Clinical trials: Dysesthesia
Thoracic Surgery
Sensory Changes Associated With Thoracic Surgery
Many patients experience chronic pain after thoracic surgery and this is caused by nerve damage during surgery. Changes in skin sensation (dysaesthesia) is typically associated with chronic nerve pain.
- Trial name
- NCT06420570
- Testing
- Thoracic Surgery
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Edinburgh
Paresthesia, Dysesthesia
Sensory Mapping Following Video-assisted Thoracic Surgery
This is a prospective observational cohort study on changes in sensory mapping.
- Conditions
- Paresthesia, Dysesthesia, Pain
- Trial name
- NCT01375283
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sciatica, Radiating Pain
The Effect of Early MSAT Treatment on Sciatica Caused by Traffic Accidents.
The investigators would like to conduct a pilot study prior to a practical randomized control study on the effectiveness of initial MSAT treatment on inpatients complaining of radiating pain and abnormal sensation in the lower…
- Conditions
- Sciatica, Radiating Pain, Paresthesia, Dysesthesia
- Trial name
- NCT06179901
- Testing
- Integrative Korean Medicine Treatment, lower limb motion style acupuncture treatment
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jaseng Medical Foundation
Head and Neck Neoplasms, Dysesthesia
Prospective Analysis of Effect of Collagen Wrap Conduit on Radial and Ulnar Nerve Function Following Radial/Ulnar Forearm Free Flap Harvest
The purpose of this study is to determine whether collagen nerve conduits placed on exposed radial and ulnar nerves during radial and ulnar forearm free flap harvests will reduce the occurrence and degree of sensory nerve deficit.
- Trial name
- NCT03875833
- Testing
- Collagen Nerve Wrap Conduit
- Sponsor
- The University of Texas Health Science Center, Houston
Persistent Genital Arousal Disorder
Examining the Effectiveness of a Group Cognitive-behavioural Treatment Program for Persistent Genital Arousal Disorder
This study seeks to provide information regarding the effectiveness of a virtual, synchronous cognitive behavioural therapy (CBT) group program for women with Persistent Genital Arousal Disorder/Genitopelvic Dysesthesia…
- Trial name
- NCT05919784
- Testing
- Cognitive behavioural therapy
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Dr. Caroline Pukall
CIPN - Chemotherapy-Induced Peripheral Neuropathy
Internet-delivered Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN)
This is a small pilot trial (n=26) among cancer survivors with CIPN who will utilize an internet-delivered pain coping program for 8 weeks in order to assess program feasibility and preliminary understanding of how participation…
- Trial name
- NCT05556447
- Testing
- Internet delivered pain coping skills training
- Sponsor
- Wake Forest University Health Sciences
Stomatitis, Pain
MucoLock™ for Treatment of Stomatitis
The purpose of this research is to test how well people can tolerate MucoLock™ as a treatment for mouth pain or burning sensation and how well it works to reduce mouth pain or burning sensation.
- Conditions
- Stomatitis, Pain, Burning Mouth, Burning Mouth Syndrome
- Trial name
- NCT07506018
- Testing
- MucoLock Oral Gel
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Baptist Health South Florida
Distal Amputation of the Fingers
Lipofilling Versus Conservative Treatment in Fingertips Injuries Sequelae
The purpose of this study is to evaluate the contribution of autologous graft reinjection (lipofilling) in the treatment of dysaesthesic pulp.
- Trial name
- LIPOFILLING (NCT04076397)
- Testing
- autologous transplant reinjection, desensitization
- Where
- 2 sites in France
- Sponsor
- University Hospital, Brest
Neuropathy, Digestive Cancer System
Prevention of Oxaliplatin-induced Neuropathic Pain by a Specific Diet
Use lay language. Oxaliplatin is a reference anticancer drug in the treatment of colorectal cancer. However, its use is hampered by a specific neurotoxicity, which is characterized by acute thermal hypersensitivity, notably to…
- Trial name
- NEUROXAPOL (NCT01775449)
- Testing
- Polyamines depleted diet, associating Polydol® cans and predefined menus low in polyamines
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Atopic Dermatitis
Tolerance and Efficacy Open-label Study With RV4421B, in Various Populations With Atopic Dermatitis for 12 Weeks
Pierre Fabre Laboratories have developed a cream with medical device status, RV4421B-EV0407 indicated for the treatment of eczemas, including atopic eczema, contact eczema and chronic hand eczema.
- Trial name
- NCT07014007
- Testing
- RV4421B- EV0407
- Where
- Mauritius
- Volunteers
- 105 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain
Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)
Peripheral neuropathy is a disorder caused by damage to the peripheral nerves. Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of certain chemotherapy drugs, such as platinum-based compounds, taxanes…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Peripheral Neuropathic Pain
- Trial name
- NCT07072468
- Testing
- VMD-3866 Gel
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- VM Therapeutics LLC
Pain, Diabetic Neuropathies
A Research Study of V3381 for the Treatment of Diabetic Peripheral Neuropathic Pain
The objective of this study is to investigate the safety and efficacy of an investigational drug, V3381, for the treatment of diabetic peripheral neuropathic (DPN) pain (pain in one's feet and legs, or even in one's hands and…
- Trial name
- NCT00375960
- Testing
- V3381
- Where
- 6 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- Vernalis (R&D) Ltd
Oral Submucous Fibrosis
Alternating Triamcinolone and Platelet-Rich Plasma Therapy for Oral Submucous Fibrosis
Oral Submucous Fibrosis (OSF) is a chronic, progressive, potentially malignant disorder characterized by mucosal stiffness, trismus, and burning sensation.
- Trial name
- RegenOSF (NCT07277998)
- Testing
- Platelet-Rich Plasma (PRP) Injections, Triamcinolone Acetonide
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Karachi Medical and Dental College
Mucositis, Dry Mouth
Effect of Fluoride Varnish and CPP-ACP on Oral and Salivary Symptoms During Chemotherapy
The purpose of this study was to investigate the effect of Fluoride varnish and Casein Phospho-Peptide Amorphous Calcium Phosphate (CPP-ACP) containing paste on oral symptoms and salivary characteristics in patients under…
- Conditions
- Mucositis, Dry Mouth, Infection
- Trial name
- NCT01737307
- Testing
- Fluoride varnish, Oral Hygiene, CPP-ACP
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Azad University of Medical Sciences
Ischemic Cardiopathy, Other Forms of Cardiopathy
Dysesthesia Study After Sternotomy
Chronic pain associated to sternotomy occurs in 40 to 50% of patients after cardiac surgery. 33 to 66% of these patients suffer during 3 month and 25 to 33% have postoperative pain for at least 1 year.
- Trial name
- NCT00408044
- Testing
- cardiac surgery with sternotomy
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Burning Mouth Syndrome
Reducing Patient Memory Recall in the Burning Mouth Patient Population
The goal of this study is to learn about burning mouth syndrome symptoms in real time in patients with burning mouth syndrome. The main questions it aims to answer are: (1) To test the ability of a smartphone app to collect…
- Trial name
- NCT05819697
- Testing
- FIRE Trial/Track Your Happiness notifications
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Restless Leg Syndrome
Investigation of Efficacy of incobotulinumtoxinA (Xeomin) in Relieving Symptoms of Restless Leg Syndrome.
The purpose of this research study is to compare the safety and effectiveness of local injections of botulinum toxin A (Xeomin®) to an inactive test substance (placebo) in a medical condition called Restless Leg Syndrome.
- Trial name
- NCT01931878
- Testing
- incobotulinumtoxinA
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Oral Submucous Fibrosis
Curcumin Plus Topical Steroid Versus Topical Steroid Alone for Oral Submucous Fibrosis
This study evaluates whether combining oral curcumin (a natural compound derived from turmeric) with a topical steroid is more effective than using a topical steroid alone in treating Oral Submucous Fibrosis (OSMF).
- Trial name
- NCT07891130
- Testing
- Curcumin and and triamcinolone acetonide, Triamcinolone Acetonide
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat College of Medicine and Dentistry