Clinical trials: Dyslipidemia Associated With Type II Diabetes Mellitus
Diabetes Mellitus
Efficacy and Safety of Pioglitazone in Treating Subjects With Vascular Complications Associated With Type 2 Diabetes Mellitus.
The purpose of this study is to determine the efficacy of pioglitazone compared to glibenclamide, once daily (QD), taken together with metformin and lifestyle modification in type 2 diabetic subjects with cardiovascular disease.
- Trial name
- SPLENDOR (NCT00770835)
- Testing
- Pioglitazone and Metformin, Glibenclamide and Metformin
- Where
- 2 sites in Italy
- Volunteers
- 39 people
- Sponsor
- Takeda
Dyslipidemia Associated With Type II Diabetes Mellitus
Moderate-intensity Statin vs. Individualized LDL-C Target-based Therapy in Older Adults With Type 2 Diabetes (iTARGET-Elderly Study)
Statins are the cornerstone of cardiovascular disease (CVD) prevention through the lowering of low-density lipoprotein cholesterol (LDL-C).
- Trial name
- NCT07359105
- Testing
- Moderate-intensity statin monotherapy, Ezetimibe or ezetimibe-statin combination therapy
- Where
- 2 sites in South Korea
- Volunteers
- 2,186 people
- Sponsor
- Sin Gon Kim
Dyslipidemia Associated With Type II Diabetes Mellitus
Effectiveness of Nutritional Program Among Diabetic Patients
Dyslipidemia is very common in type 2 diabetes mellitus affecting around 72%-85% of diabetic patients.The exact mechanism of lipoprotein abnormalities in diabetes is not very well understood.
- Trial name
- NCT05128747
- Testing
- DASH diet
- Volunteers
- 190 people
- Sponsor
- Assiut University
Type 2 Diabetes, Insulin Resistance
Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin Resistance
The objective of this study is to determine whether targeted pharmacological improvement of insulin sensitivity will normalize the associated elevations of thrombotic and inflammatory cardiovascular disease (CVD) biomarkers in…
- Conditions
- Type 2 Diabetes, Insulin Resistance, Metabolic Syndrome
- Trial name
- NCT00443755
- Testing
- metformin, pioglitazone
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Mayo Clinic
Sexual Dysfunction
Statin Lowering Testosterone and Sexual Function
Statins may decrease serum testosterone levels via decreasing cholesterol. This longitudinal study detected the effects of rosuvastatin on free testosterone levels and sexual function in men with type 2 diabetes.
- Trial name
- NCT02612714
- Testing
- Rosuvastatin
- Where
- Taiwan
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Dyslipidemia Associated With Type II Diabetes Mellitus
An Observational Study Investigating the Effectiveness of Pravastatin on Renal Function in Korean Dyslipidemic Patients With Type 2 Diabetes
This study investigated the effectiveness of pravastatin on renal function in Korean dyslipidemic patients with Type 2 diabetes.
- Trial name
- NCT05107063
- Testing
- Pravastatin
- Where
- 47 sites in South Korea
- Volunteers
- 2,972 people
- Sponsor
- Daiichi Sankyo
Dyslipidemia Associated With Type II Diabetes Mellitus, Diabetes Mellitus, Type 2
EXpanded Combination of Evolocumab Plus Empagliflozin on Diabetes: EXCEED-BHS3 Trial
Based on the current evidence, empagliflozin could reduce cardiovascular morbidity and mortality in Diabetes Mellitus Type 2 (T2DM).
- Conditions
- Dyslipidemia Associated With Type II Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension Arterial
- Trial name
- EXCEED-BHS3 (NCT03932721)
- Testing
- Evolocumab 140 MG/ML
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- University of Campinas, Brazil
Diabetes Mellitus, Type 2, Overweight and Obesity
Dietary Strategies for Remission of Type 2 Diabetes
In this project, the investigators will perform a multicenter randomised controlled trial to determine whether advice to consume a moderate, whole food-based low-carbohydrate high-fat (LCHF) ad libitum diet (CarbCount program)…
- Conditions
- Diabetes Mellitus, Type 2, Overweight and Obesity, Hypertension, Glucose Intolerance
- Trial name
- CARBCOUNT (NCT04943926)
- Testing
- Energy restricted diet, Low carbohydrate high fat diet
- Where
- Norway
- Volunteers
- 600 people
- Sponsor
- University of Bergen
Diabetes Mellitus, Type 2, Liver Fibrosis
Effect of an Early Time Restricted Eating Mediterranean Diet Compared to Naltrexone/Bupropion on Liver Fibrosis in People With Cardiometabolic Risk Factors in a Hospital Outpatient Clinic (MEDFAST-study)
In the Netherlands, there are many people with cardiometabolic diseases. More than half of these people also have fatty liver. This is a build-up of fat in the liver (steatosis) and can lead to long-term scarring (fibrosis) and…
- Conditions
- Diabetes Mellitus, Type 2, Liver Fibrosis, Liver Steatoses, Hepatic Steatosis
- Trial name
- MEDFAST (NCT06845345)
- Testing
- early time restricted Mediterranean diet, Mysimba
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Carmen Dietvorst
Dyslipidemia Associated With Type II Diabetes Mellitus
Efficacy and Safety of Berlim 25/20 Association in the Treatment of Type II Diabetes Mellitus and Dyslipidemia.
The purpose of this study is to evaluate the efficacy and safety of Berlim 25/20 association in the treatment of type 2 diabetes mellitus and dyslipidemia.
- Trial name
- NCT04602754
- Testing
- BERLIM 25/20 ASSOCIATION, EMPAGLIFLOZIN, ROSUVASTATIN CALCIUM
- Where
- Brazil
- Volunteers
- 228 people
- Sponsor
- EMS
Type 2 Diabetes Mellitus in Obese, Dyslipidemia Associated With Type II Diabetes Mellitus
Type 2 Diabetes Mellitus With Obesity and Dyslipidemia Treated by Chinese Herbal Medicine
This study is a retrospective review of participants who visited Department of Endocrinology, Guang'anmen Hospital and accepted traditional Chinese medicine formula for at least sis months, from January 2015 to December 2020.
- Trial name
- NCT05072990
- Testing
- Chinese herb medicine
- Where
- China
- Volunteers
- 95 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Diabete Mellitus, Pre-diabetes
Investigating the Syndrome Differentiation of Diabetic and Pre-diabetic Using Digitalized TCM Diagnostic Tools
The investigators aim to objectively identify the Traditional Chinese Medicine (TCM) syndrome differentiation of type II diabetic and prediabetic patients in Singapore through modern technologies thereby potentially increasing…
- Conditions
- Diabete Mellitus, Pre-diabetes, Healthy, Hypertension
- Trial name
- NCT05563090
- Testing
- Questionnaires+Tongue diagnosis+Pulse diagnosis
- Where
- Singapore
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Singapore Chung Hwa Medical Institution
Dyslipidemia Associated With Type II Diabetes Mellitus
Type 2 Diabetic Patients Maintained on Statin Therapy
Patients with diabetes mellitus (DM) are at increased risk of atherosclerotic cardiovascular disease (ACVD). The achievement of the LDL-C target with statins for the reduction of ACVD risk is recommended.
- Trial name
- NCT03784703
- Testing
- Atorvastatin 40 Mg Oral Tablet, Rosuvastatin 10 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Damanhour University
Diabetes Mellitus, Type 2, Dyslipidemia Associated With Type II Diabetes Mellitus
Effects of Evolocumab on Platelet Reactivity in Patients With Diabetes Mellitus
Prospective, single center, double-blind, randomized pharmacodynamic experimental study. The study will enroll 150 subjects with ASCVD on optimal statin therapy as per physician and Diabetes Mellitus (DM) undergoing elective…
- Conditions
- Diabetes Mellitus, Type 2, Dyslipidemia Associated With Type II Diabetes Mellitus, Percutaneous Coronary Intervention
- Trial name
- ISS-DMII (NCT03258281)
- Testing
- Evolocumab
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Inova Health Care Services
Prediabetes, Type 2 Diabetes
Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes
Given the data on the active ingredients of Totum-63, this research aims to evaluate the effect of its chronic consumption (24 weeks) on glucose and lipid homeostasis and especially on fasting plasma glucose in volunteers with…
- Conditions
- Prediabetes, Type 2 Diabetes, Hypertriglyceridemia, Obesity
- Trial name
- TOTUM-63 TWO (NCT02868177)
- Testing
- Totum-63
- Where
- 6 sites in France, Ireland and 2 more
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Diabetes Mellitus, Type 2, Dyslipidemia Associated With Type II Diabetes Mellitus
Effects of High Intensity Statin Therapy on Steroid Hormones and Vitamin D in Type 2 Diabetic Men
The aim of the study was to assess the effect of high intensity statin therapy on testicular and adrenal steroids and vitamin D levels in type 2 diabetes males.It is a prospective study, conducted between march 2021 and July…
- Conditions
- Diabetes Mellitus, Type 2, Dyslipidemia Associated With Type II Diabetes Mellitus, Statin Adverse Reaction, Hypogonadism, Male
- Trial name
- NCT05806723
- Testing
- Atorvastatin 40 Mg Oral Tablet
- Where
- Tunisia
- Volunteers
- 104 people
- Sponsor
- Hopital La Rabta
Dyslipidemia Associated With Type II Diabetes Mellitus
Paraclinical Cardiometabolic Risk Assessment in Type 2 Diabetes
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by impaired insulin action and increased cardiometabolic risk.
- Trial name
- NCT07362953
- Where
- Turkey (Türkiye)
- Volunteers
- 2,188 people
- Sponsor
- Tokat Gaziosmanpasa University
Dyslipidemia Associated With Type II Diabetes Mellitus
Efficacy and Safety of the Fixed-dose Combination Atorvastatin/Fenofibrate vs Atorvastatin in Patients With T2D and DLP.
Phase IIIb, randomized, longitudinal, prospective, multicenter study to evaluate the efficacy and safety of the fixed-dose combination atorvastatin / fenofibrate versus atorvastatin on the lipid profile of patients with type 2…
- Trial name
- NCT04882293
- Testing
- Atorvastatin 20 mg / Fenofibrate 160 mg in fixed dose, Atorvastatin (Lipitor ®)
- Where
- Mexico
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.