Clinical trials: Dyspareunia
Dyspareunia, Perineal Tear
Rapidly Absorbing Polyglactin 910 Versus Poliglecaprone 25 for Laceration Repair
To evaluate the rates of dyspareunia with rapidly absorbing polyglactin 910 compared to poliglecaprone 25 using a validated sexual function questionnaire.
- Conditions
- Dyspareunia, Perineal Tear, Sutured Laceration
- Trial name
- NCT03184077
- Testing
- Laceration Repair with Polyglactin 910, Laceration Repair with poliglecaprone 25
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Dyspareunia, Menopause
Genital Laser Treatment in Postmenopausal Patients
Regulation of sexual functions without hormonal support in order to correct the sexual dysfunctions in women with the estrogen hormone lost in the menopausal process.
- Conditions
- Dyspareunia, Menopause, Sexual Activity, Atrophy Vulva
- Trial name
- NCT05631665
- Testing
- Survey results before and after laser treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Female Dyspareunia
A Study of Participants Ages 21-65 Diagnosed With Dyspareunia and the Effects of Low Intensity Shockwave Treatment
Dyspareunia is defined as a complaint of persistent or recurring pain or discomfort associated with attempted or complete vaginal penetration e purpose of this study is to determine the effectiveness of low intensity shockwave…
- Trial name
- NCT05806203
- Testing
- Low intensity shockwave treatment to pelvic floor region plus typical physical therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SoftWave Tissue Regeneration Technologies
Vaginal Discharge, Dyspareunia
Evaluation of a Novel Female Hygiene Device for Postcoital Discomfort
Previous research has shown that semen deposition in the vagina after intercourse leads to dripping, discomfort, and vaginal odor.
- Conditions
- Vaginal Discharge, Dyspareunia, Female Sexual Dysfunction, Vaginitis
- Trial name
- NCT04885556
- Testing
- Tampon-like device for absorption of sexual fluids
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Dyspareunia
Treating Postmenopausal Dyspareunia Where it Hurts
The purpose of this study is to compare the effectiveness of two low doses of estrogen cream applied to a new location for the treatment of moderate or severe pain during sexual intercourse in postmenopausal women.
- Trial name
- NCT03240081
- Testing
- 50mcg estradiol cream, 100mcg estradiol cream
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Post-menopause, Pre-menopause
VEDA Study (DHEA vs Estradiol)
This study is being done to compare two vaginal treatments, vaginal estrogen and vaginal DHEA, that are used to treat vaginal and urinary symptoms related to menopause.
- Conditions
- Post-menopause, Pre-menopause, Sexual Function, Menopause
- Trial name
- NCT07574216
- Testing
- DHEA ovals, Estradiol 0.01% Vag Cream
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Dyspareunia
What is the Nature of Pelvic Floor Muscle Involvement in Dyspareunia?
Dyspareunia, or pain experienced by women during penetrative sexual activities, affects the psychological and sexual health of more than one in five Canadian women [1], yet its pathophysiology is poorly understood [2-4] and…
- Trial name
- NCT04234555
- Testing
- Corticomotor excitability to the pelvic floor muscles, Pelvic floor muscle response to pressure applied at the vulvar vestibule, Pressure pain threshold (PPS)
- Where
- Canada
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Pelvic Organ Prolapse
Effects of Pelvic Floor Muscle Training With & Without Hypopressive Exercises
Pelvic Organ Prolapse (POP) is a prevalent condition affecting women's quality of life due to the descent of pelvic organs caused by weak pelvic floor muscles (PFMs).
- Trial name
- NCT07440875
- Testing
- hypopressive excercises, pelvic training excercises
- Where
- Pakistan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Vulvovaginal Atrophy
Evaluation of the Acceptability and Efficacy of 10 Micrograms of Estradiol Vaginal Tablets vs Promestriene Vaginal Cream
Evaluation of the Acceptability and Efficacy of 10 Micrograms of Estradiol Vaginal Tablets vs Promestriene Vaginal Cream in postmenopausal women aged 45 years or older, with one or more moderate to severe symptoms of vulvovaginal…
- Trial name
- NCT04232813
- Testing
- Estradiol 10 MCG Vaginal Tablet [VAGIFEM], Promestriene Vaginal
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Palacios
Dyspareunia, Endometriosis
Dyspareunia in Women With Endometriosis: Impact of Surgery on Sexual Health
Endometriosis is a disease that affects different areas of individual functioning, including the area of sexual life. Women with endometriosis have an impairment of desire and sexual arousal, orgasmic capacity reducted because of…
- Trial name
- NCT02484196
- Testing
- Questionnaires
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Adenomyosis of Uterus
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms
The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis…
- Trial name
- MUSA3 (NCT07397715)
- Where
- 5 sites in Belgium, Poland and 2 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss GO Trial Group
Vulvovaginal Atrophy
Clinical Study to Evaluate the Efficacy of Prasterone Treatment for Atrophy Vulvovaginal in Postmenopausal Women With Vulvar / Vestibular Pain
A prospective, open, randomized and controlled clinical intervention study in women over 45 years of age with a diagnosis of vulvovaginal atrophy (dryness and / or dyspareunia, etc.) and vulvar and / or vestibular pain.
- Trial name
- ROSA (NCT04898556)
- Testing
- Prasterone 6.5 MG
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dr. Santiago Palacios
Vaginismus
Botulinum Toxin Injection for Treatment of Vaginismus
According to high rate of vaginismus (about 10 percent) which leads to unconsummated marriage (about 1 percent) and low efficacy for conventional treatments such as biofeedback therapy, analgesic drugs and pain killers and…
- Trial name
- NCT00638066
- Testing
- botulinum toxin, botulinum toxin A
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness
To Assess Signs and Symptoms in Women Affected by GSM After One Cycle of Pixel CO2-Alma Fractionated Laser
Genitourinary syndrome of menopause (GSM) occurs in approximately 50% of menopausal women but is both underrecognized and undertreated despite numerous treatment options.
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness, Burning, Pain
- Trial name
- NCT05156502
- Testing
- Fractionated Laser (Pixel CO2-Alma), Fractionated Laser (Pixel CO.2-Alma)
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr. Filippo Murina
COVID-19, Dyspareunia
Postpartum Sexual Function in Pregnant Women With COVID-19
The aim of this study is to identify women with postpartum sexual dysfunction and dyspareunia risk in the early period and to use the treatment and care services they need effectively.
- Conditions
- COVID-19, Dyspareunia, Postpartum Period
- Trial name
- NCT04389489
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pain, Postoperative, Neural Therapy of Huneke
Evaluation of the Neural Therapy Effect on Long Term Postoperative Discomforts in Patients Who Undergo Bilateral Tubal Ligation
The aim of this study was to explore the effect of neural therapy on postoperative pain and discomfort such as abdominal swelling; and gynecologic symptoms such as dysmenorrhea, dyspareunia, amount of menstrual bleeding and…
- Conditions
- Pain, Postoperative, Neural Therapy of Huneke, Dysmenorrhea, Dyspareunia
- Trial name
- NCT03761862
- Testing
- Neural Therapy
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pelvic Radiotherapy, Gynecological Cancer
Laser Therapy Following Radiotherapy for Gynecological Cancer
Women with a history of pelvic radiotherapy due to gynecological cancer, will receive laser therapy for the management of genitourinary syndrome of menopause.
- Conditions
- Pelvic Radiotherapy, Gynecological Cancer, Dyspareunia, Vaginal Dryness
- Trial name
- NCT03714581
- Testing
- Microablative Fractional CO2 Laser Therapy
- Where
- Greece
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Ehlers-Danlos Syndrome (EDS)
Impact of Ehlers-Danlos Syndrome on Gynaecological Health
Dysmenorrhea is a common problem in gynaecology, significantly impacting patients' quality of life. Ehlers-Danlos syndrome (EDS) is associated with joint hypermobility, tissue fragility and chronic pain.
- Trial name
- GYNESED (NCT07151274)
- Where
- France
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Episiotomy Wound
Comparison Between Lidocaine Prilocaine Cream and Lidocaine Injection on Pain Control During Episiotomy.
The present study aims to compare the effects of lidocaine-prilocaine cream and lidocaine injection on the reduction of pain while doing and repairing episiotomy, controlling the pain in the post-partum period, and reduction the…
- Trial name
- NCT05891132
- Testing
- 10 ml of lidocaine 2%, lidocaine prilocaine cream 15gm
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Superficial Dyspareunia
Management of Women With Superficial Dyspareunia
Superficial dyspareunia are persistent or recurrent pains during an attempt at sexual intercourse or during effective penetration. They affect between 3 to 18% of women and are a source of physical and psychological suffering.
- Trial name
- dyspareunie (NCT06142851)
- Testing
- Data collection
- Where
- 2 sites in France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne