Clinical trials: Dynamic Arterial Elastance
Critical Illness, Fluid Over-load
Effect of Dynamic Arterial Elastance and Assisted Fluid Management Software Guided Resuscitation in Septic Shock: Pilot Study
To investigate the benefit of using the AFM and Eadyn-guided fluid and vasopressor therapy in septic shock resuscitation for mechanically ventilated patients compared with the standard of care.
- Conditions
- Critical Illness, Fluid Over-load, Dynamic Arterial Elastance, Septic Shock
- Trial name
- DAFM shock (NCT06937918)
- Testing
- The AFM and Eadyn - guided resuscitation group, The standard care for septic shock
- Where
- 3 sites in Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Septic Shock
Evaluating Dynamic Arterial Elastance in Septic Shock Patients.
Assess the effectiveness and safety of using dynamic arterial elastance as a tool for weaning vasopressor support in patients with septic shock, compared to a control group
- Trial name
- EaDyn (NCT06118775)
- Testing
- EaDyn Weaning Arm:, PAM Weaning Arm:
- Where
- Colombia
- Volunteers
- 114 people
- Sponsor
- Fundación Santa Fe de Bogota
Arterial Disease
Dynamic Arterial Elastance: an Indirect Marker of the Critical Capillary Pressure at the Microcirculatory Level
The measurement of dynamic arterial elastance (Eadyn) was proposed as a marker of vascular tone. It is calculated by the ratio of the respiratory variation of the pulse pressure and the respiratory variation of stroke volume.
- Trial name
- POEME (NCT03478709)
- Testing
- volume expansion, norepinephrine
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hypovolemia
Assessment of Arterial Dynamic Elastance as a Function Variable of Arterial Load
The goal of the study is to determine Eadyn as a functional measure of arterial load, in conjunction with other actual afterload indices, derived from both invasive arterial pressure tracing and non-invasive signals, such as…
- Trial name
- Eadyn (NCT02774304)
- Testing
- arterial line, Cheetah®
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitair Ziekenhuis Brussel
Sepsis, Cardiac Failure Acute
Clinical Assessment of Arterial Dynamic Elastance in ICU Patients, Dependent on Inotropic or Vasopressor Drugs.
The primary goal of the study is to determine Eadyn ( = PPV/SVV) as a functional measure of arterial load, in conjunction with other actual afterload indices, systemic vascular resistance and arterial elastance.
- Trial name
- NCT03621618
- Testing
- dobutamine, norepinephrine
- Where
- Belgium
- Sponsor
- Universitair Ziekenhuis Brussel
Anesthesia
Dynamic Arterial Elastance During General Anesthesia Induction
This study evaluates if dynamic arterial elastance measured before general anesthesia induction can predict the occurrence of hypotension due to general anesthesia induction.
- Trial name
- NCT03910179
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Università Politecnica delle Marche
Sepsis
Dynamic Arterial Elastance as a Predictor of Arterial Blood Pressure Response to Fluid Administration in Septic Patients
Correction of arterial hypotension is essential for adequate cellular metabolism. maintaining MAP above a minimum level has been recommended in order to prevent further tissue hypoperfusion and organ dysfunction.Functional…
- Trial name
- NCT03179215
- Testing
- fluid challange
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Hypotension
Dynamic Arterial Elastance to Predict Postural Change Induced Hypotension
During general anesthesia, hypotension might occur during positional change. It is reported that hypotension after positional change from supine to prone is mainly caused by the decrease in preload.
- Trial name
- NCT04850092
- Testing
- Positional change from supine to prone
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Kangbuk Samsung Hospital
Coronary Artery Disease
Dynamic Arterial Elastance for Prediction of Vasopressor Requirement After Anesthesia Induction in Elective On-Pump CABG
This study aims to determine whether dynamic arterial elastance (EaDyn), measured after anesthesia induction, can predict the need for vasopressor treatment in patients undergoing elective on-pump coronary artery bypass graft…
- Trial name
- NCT07871201
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Elzem SEN
Vasoplegia Syndrome
Dynamic Arterial Elastance Measured by Uncalibrated Pulse Contour Analysis Predicts Arterial Pressure Response to a Decrease in Norepinephrine
Dynamic arterial elastance (Eadyn) has been proposed as an indicator of arterial tone that can predict norepinephrine-dependent arterial pressure.
- Trial name
- VESA (NCT03455738)
- Testing
- vasoplegic syndrome
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens