Clinical trials: Dysphagia
COVID-19, Dysphagia
The Correlation Between COVID-19 and Dysphagia in Adults With Swallowing Disorders
This study aims to investigate the correlation between COVID-19 and dysphagia in adults. The population of the study consisted of those who applied to Bezmialem University, Department of Otorhinolaryngology, Dysphagia Outpatient…
- Trial name
- NCT06135207
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Bezmialem Vakif University
Gastroesophageal Reflux Disease
Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease
The aim of this study was to evaluate the effect of 14 days treatment with Pantoprazole 40 mg and 20 mg on gastroesophageal reflux disease (GERD) related symptoms in a large patient population.
- Trial name
- PARADE (NCT00829738)
- Testing
- Pantoprazole
- Where
- 717 sites in Germany
- Volunteers
- 4,188 people
- Sponsor
- Nycomed
Deglutition Disorder, Dysphagia
The Turkish Feeding/Swallowing Impact Survey
The purpose of this study is to test the reliability and validity of the Turkish Feeding/Swallowing Impact Survey among caregivers of pediatric patients with swallowing disorders.
- Conditions
- Deglutition Disorder, Dysphagia, Outcome Assessment, Quality of Life
- Trial name
- NCT03005093
- Testing
- CAREGIVERS, CHILDREN OF CAREGIVERS
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Gastroesophageal Reflux
Physiological Predictors of Clinical Outcomes After Anti-reflux Surgery
Gastro-oesophageal reflux disease (GORD) is a common condition, where acid from the stomach leaks up into the oesophagus (gullet) and causes symptoms such as heartburn and an unpleasant taste in the back of the mouth.
- Trial name
- NCT03390634
- Testing
- Gastroesophageal reflux symptoms questionnaires
- Where
- United Kingdom
- Volunteers
- 343 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Stroke, Acute Stroke
Effectiveness of Best Care Practices in Acute Stroke in Conventional Hospitalization (BEST CARE ICTUS_HC)
The goal of this clinical trial is to evaluate whether a multicomponent nurse-led intervention (BEST CARE ICTUS_HC) can reduce stroke-related complications and improve recovery in adults (18 years and older) hospitalized with an…
- Conditions
- Stroke, Acute Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- BESTCAREICTUS (NCT07627399)
- Testing
- BEST CARE ICTUS_HC BUNDLE
- Where
- 4 sites in Spain
- Volunteers
- 700 people
- Sponsor
- University of Malaga
Gastroesophageal Reflux Disease
The Clinical Significance of Minimal Change in Reflux Esophagitis Based on the Gastroesophageal Reflux Disease Questionnaire
The purpose of this study is to define the endoscopic findings of minimal change that is significant to clinical significant reflux esophagitis.
- Trial name
- MIGHT (NCT00901004)
- Where
- 7 sites in South Korea
- Volunteers
- 1,550 people
- Sponsor
- AstraZeneca
Laryngopharyngeal Reflux Symptoms, Laryngopharyngitis Chronic
Kazakh Version of Reflux Symptom Index
Reflux symptoms index (RSI) were developed to identify a clinical index of suspicion for laryngopharyngeal reflux (LPR) in patients with ear, nose, and throat symptoms.
- Conditions
- Laryngopharyngeal Reflux Symptoms, Laryngopharyngitis Chronic, Gastro Esophageal Reflux Disease
- Trial name
- NCT05296655
- Testing
- Reflux Symptom Index Inventory (diagnostic survey), Reflux finding score
- Where
- 2 sites in Kazakhstan
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Kazakh Medical University of Continuing Education
Stroke, Dysphagia
The Relative Effectiveness of BOLUS Versus Continuous Nasogastric Feeding After Stroke: a Proof of Principal Study
Patients with severe strokes are often unable to be take oral diet food and fluids safely because they cannot swallow effectively.
- Trial name
- BOLUS (NCT04011787)
- Testing
- bolus NGT feeding, Continuous NGT feeding, Continuous Glucose Monitoring
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals of North Midlands NHS Trust
Gastroesophageal Reflux
German PMS Trial (AWB) to Evaluate Therapy in Reflux Disease and NSAR-Symptoms
This PMS study had the objective to evaluate under ordinary medical care conditions the efficacy and tolerability of esomeprazole in patients who where treated by general practitioners and internists.
- Trial name
- NCT00567021
- Volunteers
- 67,130 people
- Sponsor
- AstraZeneca
Gastroesophageal Reflux Disease, Heartburn
Do Acid Sensing Ion Channels Contribute to Heartburn?
The purpose of this research study is to learn about whether treating the esophagus with amiloride reduces either the frequency or the time to onset of acid-induced heartburn in patients with nonerosive reflux disease.
- Trial name
- NCT01095133
- Testing
- Amiloride
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of North Carolina, Chapel Hill
Eosinophilic Esophagitis (EoE)
Natural History of Eosinophilic Esophagitis in Adult and Pediatric Population
Eosinophilic esophagitis (EoE) is a Th2-mediated disease induced by ingestion of ambiental and alimentary allergens. Incidence of EoE is increasing in recent years. Young male subjects are more often affected by EoE.
- Trial name
- NCT07614633
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Disorders of Gut-brain Interaction, Lifestyle and Dietary Interventions
Comprehensive Management Strategies for Gastroesophageal Reflux Disease: A Study of Multidimensional Interventions and Health Impacts
Gastroesophageal reflux disease (GERD) is a common gastrointestinal disorder, with around 80% of patients experiencing nighttime symptoms.
- Conditions
- Disorders of Gut-brain Interaction, Lifestyle and Dietary Interventions, Gastroesophageal Reflux Disease
- Trial name
- NCT07754721
- Testing
- Dietary intervention guided by a nutritionist, Written dietary education intervention
- Where
- Taiwan
- Volunteers
- 220 people
- Sponsor
- Hualien Tzu Chi General Hospital
Obesity, Obesity, Morbid
Biological Sample Repository for Gastrointestinal Disorders
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients…
- Conditions
- Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder
- Trial name
- NCT05874726
- Testing
- Blood Collection, Urine Collection, Tissue Sample Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
Cerebrovascular Accident, Healthy Adults
The Performances and Differences in Tongue Function Between Healthy Adults and Dysphagia in Patients With Stroke in Taiwan
Cerebrovascular accident makes adults lose the ability to be independent in daily life, and a higher proportion of them will suffer from dysphagia.
- Trial name
- NCT05920993
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
GERD
Study of a Dietary Supplement for Reflux During Sleep
This research study is a randomized, controlled study developed to test how well a dry mouth product that contains xylitol affects some of the symptoms of gastroesophageal reflux disease (GERD.
- Trial name
- SXDSFRS (NCT02274636)
- Testing
- Xylitol
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oral Care Research Associates, Seattle
Hepatitis C, Deglutition Disorders
Bioequivalence Study of Crushed Elbasvir/Grazoprevir Compared to the Whole Tablet
Elbasvir/grazoprevir (Zepatier®) is a once-daily tablet for the treatment of chronic hepatitis C virus (HCV) GT1a, 1b or 4 infection containing the NS5A inhibitor elbasvir (ELB) 50 mg and the NS3/4A protease inhibitor grazoprevir…
- Trial name
- CRUSADE-2 (NCT03817619)
- Testing
- Zepatier whole tablet, Zepatier crushed tablet
- Where
- Netherlands
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Pulmonary Aspiration of Gastric Contents
Videolaryngoscopy Compared to Direct Laryngoscopy
Videolaryngoscope (Macintosh-type blade) compared with direct laryngoscopy for rapid sequence intubation in the operating room
- Trial name
- LARA (NCT04794764)
- Testing
- McGrath Mac, Macintosh Laryngoscope
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Johannes Gutenberg University Mainz
Dysphagia
The Impact of Practicing Active Breathing Exercises on Elderly Individuals Living in the Community
The goal of this clinical trial is to explore the impact of Active Breathing Exercises on swallowing function and quality of life in community-dwelling elderly individuals (≥60 year old) with swallowing disorders.
- Trial name
- NCT06328192
- Testing
- Active Breathing Exercises
- Volunteers
- 300 people
- Sponsor
- Copka Sonpashan
Rhinitis, Nasal Obstruction
The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate
Gastroesophageal(GERD) reflux disease is a very common problem among pediatric population and has be proved to contribute in numerous otolaryngological manifestations.
- Conditions
- Rhinitis, Nasal Obstruction, GERD
- Trial name
- Pale Turbinate (NCT02278081)
- Testing
- lansoprazole
- Volunteers
- 98 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pharyngeal Dysfunction, Pharyngeal Swallowing
Opioid Effects on Swallowing Comparing Younger and Elderly Volunteers
The purpose of the study is to determine whether remifentanil influence the pharyngeal phase of swallowing using using pressure and impedance recordings.
- Trial name
- NCT01924234
- Testing
- Morphine, Remifentanil
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Region Örebro County