Clinical trials: Dysfunctional Central Venous Access Devices (CVADS)
Restoration of Function to CVADs
Efficacy and Safety of CUSA-081 in the Restoration of Dysfunctional Central Venous Access Device (CVAD) Functionality
Study to evaluate the efficacy and safety of CUSA-081 in the restoration of central venous access device (CVAD) functionality in participants 12 years and older.
- Trial name
- READY 2 (NCT03992443)
- Testing
- CUSA-081
- Where
- 15 sites in United States, Bulgaria and 1 more
- Sponsor
- Chiesi Farmaceutici S.p.A.
Dysfunctional Central Venous Access Devices (CVADS)
Cathflo Activase Pediatric Study
This was a Phase IV, open-label, single-arm, multicenter trial that was to be conducted at ~60 sites in the United States. Approximately 300 pediatric subjects with dysfunctional CVADs (including catheters with valves, multiple…
- Trial name
- NCT00307580
- Testing
- Cathflo Activase (Alteplase)
- Volunteers
- 300 people
- Sponsor
- Genentech, Inc.
Catheter Occlusion, Thrombosis
Efficacy and Safety of CUSA-081 in the Restoration of Central Venous Access Device (CVAD) Functionality
To evaluate the efficacy and safety of CUSA-081 (diluted reteplase) in the restoration of central venous access device (CVAD) functionality in participants 18 years and older.
- Trial name
- READY1 (NCT03594175)
- Testing
- CUSA-081, Alteplase
- Where
- 77 sites in United States, Argentina and 5 more
- Volunteers
- 462 people
- Sponsor
- Chiesi Farmaceutici S.p.A.