Clinical trials: Dysglycaemia
Gestational Diabetes
EARLY Pregnancy GLucose prOfiles in Women With and Without GDM Risk Factors: EARLY-GLOW
Background: Gestational diabetes mellitus (GDM) is associated with increased maternal and neonatal complications, including macrosomia, preeclampsia, and long-term metabolic consequences for both mother and child.
- Trial name
- EARLY-GLOW (NCT07783178)
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- DCB Research AG
Dysglycaemia
Achieving Normal Glucose In Hospital Settings
The main objective of this study is to evaluate the efficacy and safety of 24 hours of closed-loop glucose control compared with standard diabetes treatment, in patients with type 2 diabetes treated by non-insulin…
- Trial name
- Angie01 (NCT01359241)
- Testing
- closed-loop insulin delivery, Usual diabetes treatment regimen
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Cambridge
Diabetes Type 2
Effects of Different Doses of Aspirin on Pathophysiological Markers in Type 2 Diabetes
This study was set up to assess the effects of different doses of aspirin when compared with placebo (dummy drug), used sequentially over a 2 week study period with a 2 week wash-out (rest period) in between, in people with…
- Trial name
- NCT00898950
- Testing
- Aspirin
- Where
- 2 sites in United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Metabolic Syndrome, Pre-diabetes
Effect of Pasteurized Akkermansia Muciniphila on Insulin Resistance in Otherwise Healthy Subjects With Dysglycaemia
The purpose of this study is to demonstrate the efficacy of pasteurized Akkermansia muciniphila (pAKK) in improving insulin sensitivity in hyperglycaemic, but otherwise healthy persons with metabolic syndrome.
- Conditions
- Metabolic Syndrome, Pre-diabetes, Overweight and Obesity
- Trial name
- NCT05114018
- Testing
- Pasteurized A. muciniphila
- Where
- 2 sites in Germany, Ireland
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- A-Mansia Biotech S.A.
Gestational Diabetes Mellitus (GDM), GDM
Hong Kong Gestational Diabetes Register (HKGDR)
Gestational diabetes mellitus (GDM) is a common condition that affects approximately one out of every six pregnancies. It is defined by elevated levels of blood glucose during pregnancy, usually detected through a glucose…
- Trial name
- NCT07271407
- Where
- Hong Kong
- Volunteers
- 2,000 people
- Sponsor
- Chinese University of Hong Kong
Diabetes
Identification and Characterization of Diabetes in Low-resource Populations
The true burden of diabetes in sub-Saharan Africa (SSA) is unknown as most of the countries do not have good quality data. As such, the overall estimate of diabetes prevalence is largely based on modelled estimates, which may not…
- Trial name
- DOP (NCT05487079)
- Where
- Uganda
- Volunteers
- 11,700 people
- Sponsor
- MRC/UVRI and LSHTM Uganda Research Unit
Cystic Fibrosis, Cystic Fibrosis-related Diabetes
A CFit Study - Acute Exercise
A great medical success is the increase in the median survival age associated with cystic fibrosis (CF). However, this success has led to a new era of research aiming to maximise the quality of life (QoL) of the aging CF…
- Trial name
- NCT03237767
- Testing
- MIE, HIIE
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- University of Portsmouth
Severe Mental Disorder, Diabetes Mellitus
Electronic Clinical Decision Support for Diabetes and Dysglycaemia in Secondary Mental Healthcare
People with serious mental illness (SMI) such as schizophrenia, schizoaffective disorder and bipolar affective disorder have a significantly reduced life expectancy, caused in part by increased incidences of mortality from…
- Conditions
- Severe Mental Disorder, Diabetes Mellitus, Dysglycemia, Staff Attitude
- Trial name
- NCT04792268
- Testing
- Access to eCDSS on wards
- Where
- United Kingdom
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- King's College London
Diabetes Mellitus, Affective Disorders
Depression and Diabetes Control Trial
This randomised controlled trial evaluates a cognitive-behavioural intervention for diabetes patients with suboptimal glycaemic control and comorbid depressive symptoms and/or diabetes distress.
- Conditions
- Diabetes Mellitus, Affective Disorders, Depression, Depressive Symptoms
- Trial name
- DDCT (NCT02675257)
- Testing
- Diabetes-related affective problems analysis, Goal setting towards improvement of glycaemic control, Diabetes-specific problem-solving therapy
- Where
- 2 sites in Germany
- Volunteers
- 213 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Diabetes Mellitus, Type 2, Heart Diseases
The Effects of an 8-week Vegan Diet on TMAO Levels and Post-challenge Glucose Levels in Individuals With Dysglycaemia
The amount of people with diabetes mellitus has now reached over 4 million in the United Kingdom. Type 2 diabetes accounts for the majority of all cases of diabetes and increases the risk of many other diseases such as heart…
- Trial name
- PYH (NCT03315988)
- Testing
- Adoption of a vegan diet
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- University of Leicester