Clinical trials: Duration of Response
Bacteremia
T2 and SeptiCyte RAPID Duration Project
Infection with bacteria and other germs in the blood can be deadly. How long germs stay in the blood is important for two reasons.
- Trial name
- NCT04821661
- Where
- 3 sites in Australia
- Volunteers
- 102 people
- Sponsor
- The University of Queensland
Diffuse Large B-cell Lymphoma
A Study to Evaluate Lenalidomide Combined With Dexamethasone in Relapsed or Refractory Diffuse Large B-Cell Lymphoma
To evaluate the safety and efficacy of lenalidomide (Revlimid ®) in combination with dexamethasone in subjects with relapsed or refractory diffuse large B-cell lymphoma.
- Trial name
- NCT00474188
- Testing
- CC-5013 (lenalidomide), dexamethasone
- Where
- 24 sites in United States, Australia and 1 more
- Volunteers
- 26 people
- Sponsor
- Celgene Corporation
Exercise, Fatigue
Physiological Responses to Basketball-Specific Interval Exercise in Female Basketball Players
This study aims to evaluate the effects of interval exercise on metabolic and inflammatory responses, energy substrate utilization, and fatigue in trained female basketball players.
- Conditions
- Exercise, Fatigue, Sport Physiology
- Trial name
- INTER-BASKET (NCT07752459)
- Testing
- Yo-Yo Intermittent Recovery Test Level 1 (Yo-Yo IR1)
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Moderate and Severe Plaque Psoriasis
A Dose Finding Study of AEB071 Assessing Psoriasis Area and Severity Index in Patients With Plaque Psoriasis
This study is designed to provide efficacy and safety data of several doses of AEB071 so that the optimal dose and treatment duration can be chosen for testing in later studies in patients with plaque psoriasis (with a disease…
- Trial name
- NCT00885196
- Testing
- AEB071
- Where
- 40 sites in United States, Argentina and 7 more
- Volunteers
- 336 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure
Reduction or Extension of COnduction Time With Ventricular Electromechanical Remodeling (RECOVER)
This prospective multicenter registry study aims to detect the serial changes in ventriculo-ventricular conduction times according to cardiac-resynchronization therapy response.
- Trial name
- RECOVER (NCT04397224)
- Testing
- Device interrogation
- Where
- 6 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Physiological Responses to High-Intensity Exercise
Effects of the Q-Collar During High-Intensity Cycling Exercise
This study examined the effects of wearing the Q-Collar during high-intensity cycling exercise. Eleven recreationally trained male participants completed two 5-kilometer cycling time trials: one while wearing the Q-Collar and one…
- Trial name
- NCT07808710
- Testing
- Q-Collar™
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Infection Systemic
Duration of Antibiotic Therapy in Critically Ill Patients: C-reactive Protein-guided Therapy Versus Best Practice
The judicious use of antibiotics is one of the main measures to limit the emergence of multidrug-resistant pathogen related to excessive antimicrobial use.
- Trial name
- NCT02987790
- Testing
- C-reactive protein
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Federal University of Minas Gerais
Glucose, Metabolism
Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells - Intensive Care Unit
The purpose of this study is to understand how cells of the immune system use the common sugar glucose during critical illness. Investigators will intravenously infuse a non-radioactive carbon-13 glucose tracer into adult…
- Conditions
- Glucose, Metabolism, Isotope Labeling, Immune System and Related Disorders
- Trial name
- TORCH-ICU (NCT07811180)
- Testing
- 13C6-Glucose
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Vanderbilt University Medical Center
Mental Fatigue
The Effect of a Caffeine Blend on Reaction Time, Mental Performance and Focus in Athletic Males
This is a cross-over design study in which subjects arrived to the lab and were assigned a supplement to ingest. Prior to ingestion subjects completed baseline reaction time testing along with a questionnaire.
- Trial name
- NCT03019523
- Testing
- Caffeine Blend, Sugar Pill
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Mary Hardin-Baylor
Healthy
Bioavailability of Hydroxytyrosol in Healthy Adult Humans
Brief summary: There is current scientific interest in hydroxytyrosol due to its anti-inflammatory and antioxidant properties, efficient protection of vascular tissue and ability to neutralise free radicals via hydrogen donation.
- Trial name
- NCT06285682
- Testing
- OliPhenolia®)
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Low Back Pain, Vertebrogenic Pain Syndrome
Time to BBVNA Relief
Basivertebral nerve ablation (BVNA) is a minimally invasive procedure approved for vertebrogenic low back pain. While early studies support its efficacy, real-world evidence is still evolving, particularly regarding the…
- Conditions
- Low Back Pain, Vertebrogenic Pain Syndrome, Basivertebral Nerve Ablation
- Trial name
- NCT07433634
- Testing
- Basivertebral nerve ablation
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Yale University
Typhoid Fever
Safety and Immunogenicity of a Novel Conjugate Vaccine Against Salmonella Typhi and Salmonella Paratyphi A in Healthy Adults
A bivalent Typhoid and Paratyphoid A conjugate investigational vaccine aimed to prevent both typhoid and paratyphoid enteric fever in infants and older age groups has been developed by GlaxoSmithKline (GSK).
- Trial name
- NCT05613205
- Testing
- TYP04A Low Dose without Alum investigational vaccine, TYP04B Full Dose without Alum investigational vaccine, TYP03A Low Dose with Alum investigational vaccine
- Where
- Belgium
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Parkinson's Disease
12-Week, Double-Blind, Placebo-Controlled, Randomized Study of the Efficacy of 40 mg/Day KW-6002 in Parkinson's Disease Patients on Levodopa/Carbidopa
12-week, double-blind, placebo-controlled, multicenter, randomized study designed to evaluate the safety and efficacy of 40 mg/day istradefylline compared with placebo in subjects with OFF phenomena advanced PD who were treated…
- Trial name
- NCT00456586
- Testing
- KW-6002 (istradefylline)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Kyowa Kirin, Inc.
Glabellar Frown Lines
Duration of Botox Using OLD Versus COLD for Treatment of Glabellar Lines
This is a blinded, randomized study in the US to compare the duration response of two different concentrations of BOTOX in healthy female subjects with moderate to severe dynamic glabellar lines on maximum frown.
- Trial name
- NCT05083286
- Testing
- OnabotulinumtoxinA
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinical Testing of Beverly Hills
Gastric Cancer
Sorafenib as a Second Line Treatment in Patients With Advanced or Metastatic Gastric Cancer
The purpose of this study is to evaluate the efficacy and tolerability of sorafenib as second line treatment in patients with Advanced or Metastatic Gastric Cancer (A/MGC).
- Trial name
- NCT00595985
- Testing
- sorafenib
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Fudan University
Diabetes Mellitus, Type 2, Circadian Rhythm
Circadian Rhythm and Metabolic Effects of Exercise
Physical exercise is efficacious in controlling blood glucose levels in individuals with Type 2 diabetes. An individual's exercise capacity and ability to utilize glucose as an energy source oscillates throughout the day.
- Conditions
- Diabetes Mellitus, Type 2, Circadian Rhythm, Glycemic Control
- Trial name
- HITMet (NCT05115682)
- Testing
- High-intensity Intermittent Exercise
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Premature Infant, Pain
The Effect of Breast Milk Odor on Pain Response and Salivary Cortisol Level in Preterm Infants
The aims of this randomized controlled trial are investigate the effects of breast milk odor on pain response and saliva cortisol level duration heel stick blood sampling in preterm infants.
- Conditions
- Premature Infant, Pain, Breast Milk Odor
- Trial name
- NCT05557435
- Testing
- breast milk odor
- Volunteers
- 64 people
- Sponsor
- Taipei Medical University
Laryngoscopy, Stress Response
Comparison of Stress Response Evoked by Conventional Versus Videolaryngoscope
Impact of using video laryngoscopy versus direct laryngoscopy technique in terms of improved hemodynamics post intubation and time taken for intubation.
- Conditions
- Laryngoscopy, Stress Response, Duration
- Trial name
- NCT07510542
- Testing
- Endotracheal Intubation through a Video Laryngoscope (VL), Endotracheal Intubation through a Direct Laryngoscope (DL)
- Where
- Pakistan
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation
Cerebral Palsy
WittyChildren - Advanced Technology for Response Time Evaluation in Children Affected by Developmental Disorders
The WittyChildren project aims to evaluate the response to visual stimuli in terms of reaction times and movement execution using advanced instruments.
- Trial name
- NCT07240740
- Testing
- The WittySEM system, in addition to simultaneously allowing the evaluation of the movement associated with the execution of the task, also provides for an active and "play-like" involvement of the sub
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Eugenio Medea
Colorectal Neoplasms
Phase 2 Study With Abraxane (Nab®Paclitaxel) in Metastatic Colorectal Cancer
The purpose of this study is to evaluate the safety and efficacy of Abraxane (nab-paclitaxel) in subjects with previously treated metastatic colorectal cancer.
- Trial name
- NCT02103062
- Testing
- ABI-007
- Where
- 6 sites in France
- Volunteers
- 41 people
- Sponsor
- Celgene