Metastatic Renal Cell Carcinoma
A Retrospective Real World Analysis Of Sutent In Patients With Metastatic Renal Cell Carcinoma In Community And Academic Centers To Assess The Impact Of Dose Variation On Duration Of Response And Overall Survival
This is a retrospective, non-interventional study which looks at the cohort of Renal Cell Carcinoma patients in a real life clinical setting and analyses into factors why these patients have been surviving for as long as 3-5…
- Trial name
- NCT01917214
- Testing
- Sutent: Observational Study
- Volunteers
- 212 people
- Sponsor
- Pfizer
Breast Cancer
Contrast Enhanced Ultrasound and Shear Wave Elastography in Measuring Response in Patients With Breast Cancer Receiving Chemotherapy Before Surgery
This pilot clinical trial studies contrast enhanced ultrasound and shear wave elastography in measuring response in patients with breast cancer receiving chemotherapy before surgery.
- Trial name
- NCT02067884
- Testing
- dynamic contrast-enhanced ultrasound imaging, shear wave elastography, Definity, (Lipid Microspheres) Intravenous Suspension
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Southern California
Obesity, Diabetes Mellitus, Type 2
This Study Assessed the Impact of Diet on Gastric Emptying Time and Metabolic Flexibility
Consumption of slowly digestible carbohydrates can elicit higher satiety feeling compared to rapidly digestible carbohydrates, however not all individuals respond the same.
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Appetitive Behavior
- Trial name
- IODC (NCT03630263)
- Testing
- Raw Corn Starch, No Raw Corn Starch
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Purdue University
Vaccines, Meningococcal Vaccines
A Clinical Trial to Study the Safety, Tolerance and Immunogenic Response to Gardasil and Bivalent rLP2086 Vaccine When Given at the Same Time to Children Between the Ages of 11 and 17
This is a clinical study to assess the safety, tolerance and immunogenic response to Gardasil (human papilloma virus (HPV)) and rLP2086 vaccine.
- Trial name
- NCT01461993
- Testing
- rLP2086 and Gardasil, rLP2086, Gardasil
- Where
- 87 sites in United States
- Volunteers
- 2,499 people, healthy volunteers welcome
- Sponsor
- Pfizer