Clinical trials: Dysphagia, completed
Gastroesophageal Reflux
A Study of Dexlansoprazole Modified Release Formulation to Treat Night Heartburn
The purpose of this study is to determine whether Dexlansoprazole once daily (QD) is effective in treating patients with night heartburn.
- Trial name
- NCT00627016
- Testing
- Dexlansoprazole
- Where
- 43 sites in United States
- Volunteers
- 305 people
- Sponsor
- Takeda
Cough, Cough Variant Asthma
MCT and Capsaicin Provocation Challenge in Diagnosis of Chronic Cough
The aim of the study is to assess the prevalence of bronchial hyperresponsiveness (BHR) in non-smoking adults with chronic cough and the prevalence of BHR in patients with upper airway cough syndrome (UACS) and gastroesophageal…
- Conditions
- Cough, Cough Variant Asthma, Upper-Airway Cough Syndrome, GERD
- Trial name
- NCT03363698
- Testing
- Cough variant asthma treatment
- Where
- Poland
- Volunteers
- 55 people
- Sponsor
- Medical University of Warsaw
Cognitive Impairment, Voice Disorders
Correlation Between Montreal Cognitive Assessment and Voice Therapy Outcomes in the Aging Treatment- Seeking Population
This study will investigate if the performance on the Montreal Cognitive Assessment (MoCA) is associated or predictive of the outcomes in voice, swallowing or upper airway therapy in the older laryngology treatment seeking…
- Conditions
- Cognitive Impairment, Voice Disorders, Voicebox Disorders, Cognitive Decline
- Trial name
- MoCA (NCT05187910)
- Testing
- Speech Therapy, Swallowing Therapy, Upper Airway Therapy
- Where
- 4 sites in United States
- Volunteers
- 57 people
- Sponsor
- University of California, San Francisco
Gastroesophageal Reflux Disease, Hiatal Hernia
Transoral Incisionless Fundoplication (TIF) Registry Study for Treatment of Gastroesophageal Reflux Disease (GERD)
The study objective is to evaluate the safety and efficacy of TIF among a broad range of GERD patients treated in routine clinical practice at multiple centers across the United States.
- Trial name
- NCT01118585
- Testing
- TIF Procedure
- Where
- 14 sites in United States
- Volunteers
- 278 people
- Sponsor
- EndoGastric Solutions
Gastro Esophageal Reflux, Dental Erosion
Domiciliary Management of Dental Erosion in Patients With GERD With Biomimetic Hydroxyapatite
The aim of the present study is to evaluate dental erosion in patients with gastroesophageal reflux disease (GERD). Patients consenting to participate to the study will undergo periodontal evaluation at the baseline.
- Trial name
- NCT05371717
- Testing
- Domiciliary use of Biorepair Total Protection + Biorepair Shock Treatment, Biorepair Total Protection
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pavia
Head and Neck Cancer
Pre-habilitation of Patients With Head and Neck Cancer
The purpose of this study is to explore whether early initiated physical exercise concurrent with a swallowing and mouth opening exercise program will have a positive effect on swallowing function and other quality of life…
- Trial name
- SYNK (NCT02385929)
- Testing
- Swallowing therapy & resistance training
- Where
- 2 sites in Denmark
- Volunteers
- 240 people
- Sponsor
- Irene Wessel
Cerebral Palsy
Oral Enteral Nutrition in Infants With Cerebral Palsy and Dysphagia
This was a randomized controlled study including 80 infants with cerebral palsy and dysphagia. The Participants were evenly divided into the observation group (with intermittent oro-esophageal tube feeding, n=40) and the control…
- Trial name
- NCT06303934
- Testing
- systemic therapy, Intermittent Oro-Esophageal Tube Feeding, Persistent Nasogastric Tube Feeding
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Muhammad
Lung Transplant, Dysphagia
TEE and Dysphagia in Lung Transplantation
The primary outcome of this study is dysphagia (difficulty swallowing) on postoperative speech and swallow evaluation following lung transplantation.
- Trial name
- NCT06089434
- Testing
- Transesophageal Echocardiography (TEE) with limited number of TEE clips, Transesophageal Echocardiography (TEE) with number of TEE clips per attending anesthesiologist
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of California, Los Angeles
Gastroesophageal Reflux Disease, Erosive Esophagitis
Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in Adolescents
The purpose of this study is to assess the safety and effectiveness of treatment with once daily oral administration of dexlansoprazole delayed-release capsules in adolescents with erosive esophagitis (EE) and for maintenance of…
- Trial name
- NCT01642615
- Testing
- Dexlansoprazole
- Where
- 60 sites in United States, Belgium and 6 more
- Volunteers
- 63 people
- Sponsor
- Takeda
Deglutition Disorders, Nutritional Deficiency
Coverage of Requirements After Consumption of a Nutritional Formula in Patients With Chewing/Swallowing Problems.
Effect of a nutritional formula on the nutritional requirements in patients with chewing/swallowing problems during one month
- Conditions
- Deglutition Disorders, Nutritional Deficiency, Chew Problems, Swallowing Disorder
- Trial name
- VEGENAT MED (NCT03727191)
- Testing
- Control Group (education, guidelines, recommendations), Experimental Group (education, guidelines, 2 pckts diet, recommendations)
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Dysphagia, Stroke
NMES Plus Conventional Therapy for Stroke Dysphagia
Aim: The aim of this study is to investigate the effect of neuromuscular electrical stimulation (NMES) combined with traditional dysphagia therapy (TDT) in acute/subacute stroke patients with dysphagia.
- Trial name
- NCT07415785
- Testing
- neuromuscular electrical stimulation, traditional dysphagia therapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chiayi Christian Hospital
Dysphagia After Stroke, Aspiration Pneumonias
Tongue Brush (Orabrush) for Reducing Aspiration Pneumonia in Stroke Patients
The investigators conduct a controlled prospective experimental intervention study to examine whether the use of a tongue brush (Orabrush) can improve the rate of aspiration pneumonia and dysphagia in patients with ischemic…
- Conditions
- Dysphagia After Stroke, Aspiration Pneumonias, Ischemic Stroke
- Trial name
- StrOra (NCT06765018)
- Testing
- Tongue Brush (Orabrush)
- Where
- Germany
- Volunteers
- 252 people
- Sponsor
- University Hospital Marburg
Stroke, Dysphagia
Pilot Study of Efficacy of Mechanical Insufflation Exsufflation in Stroke
Stroke patients with dysphagia have restrictive lung dysfunction and impaired cough response. This pilot study was performed to determine if Mechanical Insufflation Exsufflation (MIE) therapy can help recover impaired cough…
- Trial name
- NCT02080806
- Testing
- Mechanical Insufflation Exsufflation
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- The Catholic University of Korea
Sarcopenia, Dysphagia
Feasibility and Impact of Resistance Training for Sarcopenic Dysphagia
The purpose of the study is to test and optimize the feasibility of an activity-based resistance training program for patients with sarcopenic dysphagia.
- Trial name
- NCT05269758
- Testing
- activity-based resistance training of ingestive skills (ACT-ING-program)
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- Hvidovre University Hospital
Dysphagia, Dysphonia
Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection (DYADS Study)
This study examines the presence, severity and natural history of dysphagia and dysphonia in the post-extubation and severely unwell COVID-19 patient.
- Conditions
- Dysphagia, Dysphonia, Subglottic Stenosis, Voice Disorders
- Trial name
- DYADS (NCT04584658)
- Testing
- Fibreoptic Endoscopic Evaluation of Swallowing (FEES), Videofluoroscopy, Dysphagia Handicap Index (DHI)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Gastro Esophageal Reflux
Effect of Right Lateral Position on Ventilated Preterm Neonates
Objective: to evaluate the effect of right lateral positioning in comparison with supine positioning on tracheal aspirate pepsin levels as a marker of aspiration of gastric contents in ventilated preterm neonates.
- Trial name
- NCT03258528
- Testing
- positioning
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Stroke
Neuromuscular Electrical Stimulation Versus Electromyographic Biofeedback on Oropharyngeal Dysphagia in Patients With Stroke
This study aims to investigate the effect of neuromuscular electrical stimulation versus electromyographic biofeedback on swallowing function and dysphagia severity in patients with stroke.
- Trial name
- NCT07367490
- Testing
- Neuromuscular electrical stimulation, Electromyographic Biofeedback, Selected physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Air Insufflation, Regurgitation
Risk of Gastric Insufflation Related to Facemask Ventilation Technique During Anaesthetic Induction, With or Without PEEP
Continuous positive pressure during anesthetic induction is today not routinely used partly a to the risk of gastric insufflation because of higher ventilatory pressures.
- Trial name
- NCT02238691
- Testing
- Mask ventilation with PEEP via a face mask device
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Cholecystolithiasis, Cholecystectomy
Does Cholecystectomy Increase the Esophageal Alkaline Reflux? Evaluation by Impedance-pH Technique
Publications with different conclusions are available with regard to the correlations between the cholecystolithiasis, cholecystectomy and gastroesophageal reflux disease (GERD).
- Conditions
- Cholecystolithiasis, Cholecystectomy, Gastroesophageal Reflux
- Trial name
- NCT01047085
- Testing
- impedance pH measurement
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Nutrition Disorders, Gastrointestinal Disease
Review of Infant Oral Feeding and Skills
This study evaluates the infant's feeding skill level at discharge from the neonatal intensive care unit. The goal is to determine whether the ability to "full feed by volume" implies "full skill development" for infant oral…
- Conditions
- Nutrition Disorders, Gastrointestinal Disease, Deglutition Disorder, Feeding Difficulties
- Trial name
- RIOS (NCT06736743)
- Testing
- SMART Tool for Feeding Skill Assessment
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Wake Forest University Health Sciences
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